Purpose: This study was done to investigate worker's performance of infection control measures in nursing homes for elderly people. Methods: Between October 2009 to April 2010, data were collected using self-report questionnaires. Study participants were 203 workers in these nursing homes and 71.4% were direct caregivers. Data were analyzed using t-test, ANOVA, Duncan test with SPSS/WIN 12.0. Results: The overall mean for performance score for infection control was 3.65 (range 1~4) and the score for environmental management was 3.75, for urinary infection control, 3.70, for personal hygiene, 3.66, for respiratory infection control, 3.64, for drug and injection management, 3.63, for hand washing, 3.59, and for disinfection and supply management, 3.57. Gender, age, education level, occupation, need for infection control in the facility and education about infection control, and probability of being an infection carrier were significantly related to performance level. A high number (69%) of workers answered "not in the habit" as a reason for non-performance of hand washing. Conclusion: These results indicate a need to develop standard infection control guidelines and education programs for workers in nursing homes for elders. These guideline and program should lead to improvements in infection control activities of these workers.