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Calcium Modulates Excitatory Amino Acid (EAA)- and Substance P-induced Rat Dorsal Horn Cell Responses
HongKeeShin, SokHanKang, InDukChung, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 5 35-45 (11 pages)
spinal cord. In this study, we examined how Ca2 modified the responses of dorsal horn neurons to single or combined iontophoretical application of EAA and SP in the rat. All the LT cells tested responded to kainate, whereas about 55% of low threshold (LT) cells responded to iontophoretically applied NMDA. NMDA and kainate excited almost all wide dynamic range (WDR) cells. These NMDA- and kainate-induced WDR cell responses were augmented by iontophoretically applied EGTA, but suppressed by... -
Microinjection of Glutamate into the Amygdala Modulates Nociceptive and Cardiovascular Response in Freely Moving Rats
Dong-KukAhn, Yun-SookKim, Jae-SikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 5 687-693 (7 pages)
This study was performed to examine the mean arterial pressure and nociceptive jaw opening reflex after microinjection of glutamate into the amygdala in freely moving rats, and to investigate the mechanisms of antinociceptive action of amygdala. Animals were anesthetized with pentobarbital sodium (40 mg/kg, ip). A stainless steel guide cannula (26 gauge) was implanted in the amygdala and lateral ventricle. Stimulating and recording electrodes were implanted into each of the incisor pulp and... -
External pH Effects on Delayed Rectifier K+ Currents of Small Dorsal Root Ganglion Neuron of Rat
YoungHoKim, JungHyunHahn, InJaLim, SungkwonChung, HyoWeonBang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 4 165-172 (8 pages)
Under certain pathophysiological conditions, such as inflammation and ischemia, the concentration of H+ ion in the tissue surrounding neurons is changed. Variations in H+ concentration are known to alter the conduction and/of the gating properties of several types of ion channels. Several types of K+ channels are modulated by pH. In this study, the whole cell configuration of the patch clamp technique has been applied to the recording of the responses of change of external pH on the delayed... -
Sensory Inputs to Upper Cervical Spinal Neurons Projecting to Midbrain in Cats
JongHoKim, Han-SeongJeong, Jong-SeongPark, Jong-KeunKim, Sah-HoonPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.1 2 9-19 (11 pages)
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쥐 척수후각세포의 유해자극 반응에 대한 칼슘이온통로 차단제의 억제작용 Calcium Channel Blockers Suppress the Responses of Rat Dorsal Horn Cell to Nociceptive Input
신홍기, 강석한, 김기순, HongKeeShin, SokHanKang, KeeSoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.6 3 625-637 (13 pages)
on the acute and tonic pain behaviors resulting from thermal stimulation, subcutaneous formalin injection and nerve injury. This study was undertaken to investigate the effects of iontophoretically applied Ca and its antagonists on the responses of WDR (wide dynamic range) cells to sensory inputs. The responses of WDR cells to graded electrical stimulation of the afferent nerve and also to thermal stimulation of the receptive field were recorded before and after iontophoretical... -
Study on Ginseng Protopanaxadiol and Protopanaxatriol Saponins- Induced Antinociception
Young-HeeShin, Seok-ChangKim, Ji-WonHan, Dae-HoonKim, Sang-SubHan, Dong-HoShin, Seung-YeolNah 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.2 4 143-149 (7 pages)
mg/kg for PT saponins in second phase of formalin test. For first phase pain inhibition by PD or PT saponins, they were required higher concentrations. However, PD saponins showed weak analgesic effects in tail-flick test with high concentration. In conclusion, we found that both PD and PT saponins have the analgesic effects in writhing test and second phase of pain in formalin test. These results suggest that both PD and PT saponins inhibit neurogenic or tonic pain rather than acute pain. -
Combination of Electroconvulsive Therapy and Clozapine in Treatment-Resistant Schizophrenia
Jung Hyun Kim, Tak Youn, Jun Gwon Choi, Seong Hoon Jeong, Hee Yeon Jung, Yong Sik Kim, In Won Chung 대한신경정신의학회 Psychiatry Investigation 7 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 13 829-835 (7 pages)
Objective_This study aimed to investigate the effectiveness and tolerability of the combination of electroconvulsive therapy (ECT) in patients with clozapine-treated schizophrenia. Methods_Patients with clozapine-treated schizophrenia during five years of pre-determined period were recruited from Electronic Medical Record. Clinical effects of acute ECT on psychotic symptoms were investigated. We also tried to identify predictive variables requiring maintenance treatment of ECT. Results_Fourteen... -
정신분열병 환자의 통증 감지력 둔화와 압통 역치
송지영, 이장호 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 1호 2 14-22 (9 pages)
연구목적: 정신분열병 환자에서 통증자극에 따른 감지력이 저하되어 있는지를 압통역치를 이용하여 알아보고, 만일 통증감지력이 저하되어 있다면 이는 어떠한 정신증상과 관련되는지를 밝혀 보고자 하였다. 방 법: 정신분열병환자 21명(남자 8명, 여자 13명)과 건강대조군 23명(남자 9명, 여자14명)을 대상으로 하여, 환자군에게 양성 및 음성증상을 측정하고, 양군에서 압통측정기를 이용하여 압통역치를 측정하였다. 양군에 서 압통역치의 차이를 분석하고, 증상의 호전도에 따른 압통역치의 변화를 보았다. 결 과:... -
Human Cerebellar Activation during Painful Cold Stimulation:a Functional Magnetic Resonance Imaging Study
Seung-Schik Yoo, Byung Gil Choi, Chang Uk Lee, Bum Soo Kim, , Su Jung Yoon, Soo Jung Lee, Tae Kim, Jung Jin Kim, Chul Lee, In Ho Paik 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 4호 16 727-733 (7 pages)
연구목적: 본 연구에서는 기능적 자기공명영상법(fMRI)을 이용하여 동통 한랭 자극 동안의 소뇌 활동정도를 알아보 았다. 방 법: 6명의 건강한 자원자들을 선발하여 1.5 Tesla MR scanner 안에 누워 있는 동안 그들의 좌측 손에 0~3℃의 얼음주머니를 올려놓아 동통 한랭 자극을 주었다. 자극과 연관된 BOLD(blood oxygenation level dependent) 반응을 평가하기 위해 일련의 susceptibility-weighted MR image를 측정하였고 대뇌활동 영 역을 시각화하고 정량화하는 statistical parametric map을 작성하였다. 결 과: 한랭 자극으로... -
바이오피드백 훈련이 만성 두통 환자의 임상 증상 및 스트레스 반응에 미치는 효과
장명선, 하양숙, 정진상, 유범희 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2004, 제 43권 제 6호 12 697-705 (9 pages)


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