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121.

Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells

Yeo-MinLee, HeeJungKim, SunHwaHong, Myung-JunKim, DoSikMin, Duck-Joo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 9 57-63 (7 pages)

Yeo-MinLee, HeeJungKim, SunHwaHong, Myung-JunKim, DoSikMin, Duck-Joo 저
...
- 3,000원
Fluoxetine, a widely used anti-depressant compound, has several additional effects, including blockade of voltage-gated ion channels. We examined whether fluoxetine affects ATP-induced calcium signaling in PC12 cells by using fura-2-based digital calcium imaging and assay for [3H]-inositol phosphates (IPs). Treatment with ATP (100μM) for 2 min induced [Ca2⁢]i increases. The ATP-induced [Ca2⁢]i increases were significantly decreased by removal of extracellular Ca2⁢ and...
122.

Effect of Amrinone, a Selective Inhibitor of Phosphodiesterase III, on PMNs-induced

ByungKwonOh, HyoungKiKim, SooRanChoi, JinHoSong, EonSubPark, Byung 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 7 43-50 (8 pages)

ByungKwonOh, HyoungKiKim, SooRanChoi, JinHoSong, EonSubPark, Byung 저
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- 3,000원
reperfusion, significantly improved coronary flow, left ventricular developed pressure (P＜0.001), and the maximal rate of development of left ventricular developed pressure (P＜0.001), compared with ischemic/reperfused hearts perfused with PMNs in the absence of amrinone. In addition, amrinone significantly reduced myeloperoxidase activity by 50.8%, indicating decreased PMNs infiltration (p＜0.001). Superoxide radical and hydrogen peroxide production were also significantly reduced in fMLP- and...
123.

A Simple and Sensitive Assay for Cefepime in Human Plasma Using High Performance Liquid Chromatography

Young-SunKim, Dong-SeokYim, Dong-GunLee, Sang-BokLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.4 9 247-250 (4 pages)

Young-SunKim, Dong-SeokYim, Dong-GunLee, Sang-BokLee 저
...
- 1,500원
with perchloric acid. The extract was injected into an Atlantis dC18 column (250⁓4.6 mm; particle size 5μm, Waters) and the column was eluted with methanol and 0.01 M dihydrogen phosphate at pH 3.0 (15：85 v：v) as a mobile phase at a flow rate of 0.7 mL/min. Linearity was confirmed for the range 0.25 to 200μL/mL and the limit of quantitation was 0.25μL/mL. The retention times were 10.2 min and 13.4 min for cefepime and cefadroxil, respectively. This method was successfully applied to a...
124.

Changes in Vestibular Nerve Activity Following Acute Hypotension in Rats

ByungRimPark, MinSunKim, GueHyunYee, MyoungJinMoon, JaeHyoKim, YuanZheJin, YoSikKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.2 6 85-89 (5 pages)

ByungRimPark, MinSunKim, GueHyunYee, MyoungJinMoon, JaeHyoKim, YuanZheJin, YoSikKim 저
...
- 1,500원
The basic mechanism for the excitation of the peripheral vestibular receptors following acute hypotension induced by sodium nitroprusside (SNP) or hemorrhage was investigated in anesthetized rats. Electrical activity of the afferent vestibular nerve was measured after pretreatment with kynurenic acid, an NMDA receptor antagonist. The activity of the vestibular nerve at rest following acute hypotension induced by SNP or simulating hemorrhage was a greater increase than in control animals. The...
125.

Effect of Propofol, an Intravenous Anesthetic Agent, on KATP Channels of Pancreatic β-cells in Rats

EunJeePark, Dae-KyuSong, JaeKyuCheun, JungInBae, Won-KyungHo, YungEEarm 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.1 4 25-31 (7 pages)

EunJeePark, Dae-KyuSong, JaeKyuCheun, JungInBae, Won-KyungHo, YungEEarm 저
...
- 3,000원
membrane patches using the patch-clamp technique. In the inside-out configuration bath-applied propofol inhibited the KATP channel activities in a dose-dependent manner. The half-maximal inhibition dose (ED50) was 48.6⁑8.4μM and the Hill coefficient was 0.73⁑0.11. Single channel conductance calculated from the slope of the relationship between single channel current and pipette potential (⁢20∼⁢100 mV) was not significantly altered by propofol (control: 60.0⁑2.7...
126.

