The purpose of this study was to investigate the effect of exercise training on work capacity, psychologic functions and quality. of life in hemodialysis patients. Forteen hemodialysis patients, 3 males, 11 females, age ranged from 23~58 years(42.3±0.4) were selected and assessed using a modified Bruce protocol on a treadmill. The 3 months supervised exercise training consisted of 60 minites session thrice weekly on the treadmill, bicycle and arm ergometer at 40~60% of maximum O₂ consumption. The changes of maximum O₂ consumption, psychologic test and quality of life questionnaire in 14 patients before and after 3 months exercise training have been measured. The mean maximum O₂ consumption(VO₂ max) of exercisers increased by 23% after training(pre-and postexercise 26.3±4.6ml/kg/min vs 29.8±4.9ml/kg/min, p=0.013). There was significant reduction in anxiety score(p=0.004) and significant improvement in quality of life score(p=0.031) after training. The result of this study indicated that a structured exercise training for hemodialysis patients provides many benefits. These result suggest the exercise training can improve the work capacity, psychologic functions and quality of life outcomes in hemodialysis patients.