This study aims to examine whether a structural relationship exists among disability identity, social support, career barriers, and career decision making of young adults with disabilities and to propose a career decision making model by identifying a mediating effect of self-efficacy on career decision-making. Participants in this study were 601 people who have graduated from or are attending at four-year universities across the nation. An effect of mediating variable through Path analysis by applying structural equation model was also conducted. Results of structural equation model indicated that disability identity, social support, career barriers, career decision-making self-efficacy had a significant impact on participants' career decision making. Namely, higher degree of disability identity, stronger social support, higher level of self-efficacy, and decrease in career barriers positively influenced participants' career decision making. Findings also suggested that career decision-making self-efficacy partially played a mediating role between career decision making and career barriers, social support, and disability identity among participants. Based on the findings, it can be inferred that more effort to develop feasible and practical policies to facilitate employment and social integration for young adults with disabilities. Further, disability resources centers at higher educational institutions should create and implement a service delivery program to improve disability identity, strengthen social support, lower the career barriers, and enhance self-efficacy for college attending student with disabilities. Finally, rehabilitation professionals must pay a great deal of attention in order to help young adults with disabilities who are attending at or have graduated from colleges to choose and realize his or her desired career goals.