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161.

Standard Error of Empirical Bayes Estimate in NONMEMⰒ VI

DongwooKang, Kyun-SeopBae, BrettE.Houk, RadojkaM.Savic, MatsO.Karlsson 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.2 3 97-106 (10 pages)

DongwooKang, Kyun-SeopBae, BrettE.Houk, RadojkaM.Savic, MatsO.Karlsson 저
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- 3,000원
The pharmacokinetics/pharmacodynamics analysis software NONMEMⰒ output provides model parameter estimates and associated standard errors. However, the standard error of empirical Bayes estimates of inter-subject variability is not available. A simple and direct method for estimating standard error of the empirical Bayes estimates of inter-subject variability using the NONMEMⰒ VI internal matrix POSTV is developed and applied to several pharmacokinetic models using intensively or...
162.

Intrinsic Gating in Inward Rectifier Potassium Channels (Kir2.1) with Low Polyamine Affinity Generated by Site Directed Mutagenesis

ISo, , IAshmole, HSoh, CSPark, PJSpencer, MLeyl, PRStanfield, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 3 131-142 (12 pages)

ISo, , IAshmole, HSoh, CSPark, PJSpencer, MLeyl, PRStanfield, 저
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- 4,100원
We have studied mutant forms of Kir2.1 in which an aspartate residue (D172), important for gating by intracellular polyamines, is replaced by one of three basic residues (Arg, Lys or His). Such channels are highly selective for K+, but show inward rectification that is a shallow function of voltage compared with that found in wild type. This inward rectification occurs with a reduced affinity for spermine and persists in the absence of polyamines. Though the unitary current-voltage relation...
163.

항정신병 약물치료하에서 주관적 안녕감을 평가하는 한국형 척도의 개발

윤진상, 국승희, 이형영, 이철, 백인호 대한신경정신의학회 신경정신의학 12 Pages

대한신경정신의학회 신경정신의학 2000, 제 39권 제 6호 2 987-998 (12 pages)

윤진상, 국승희, 이형영, 이철, 백인호 저
...
- 4,100원
연구목적： 본 연구의 목적은 1994년 Naber등이 개발한 38문항의‘항정신병 약물치료하에서 주관적 안녕감을 평가 하는 자가평정척도(a self-rating scale to measure subjective well-being under neuroleptic treatment： SWN)’를 문항수를 줄이고 문항내용을 수정하여 한국형으로 개발하고자 하였다. 방 법： 204명의 정신분열병 환자들에게 22문항의 KmSWN과 General Health Questionnaire/Quality of Life- 12(GHQ/QL-12)를 실시하였고, 사회인구학적 및 임상적 특징을 조사하였다. 자료분석에는 척도에 대한 반 응과 정보가...
164.

청소년 인터넷 중독 성향과 관련된 사회 인구학적 특성과 정서 및 행동상의 요인

김남희, 신윤미, 조선미, 이영문, 임기영, 정영기, 김수권, 최지순 대한신경정신의학회 신경정신의학 6 Pages

대한신경정신의학회 신경정신의학 2008, 제 47권 제 4호 9 378-383 (6 pages)

김남희, 신윤미, 조선미, 이영문, 임기영, 정영기, 김수권, 최지순 저
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- 3,000원
165.

입원한 학업중단 청소년 정신질환자에 관한 정신의학적 연구

신용규, 박두병, 이길홍 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1994, 제 33권 제 6호 10 1295-1303 (9 pages)

신용규, 박두병, 이길홍 저
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- 3,000원
166.

