This study aimed to investigate the effectiveness of a depression management program based on cognitive behavioral therapy, focusing on Socially Prescribed Perfectionism, Intolerance of Uncertainty, Rumination. According to the criteria over CES-D score 16 or more, the treatment group (n=12) and the waiting-control group (n=12) were selected. The depression management program based on CBT consisting of 8 sessions was conducted for the treatment group. To test the effectiveness of the program, Socially Prescribed Perfectionism (HMPS), Depression (CES-D), Intolerance of Uncertainty(IUS), Rumination(RDQ) were measured at pre, post, and follow-up (6 months) tests. As a result of the study, in the treatment group, the dependent variables measured post and follow-up treatments were significantly decreased compared to pre-test, but there was no significant change in the waiting-control group. It means that the program is effective in reducing the levels of Socially Prescribed Perfectionism, Depression, Intolerance of Uncertainty, and rumination in the treatment group and maintaining the effect for 6 months. It suggests that the intervention for the Socially Prescribed Perfectionism, Intolerance of Uncertainty and rumination is useful for managing Depression in college students. Based on the research results, the limitations, suggestions, and significance of this study were discussed.