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1101.

흰쥐 말초 혈액 림프구의 분자량 44 kD 단백의 인산화

안영수(Young Soo Ahn), 주일로(I-Lo Jou), 오도연(Do Yeun Oh), 임승욱(Seung Wook Lim), 박경선(Kyung Sun Park) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1991, 제 27권 제 2호 6 135-144 (10 pages)

안영수(Young Soo Ahn), 주일로(I-Lo Jou), 오도연(Do Yeun Oh), 임승욱(Seung Wook Lim), 박경선(Kyung Sun Park) 저
...
- 3,000원
흰쥐 말초혈액에서 얻은 T 림프구를 아드레날린성 β-수용체 효현제 및 concanavalin A(Con-A)로 자극해 다음과 같은 결과를 얻었다. 자극이 없는 상태에서의 주 인산화 단백은 분자량 44kD, 등전점 6.8의 단백이었으며 효현제로 자극시키면 분자량 44kD, 등전점 6.3의 단백이 새로이 인산화되어 나타났다. 이 분자량 44kD, 등전점 6.3의 단백은 forskolin에 의해 역시 인산화되며 A-kinase 억제제인 H-8을 전처치하면 인산화의 억제가 나타났다. 또한 Con-A로 자극시키면 44 kD/pI 6.3 단백의 인산화가 증가되었으며 이 인산화의 증가는...
1102.

흰쥐 적출 부신에서 Metoclopramide의 Catecholamine 분비작용에 관한 연구

임동윤(Dong Yoon Lim), 김규형(Kyu-Hyeong Kim), 최철희(Cheol Hee Choi), 유호진(Ho-Jin Yoo), 최동준(Dong Joon Choi), 이은화(Eun-Hwa Lee) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 1989, 제 25권 제 1호 4 31-42 (12 pages)

임동윤(Dong Yoon Lim), 김규형(Kyu-Hyeong Kim), 최철희(Cheol Hee Choi), 유호진(Ho-Jin Yoo), 최동준(Dong Joon Choi), 이은화(Eun-Hwa Lee) 저
...
- 4,100원
Metoclopramide (MCP)는 역류성식도염, 위하수증, 항암제에 의한 구토 증상을 치료하는데 사용되고 있는 dopamine수용체 차단제로 알려져 있다. 본 연구에서는 흰쥐의 적출 관류부신에서 catecholamine (CA)의 분비작용에 미치는 영향을 검토하여 다음과 같은 결과를 얻었다. MCP는 부신정맥내로 주입하였을때 용량의존적으로 CA 분비작용을 나타냈다. 이러한 MCP의 CA 분비작용은 atropine 전처치로 차단되었으나 chlorisondamine 처치에 의해서는 완전 차단되지 못하였다. MCP 분비작용은 physostigmine, adenosine, ouabain의 전처치로...
1103.

Pyrantel pamoate 및 Oxantel pamoate 합제(合劑)의 장내선충류(腸內線蟲類)에 대(對)한 구충효과(驅蟲效果)

조승열(Seung-Yull Cho) 대한약리학회 대한약리학잡지 5 Pages

대한약리학회 대한약리학잡지 1976, 제 12권 제 1호 8 69-73 (5 pages)

조승열(Seung-Yull Cho) 저
...
- 1,500원
1104.

Enhanced Vasorelaxation Response to Cromakalim in Spontaneously Hypertensive Rats

Kim, Se-Hoon, Oh, Yeong-Seon, Kim, Hoe-Suk, Jeon, Byeong-Hwa, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 2 11-20 (10 pages)

Kim, Se-Hoon, Oh, Yeong-Seon, Kim, Hoe-Suk, Jeon, Byeong-Hwa, Chang, Seok-Jong 저
...
- 3,000원
M norepinephrine (NE) dose-dependently, and this relaxant response to cromakalim was blocked by 10-5 M glybenclamide. 2. Cromakalim also relaxed the contraction induced by high K+-solution or 10 mM tetraethylammonium dose-dependently. However, the relaxant response to cromakalim was decreased by raising the K+ concentration. 3. SHR aorta exhibited myogenic tone in resting state which was inhibited by cromakalim, verapamil or Ca2+-free PSS. Whereas, WKY aorta did not exhibit any myogenic tone in...
1105.

