Purpose: The purposes of this study were to identify factors influencing on attitudes towards people with disabilities in college students. Methods:　The study targets were college students who were studying at 3 colleges in G city and the date were collected using a structured questionnaire. Data were collected from October to November of 2016 through a self-report structured questionnaire. Data were analyzed by descriptive statistics, t-test, ANOVA, Scheffe test, Person s correlation coefficients, and Hierarchical multiple regression analysis using SPSS 23.0 program. Results:　The awareness of people with disabilities(β=.32, p<.001) gives an impact on the works of college students’ attitude of people with disabilities, and its power of explanation reveals as 41.6%. Based on this study. Conclusions: I would like to suggest to develop various programs that focused on improving the positive awareness of the disabled to have a positive attitude toward college students.