Effects of Carnosine and Related Compounds on Monosaccharide Autoxidation and H2O2 Formation

BeomJunLee, KyungSunKang, SangYoonNam, JaeHakPark, YongSoonLee, YoungWonYun, MyungHaingCho 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 3 251-261 (11 pages)

BeomJunLee, KyungSunKang, SangYoonNam, JaeHakPark, YongSoonLee, YoungWonYun, MyungHaingCho 저
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- 4,000원
The effects of carnosine and related compounds (CRCs) including anserine, homocarnosine, histidine, and β-alanine on monosaccharide autoxidation and H2O2 formation were investigated. The incubation of CRCs with D-glucose, D-glucosamine, and D, L-glyceraldehyde at 37oC increased the absorption maxima at 285 nm, 273 nm, and 290∼330 nm, respectively. D, L-glyceraldehyde was the most reactive sugar with CRCs. The presence of copper strongly stimulated the reaction of carnosine and anserine with...
127.

Role of Intracellular Taurine in Monensin-induced Na+, Ca++ Accumulation and Mechanical Dysfunction in Isolated Rat Hearts

Young-hoonKim, Jong-wanPark, Myung-sukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.5 9 537-546 (10 pages)

Young-hoonKim, Jong-wanPark, Myung-sukKim 저
...
- 3,000원
It has been postulated that the intracellular taurine is co-transported with Na⁢ down a concentration gradient and prevents the intracellular accumulation of sodium. It is therefore, expected that an elevated level of intracellular taurine prevents the sodium-promoted calcium influx to protect the cellular damages associated with sodium and calcium overload. In the present study, we evaluated the effects of intra- and extracellular taurine on the myocardial Na⁢ and Ca⁢⁢...
128.

항정신병 약물 비복용 정신분열증 환자의 99m-Tc-ECD SPECT로 측정한 국소뇌혈류량과 증상과의 관계

안석균, 전덕인, 이종두, 민성길 대한신경정신의학회 신경정신의학 11 Pages

대한신경정신의학회 신경정신의학 1997, 제 36권 제 3호 3 433-443 (11 pages)

안석균, 전덕인, 이종두, 민성길 저
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- 4,000원
129.

폐경기 여성에서 에스트로젠 사용이 인지기능에 미치는 영향

김성엽, 기백석, 남범우, 이상훈 대한신경정신의학회 신경정신의학 7 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 1호 16 183-189 (7 pages)

김성엽, 기백석, 남범우, 이상훈 저
...
- 3,000원
연구목적： 치매가 아닌 폐경기 여성에서 에스트로젠이 인지기능에 미치는 영향을 조사하기 위해 에스트로젠 보충요 법을 받고 있는 군과 받지 않고 있는 군에서 인지기능검사를 시행하여 차이가 있는지 알아보았다. 방 법： 폐경기 여성 중 에스트로젠 사용군 15명과 비사용군 15명을 선택하여 K-BNT(Boston naming test, Korean version), SRT(Selective reminding test), 공통성 검사(similarity test)를 사용하여 인지기능의 차이를 알아보려고 하였다. 더불어 BDI(Beck depression inventory)를 이용하여 우울에 미치는 영향도 함 께...
130.

노인정신장애 평가척도(Psychogeriatric Assessment Scale)의 한국판 표준화 연구

조맹제, 박임순, 신영민, 김무진, 정희연, 정은기, 최용성, 조성진, 서국희, 함봉진 대한신경정신의학회 신경정신의학 14 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 1호 12 128-141 (14 pages)

조맹제, 박임순, 신영민, 김무진, 정희연, 정은기, 최용성, 조성진, 서국희, 함봉진 저
...
- 4,300원
연구목적： 본 연구는 치매와 우울증을 다차원적으로 평가할 수 있는 도구인 Psychogeriatric Assessment Scale (PAS)의 한국판(PAS-K)을 개발하기 위한 것이다. 방 법： 번역, 역번역, 그리고 세차례의 예비조사를 통하여 PAS-K를 제작하였다. 60세 이상의 노인 291명(임상 환자군：58명, 지역사회노인군：168명, 수용시설 거주자：67명)과 그들의 정보제공자들을 대상으로 PASK, Geriatric Depression Scale(GDS), Korean version of Mini-Mental State Examination(MMSE-K), Hamilton Rating Scale for Depression(HRSD), 그리고...

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