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121.

Na+ 및 K+에 의한 심장근 Mitochondria에서의 Ca++ 유리작용

김명석(Myung Suk Kim) 대한약리학회 대한약리학잡지 12 Pages

대한약리학회 대한약리학잡지 제 14권 제 1,2호 1 1-12 (12 pages)

김명석(Myung Suk Kim) 저
...
- 4,100원
보였다. 부전심근 mitochondria에서의 Na+에 의한 Ca++유리는 정상심근 mitochondria에서와 같았으며 이때 digitalis 강심배당체가 직접적으로는 별 영향을 미치지 않았다. 이상에서 심근의 경우 mitochondria는 세포내 Ca++을 조절할 수 있는 기구로서 심근수축의 E-C coupling과정에서 세포막의 전기적 흥분현상과 결부하여 Ca++을 유리할 수 있을 것으로 추정하였으며, 한편 digitalis배당체의 강심작용기전에 있어서는 digitalis 배당체에 의한 세포막의 Na+, K+-ATPase 억제결과 초래될 수 있는 세포내의 Na+ 증가 및(또는) K+감소가...
122.

부자(附子) 부타놀 분획(分劃)이 심근(心筋) 수축단백(收縮蛋白)에 미치는 영향(影響)

양길성(Kil-Sung Yang), 박길수(Kil-Soo Park), 박찬웅(Chan-Woong Park), 임정규(Jung-Kyoo Lim) 대한약리학회 대한약리학잡지 8 Pages

대한약리학회 대한약리학잡지 1976, 제 12권 제 1호 3 23-30 (8 pages)

양길성(Kil-Sung Yang), 박길수(Kil-Soo Park), 박찬웅(Chan-Woong Park), 임정규(Jung-Kyoo Lim) 저
...
- 3,000원
최근(最近) 현저한 심근수축증강작용(心筋收縮增强作用)이 알려져 있는 부자(附子) 「부타놀」 분획의 작용기전(作用機轉)을 구명(究明)코저 하는 시도(試圖)의 일환으로 심근수축단백(心筋收縮蛋白)에 대한 직접적인 영향을 관찰하였다. 부자「부타놀」 분획은 actomyosin ATPase 활성(活性)에 대하며 별(別) 영향을 미치지 않았으며 actin-myosin 상호결합(相互結合)에서 Ca++과 유사한 역활을 나타내지도 못했다. 단 actomyosin의 superprecipitation에 대하여는 약간 촉진적(促進的)이었으나 이러한 작용은 actomyosin ATPase...
123.

골격근 Contractile Protein에 대한 Ca++의 영향

박찬웅(Park, C.W.), 정명희(Chung, M.H.), 오진섭(Oh, J.S.), 대한약리학회 대한약리학잡지 8 Pages

대한약리학회 대한약리학잡지 1972, 제 8권 제 2호 7 55-62 (8 pages)

박찬웅(Park, C.W.), 정명희(Chung, M.H.), 오진섭(Oh, J.S.), 저
...
- 3,000원
124.

Mitochondria의 Calcium Uptake에 미치는 Ouabain의 영향

홍사악(Hong, Sa-Ack), 박찬웅(Park, Chan-Woong), 김명석(Kim, Myung-Suk), 정명희(Chung, Myung-Hee), 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1972, 제 8권 제 1호 9 67-76 (10 pages)

홍사악(Hong, Sa-Ack), 박찬웅(Park, Chan-Woong), 김명석(Kim, Myung-Suk), 정명희(Chung, Myung-Hee), 저
...
- 3,000원
125.

Inositol 1,4,5-Trisphosphate-induced Increase in Ca2+-ATPase Activity in the Microsomes of Tracheal Epithelial Cells

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 9 269-278 (10 pages)

Cho, Hyoung-Jin, Park, Sung-Shin, Kim, Young-Kee 저
...
- 3,000원
Membrane vesicles were prepared by differential centrifugation from epithelial cells of porcine trachea. Total activity of microsomal ATPases was measured spectrophotometrically by a coupled enzyme assay. The steady-state activity of the enzyme was 329±10 nmol/min mg protein. Thapsigargin, a specific antagonist of intracellular Ca2+-ATPase, inhibited about 50% of the activity, leaving 178±18 nmol/min .mg protein (n=6), indicating that the Ca2+-ATPase is one of the major microsomal ATPases....
126.

