This study aimed to obtain implications on childrearing and childcare practices for achieving children's well-being through analyzing factors predicting children's well-being during the COVID-19 pandemic in eight Asian countries. We primarily focused on “resilience,” the ability to cope with and recover from difficult situations, which had been confirmed from previous studies as a positive factor towards children’s development in the context of hardships. We also chose other potential predictors referring to Bronfenbrenner’s ecological systems theory, including mothers’ concerns about COVID-19, household income, number of playmates, support from childcare facilities/schools, family environments, and children’s lifestyles, and examined how these predictor variables predict children’s well-being. We found that children’s resilience strongly predicted their well-being, which was common in all eight countries. Family factors and children's daily life factors were also associated with children's well-being. The country-specific analysis also indicated the importance of support from childcare facilities/schools on well-being. Well-being and resilience are both psychological constructs and often studied as important indicators of child health. Resilience has been spot-lighted as an effective protective factor for children experiencing adversities such as the COVID-19 pandemic. We have found that resilience was the strongest predictor of well-being among other factors even during the COVID-19 pandemic.