청반핵 자극으로 인한 노르아드레날린의 유리가 동통의 조절에 미치는 영향

박경표(Kyung-Pyo Park), 김종성(Jong Sung Kim), 서대철(Dae Chul Suh), 박형섭(Hyoung-Sup Park) 대한약리학회 대한약리학잡지 10 Pages

대한약리학회 대한약리학잡지 1994, 제 30권 제 1호 4 29-38 (10 pages)

박경표(Kyung-Pyo Park), 김종성(Jong Sung Kim), 서대철(Dae Chul Suh), 박형섭(Hyoung-Sup Park) 저
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- 3,000원
배외측 뇌교의 전기자극은 척수 수준에서 동통의 역치를 증가시키고, 또한 말초로 부터 오는 유해성 자극에 의해 야기되는 척수후각세포의 흥분성을 억제하여 진통효과를 나타낸다. 이러한 진통효과는 noradrdnergic 원심신경을 매개로 한다고 하였지만, 이직까지 이를 직접적으로 뒷받침하는 신경화학적인 증거는 보고되지 않았다. 따라서 본 실험은 뇌교에 위치한 청반핵(Locus coeruleus)의 전기자극시, 척수 수준에서 일어나는 동통조절효과를 쥐꼬리 회피 반사(Tail Flick Reflex)를 이용해 관찰하고, 이러한 동통조절효과는 어떤...
167.

Induction of Drought Stress Resistance by Multi-Functional PGPR Bacillus Licheniformis K11 in Pepper

한국식물병리학회 The Plant Pathology Journal 8 Pages

한국식물병리학회 The Plant Pathology Journal 2013, 29권 2호 10 201-208 (8 pages)

저
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- 3,000원
Drought stress is one of the major yield affecting factor for pepper plant. The effects of PGPRs were analyzed in relation with drought resistance. The PGPRs inoculated pepper plants tolerate the drought stress and survived as compared to non-inoculated pepper plants that died after 15 days of drought stress. Variations in protein and RNA accumulation patterns of inoculated and noninoculated pepper plants subjected to drought conditions for 10 days were confirmed by two dimensional...
168.

The First Identified Citrus tristeza virus Isolate of Turkey Contains a Mixture of Mild and Severe Strains

한국식물병리학회 The Plant Pathology Journal 11 Pages

한국식물병리학회 The Plant Pathology Journal 2013, 29권 1호 4 31-41 (11 pages)

저
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- 4,000원
The presence of Citrus tristeza virus (CTV) has previously been reported in citrus growing regions of Turkey. All serologically and biologically characterized isolates including I d r, which was the first identified CTV isolates from Turkey, were considered mild isolates. In this study, molecular characteristics of the I d r isolate were determined by different methods. Analysis of the I d r isolate by western blot and BD-RT-PCR assays showed the presence of MCA13 epitope, predominantly found in...
169.

Difference of Physiochemical Characteristics Between Citrus Bacterial Canker Pathotypes and Identification of Korean Isolates with Repetitive Sequence PCRs

한국식물병리학회 The Plant Pathology Journal 10 Pages

한국식물병리학회 The Plant Pathology Journal 2008, 24권 4호 8 423-432 (10 pages)

저
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- 3,000원
The difference of carbon source utilization and fatty acid composition between the pathotypes of Xanthomonas strains, which causing citrus bacterial canker was compared, and the physiochemical characteristics were used to analyze relationship of the strains for the first time. The pattern of several carbon sources utilization and fatty acids composition reliably discriminated the pathotypes of Xanthomonas strains. The dendrogram which was constructed by 95 carbon source utilization profiles...
170.

Syntactic Difficulties in Children with Specific Language Impairment (SLI); why do they have difficulties in complex sentences and what are the intervention options?

Dong Sun Yim 이화여자대학교 교과교육연구소 Eastwest Education 17 Pages

이화여자대학교 교과교육연구소 Eastwest Education 2013, Vol.30 1 1-17 (17 pages)

Dong Sun Yim 저
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- 4,600원
The purpose of this tutorial is to provide speech-language pathologists(SLPs) with updated general information regarding language intervention techniques for children with syntactic language impairment. This clinical resource was compiled to support SLPs who need to understand the functions and effects of diverse interventions available for children with syntactic language impairment. Intervention studies have demonstrated that treatment of these deficits is indeed effective, and to date, the...

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