Effects of Insulin and IGFS on Growth and Functional Differentiation in Primary Cultured Rabbit Kidney Proximal Tubule Cells -Growth and membrane transport-

Han, Ho-Jae, Park, Kwon-Moo, 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 2호 1 191-202 (12 pages)

Han, Ho-Jae, Park, Kwon-Moo, 저
...
- 4,100원
The purpose of this study was to compare effects of insulin and IGFs on growth, apical membrane enzyme activities and membrane transport systems of primary cultured rabbit kidney proximal tubule cells. Results were as follows: 1. Insulin and IGF-I produced significant growth stimulatory effects at 5 X 10-10M. IGF-II(5 X 10 -10 M) did not stimulate significant cell growth. 2. Insulin stimulated the phosphorylation of a 97 KD protein. It was difficult to determine whether this band represents...
127.

Inhibitory Effects of Verapamil and TMB-8 on Tonic Contraction Are Accompanied by Inhibition of Phospholipase C Activity in Intact Gastric Smooth Muscle Cells

Sim, Sang-Soo, Yoon, Shin-Hee, Hahn, Sang-June, Rhie, Duck-Joo, Jo, Yang-Hyeok, Kim, Myung-Suk 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 3 29-38 (10 pages)

Sim, Sang-Soo, Yoon, Shin-Hee, Hahn, Sang-June, Rhie, Duck-Joo, Jo, Yang-Hyeok, Kim, Myung-Suk 저
...
- 3,000원
Gastric smooth muscle of guinea pigs was used to investigate whether the inhibitory effect of calcium antagonists on tonic contraction was accompanied by inhibition of phospholipase C activity. Tonic contraction and [3H] inositol phosphate (IP) formation in response to acetylcholine were measured after pretreatment with verapamil, nifedipine, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxy-benzoate (TMB-8) or EGTA. Verapamil (10 μM), TMB-8 (10 μM) or EGTA (2 mM) significantly inhibited...
128.

Properties of Single K+ Channels of Skeletal Muscle Incorporated into Planar Lipid Bilayer

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 대한생리학회 대한생리학회지 16 Pages

대한생리학회 대한생리학회지 1995, 제 29권 제 1호 2 13-28 (16 pages)

Park, Jin-Bong, Kim, Hee-Jeong, Cho, Myung-Haing, Lee, Hang, Park, Hong-Ki, Lee, Mun-Han, Ryu, Pan-Dong 저
...
- 4,500원
single K+ channels of skeletal muscle from the rat and frog were into planar lipid bilayers and their properties were studied. Fusion was induced by an osmotic gradient. Of the four types of K+ channels recorded, the two most frequently observed were a voltage and Ca2+-activated K+ channel and a K+ channel with a prominent conductance substate. The first K+ channel was identified as the large Ca2+-activated K+ (BK) channel because the open-state probability was increased with depolarization...
129.

Calcium Current in the Unfertilized Egg of the Hamster

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 2호 12 215-224 (10 pages)

Haan, Jae-Hee, Cho, Soo-Wan, Yang, Young-Sun, Park, Young-Geun, Park, Hong-Gi, Chang, Gyeong-Jae, Kim, Yang-Mi, Park, Choon-Ok, Hong, Se 저
...
- 3,000원
The presence of a calcium current (iCa2+) passed via a specific channel was examined in the unfertilized hamster egg using the whole-cell voltage clamp technique. Pure inward current was isolated using a Ca2+-rich pipette solution containing 10 mM TEA. This current was independent of external Na+ and was highly sensitive to the Ca2+ concentration in the bathing solution, indicating that the inward current is carried by Ca2+. The maximal amplitude was -4.12±0.58nA (n=12) with 10mM Ca2+ at -3OmV...
130.

Production and Characterization of Specific Antibodies to Bombesin

Kwon, Hyeok-Yil, Lee, Yun-Lyul, Park, Hyoung-Jin 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1994, 제 28권 제 1호 9 91-98 (8 pages)

Kwon, Hyeok-Yil, Lee, Yun-Lyul, Park, Hyoung-Jin 저
...
- 3,000원
a coupling agent. The antisera were characterized by analysis of Scatchard and Sips plots. The antiserum LBE 2G/2 raised by repeat injection of the immunogen conjugated with carbodiimide showed the titer of 1 : 188,000, very low cross-reactivity to bombesin-like peptides except bombesin, with high affinity constant (1.64 X 1011 M-1) and high heterogeneity index (0.91). The antiserum LBG 1G/2 produced by repeat injection of the immunogen conjugated with glutaraldehyde possessed the titer of 1 :...

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