Effects of Adenosine on the Ionic Channel Activated by Metabolic Inhibition in Rabbit Ventricular Myocytes

Han, Jin, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 1 1-10 (10 pages)

Han, Jin, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 저
...
- 3,000원
The objective of the present study was to characterize the role of adenosine in regulation of ATP-sensitive K+ channel (KATP channel) activity in isolated rabbit ventricular myocytes using the patch clamp technique. Internal adenosine had little effects on KaTr channel activity. In an outside-out patch with intrapipette GTP and ATP, external adenosine stimulated KATP channel activity. In an inside-out Patch with intrapipette adenosine, ATP reduced KATP channel activity, and GTP stimulated KATP...
1106.

Effects of Insulin and IGFS on Growth and Functional Differentiation in Primary Cultured Rabbit Kidney Proximal Tubule Cells -Growth and membrane transport-

Han, Ho-Jae, Park, Kwon-Moo, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 1 191-202 (12 pages)

Han, Ho-Jae, Park, Kwon-Moo, 저
...
- 4,100원
The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at 5 X 10-10M. IGF-II(5 X 10 -10 M) did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents...
1107.

Calcium Current in the Unfertilized Egg of the Hamster

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 12 215-224 (10 pages)

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 저
...
- 3,000원
The presence of a calcium current (iCa2+) passed via a specific channel was examined in the unfertilized hamster egg using the whole-cell voltage clamp technique. Pure inward current was isolated using a Ca2+-rich pipette solution containing 10 mM TEA. This current was independent of external Na+ and was highly sensitive to the Ca2+ concentration in the bathing solution, indicating that the inward current is carried by Ca2+. The maximal amplitude was -4.12±0.58nA (n=12) with 10mM Ca2+ at -3OmV...
1108.

Effects of cGMP on the Contractility and Ca Movement in the Aorta of Normotensive Wistar-Kyoto Rats and Spontaneously Hypertensive Rats

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 8 181-190 (10 pages)

Park, Hae-Kun, Jeon, Byeong-Hwa, Kim, Se-Hoon, Kim, Hoe-Suk, Chang, Seok-Jong 저
...
- 3,000원
a dose-dependent manner (10-6 ~ 10-4 M) in the endothelium-rubbed aortic strips of both strains. Also norepinephrine (10-6 M)-induced contractions in normal and Ca-free Tyrode s solution were suppressed by the pretreatment with 8-Br-cGMP (10-4 M) in either strain. However, the amplitudes of suppression induced by 8-Br-cGMP were greater in SHR than that in WKY. Basal 45Ca uptake and 40mM K+-stimulated 45Ca uptake were not suppressed by pretreatment with 8-Br-cGMP (10-4 M) in single aortic smooth...
1109.

The Effects of Bombesin on the Afferent Sensory Transmission in the Spinal Trigeminal Nucleus of Anesthetized Rats

Shin, Hyung-Cheul, Won, Chung-Kil, Kim, Jun, Park, Hyoung-Jin 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 11 105-112 (8 pages)

Shin, Hyung-Cheul, Won, Chung-Kil, Kim, Jun, Park, Hyoung-Jin 저
...
- 3,000원
The present study was carried out to determine the effects of intracisternal administration of three doses of bombesin (0.001, 0.01 and 0.1 μg) on afferent somatosensory transmission in single neurons of the spinal trigeminal nucleus of anesthetized rats. Lower doses (0.001 μg) of bombegin did not change the afferent sensory transmission. Medium doses (0.01 μg) of bombesin significantly (p p<0.01) facilitated afferent sensory transmission in the 6 to 30 min post-drug period, but higher doses...
1110.

Effects of Lemakalim, a Potassium Channel Opener, on the Contractility and Electrical Activity of the Antral Circular Muscle in Guinea-Pig Stomach

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 4 37-50 (14 pages)

Kim, Sung-Joon, Jun, Jae-Yeoul, Choi, Youn-Baik, Kim, Ki-Whan, Kim, Woo-Gyeum 저
...
- 4,300원
on membrane currents and single channel activities were also measured in single smooth muscle cells and excised membrane patches by using the patch clamp method. Lemakalim induced hyperpolarization and inhibited spontaneous contractions in a dose-dependent manner. These effects were blocked by glibenclamide and low concentrations of tetraethyl ammonium (< mM). Glibenclamide blocked the effect of lemakalim on the membrane potential and slow waves. The mechanoinhibitory effect of lemakalim was...

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