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Classical natural ovine scrapie prions detected in practical volumes of blood by lamb and transgenic mouse bioassays
Rohana P. Dassanayake, Thomas C. Truscott, Dongyue Zhuang, David A. Schneider, Sally A. Madsen-Bouterse, Alan J. Young, James B. 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2015, 제 16권 제 2호 7 179-186 (8 pages)
Scrapie is diagnosed antemortem in sheep by detecting misfolded isoforms of prion protein (PrP) in lymphoid follicles of the rectal mucosa and nictitating membranes. Assay sensitivity is limited if (a) the biopsy is collected early during disease development, (b) an insufficient number of follicles is collected, or (c) peripheral accumulation of PrP is reduced or delayed. A blood test would be convenient for mass live animal scrapie testing. Currently approved techniques, however, have their own... -
Development of a multiplex loop-mediated isothermal amplification assay to detect shiga toxin-producing Escherichia coli in cattle
Hee-Jin Dong, Ae-Ri Cho, Tae-Wook Hahn, Seongbeom Cho* 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 2호 19 317-325 (9 pages)
samples by conventional selective culture, immunomagnetic separation, and PCR-based culture methods, respectively. The coinciding multiplex PCR and mLAMP results for the types of shiga toxin revealed the value of the mLAMP assay in terms of accuracy and rapidity for characterizing shiga toxin genes. Furthermore, the high detection rate of specific genes from enrichment broth samples indicates the potential utility of this assay as a screening method for detecting STEC in cattle farm samples. -
Production of a highly group-specific monoclonal antibody against zearalenone and its application in an enzyme-linked immunosorbent assay
Sang-Ho Cha, Sung-Hee Kim, Karyn Bischoff, Hyun-Jeong Kim, Seong-Wan Son, Hwan-Goo Kang* 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 2호 2 119-125 (7 pages)
ELISA systems using the selected antibody (ZEN-coated and anti-ZEN antibody-coated ELISA). Quantitative ranges for the anti-ZEN antibody-coated ELISA and ZEN-coated ELISA were from 25 to 750 ppb and from 12.5 to 100 ppb, respectively. The detection limit of both methods as measured with standard solutions was 10 ppb. The intra-plate and inter-well variation of both ELISAs were less than 10%. The IC50 values for a-zearalenol, b-zearalenol, a-zearalanol, and b-zearalanol compared to ZEN were 108.... -
Sequence and phylogenetic analysis of the gp200 protein of Ehrlichia canis from dogs in Taiwan
Chia-Chia Huang, Yu-Chen Hsieh, Chau-Loong Tsang, Yang-Tsung Chung* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2010, 제 11권 제 4호 9 333-340 (8 pages)
E. canis Taiwanese genotype was genetically distinct from other reported isolates obtained from the United States, Brazil, and Israel, and that it formed a separate clade. Remarkable variations unique to the Taiwanese genotype were found throughout the deduced amino acid sequence of gp200, including 15 substitutions occurring in two of five known species-specific epitopes. The gp200 amino acid sequences of the Taiwanese genotype bore 94.4∼94.6 identities with those of the isolates from the... -
Application of biotechnological tools for coccidia vaccine development
Wongi Min, Rami A. Dalloul, Hyun S. Lillehoj 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 1 279-288 (10 pages)
in the development of a practical and effective control strategy against Eimeria and design of nutritional interventions to maximize growth under the stress caused by vaccination or infection. Furthermore, successful identification of quantitative economic traits associated with disease resistance to coccidiosis will provide poultry breeders with a novel selection strategy for development of genetically stable, coccidiosis-resistant chickens, thereby increasing the production efficiency. -
Lack of bioequivalence of two oxytetracycline formulations in the rabbit
Y. J. Kim, W. Chong, S. D. Kim, S. K. Han, P. D. Ryu 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 1호 5 25-30 (6 pages)
Oxytetracycline (OTC) has been used for over 40 years in veterinary medical field. Various forms of oxytetracycline preparations have been marketed, but little information is available on the bioequivalence of OTC preparations. This study was conducted to evaluate the bioequivalence of two OTC powder preparations available in Korea. Fourteen rabbits were randomly allocated into two groups. During the first period, a dose (200 mg/kg) of reference product was orally administered to the rabbits in... -
Physiology,Chemistry,Pharmacology,Toxicology : Residual determination of Ceftiofur in Raw Bovine Milk by Liquid Chromatography-Electrospray Mass Spectrometry
JongHwanLim, ByungKwonPark, MyoungSeokKim, BeomSuJang, DooKim, HyoInYun 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 5 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2004, 제 44권 제 3호 7 367-371 (5 pages)
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물질문화의 유형과 고고학 분석의 단위 - 한국 청동기시대 유형론을 중심으로
성춘택, 문수균, 양혜민 한국고고학회 한국고고학보 32 Pages
한국고고학회 한국고고학보 2018, 제 109집 10 326-357 (32 pages)
고고학은 과거 물질 자료의 패턴을 찾고자 속성에서 유형, 문화에 이르기까지 일련의 위계적 분석 단위를 사용한다. 유물에서 관찰 및 측정 가능한 최소 단위가 속성이고, 한 유적이나 층에서 나온 유물이 모여 유물복합체를 이루며, 특정 시공간의 유물복합체의 패턴을 바탕으로 유형을 설정한다. 이 과정에서고고학자는 흔히 특정 속성이나 유물을 전형으로 삼아 더 높은 분석 단위를 정의한다. 그러나 고고 자료는 토기와 석기, 주거지, 무덤 등 여러 서로 다른 차원의 유구와 유물이 중층적으로 얽힌 조합이다. 따라서 지나치게 특정... -
습관 장애가 동반된 주의력결핍/과잉운동장애 아동에서의 구안파신 약물 효과에 대한 예비연구
Youngshin Kim, Lawrence Scahill, James Leckman 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 5호 11 908-919 (12 pages)
연구목적： 주의력결핍/과잉운동장애(이하 ADHD)와 틱장애는 소아기에 발생하는 흔한 신경정신과 질환이며 또한 두 장애는 자주 같이 동반되어 나타나는 질환이다. ADHD에서의 중추신경자극제의 효능은 이미 잘 알려져 있지 만 약 25%의 ADHD 환자는 이 계통의 약물에 효과가 없거나 틱의 악화를 포함한 심각한 부작용으로 중추 신경자극제 약물치료를 할 수 없다. 선택적 α2A 효현제인 guanfacine이 최근에 ADHD 아동의 치료에 도입 되어 사용되고 있다. 이 연구는 ADHD와 습관장애가 공존하는 아동에서 guanfacine의 효능과 안정성을... -
Response of Barley Genotypes to Fusarium Head Blight under Natural Infection and Artificial Inoculation Conditions
Raja Khanal, Thin Meiw Choo, Allen G. Xue, Bernard Vigier, Marc E. Savard, Barbara Blackwell, Junmei Wang, Jianming Yang, Richard A. Martin 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 5호 5 455-464 (10 pages)
across 5 years at Harrington, Prince Edward Island. These genotypes were also evaluated for Fusari- um head blight (FHB) severity and DON concentration under field nurseries with artificial inoculation of Fusarium graminearum by the grain spawn method across 2 years at Ottawa, Ontario, and one year at Hangzhou, China. Additionally, these genotypes were also evaluated for FHB severity under greenhouse conditions with artificial inoculation of F. graminearum by conidial suspension spray method...
