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Ca2+-activated K+ Currents of Pancreatic Duct Cells in Guinea-pig
Han-WookLee, JingchaoLi, Na-YounKoo, ZhengGenPiao, SungMinHwang, Jae-WoongHan, Han-SaemChoi, Jong-HeunLee, JoongSooKim, KyungpyoPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 4 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.6 7 335-338 (4 pages)
There are numerous studies on transepithelial transports in duct cells including Cl and/or HCO3. However, studies on transepithelial K transport of normal duct cells in exocrine glands are scarce. In the present study, we examined the characteristics of K currents in single duct cells isolated from guinea pig pancreas, using a whole-cell patch clamp technique. Both Cl and K conductance were found with KCl rich pipette solutions. When the bath solution... -
Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes
Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 3 83-88 (6 pages)
The purpose of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used... -
Effects of Chlorhexidine Digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic Acid in Porphyromonas ginginvalis Outer Membranes
Hye-OckJang, Seong-KweonCha, ChangLee, Min-GakChoi, Sung-RyulHuh, Sang-HunShin, In-KyoChung, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2003, Vol.7 No.3 2 125-130 (6 pages)
The aim of this study was to provide a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine the effect of chlorhexidine digluconate on differential rotational mobility of different positions of the number of membrane bilayer phospholipid carbon atoms. The six membrane components differed with respect to 2, 3, 6, 9, 12, and 16-(9-anthroyloxy)stearic acid (2-AS, 3-AS, 6-AS,... -
Phytoestrogen-Induced Phosphorylation of MAP Kinase in Osteoblasts is Mediated by Membrane Estrogen Receptor
YounHeePark, HwanKiPark, HyoJinLee, SunMuPark, SangWonChoi, WonJungLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.3 7 165-170 (6 pages)
We have previously demonstrated that phytoestrogens isolated from safflower seeds significantly attenuated bone loss in ovariectomized rats, and directly stimulated proliferation and differentiation of cultured osteoblastic cells. In an attempt to elucidate underlying cellular mechanisms, in the present study we investigated effects of 17β-estradiol (E2) and phytoestrogens such as matairesinol and acacetin, a type of lignan and flavonoid, respectively, on activation of mitogen activated... -
Nitroxergic Nerve Relaxes Rat Gastric Smooth Muscle by NO-cGMP Pathway
YoongSamYoon, HyoungChulChoi, YoungSookJung, JongHoKim, KwangYounLee, UyDongSohn, JeoungHeeHa, WonJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 5 369-378 (10 pages)
This study was undertaken to investigate an involvement of nitroxergic innervation in gastric smooth muscle of rat. Isometric tension study, the measurement of single cell length, NADPH diaphorase stain of smooth muscle layers and neuronal nitric oxide synthase (nNOS) western blotting were performed. Sodium nitroprusside (SNP), a nitric oxide donor, relaxed the muscle strips precontracted by acetylcholine (ACh) in a concentration-dependent manner. Pretreatment of L-arginine decreased the... -
Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. II. Inhibitory Effects of ANG II on Na+ Uptake
HoJaeHan, SooHyunPark, HyunJuKoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 9 425-434 (10 pages)
Many reports represent that angiotensin II (ANG II) caused a dose dependent biphasic effects on fluid transport in the proximal tubule. However, respective roles of different signaling pathways in mediating these effects remain unsettled. The aim of the present study was to examine signaling pathways at high doses of ANG II on the Na+ uptake of primary cultured rabbit renal proximal tubule cells(PTCs) in hormonally defined serum-free medium. High concentrations of ANG II (>10-9 M) inhibited... -
Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. I. Stimulatory Effects of ANG II on Na+ Uptake
HoJaeHan, HyunJuKoh, SooHyunPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 8 413-423 (11 pages)
The importance of the kidney in the development of hypertension was first demonstrated by Goldblatt and his colleagues more than fifty years ago. Many hormones and other regulatory factors have been proposed to play a major role in the development of hypertension. Among these factors angiotensin II (ANG II) is closely involved in renal hypertension development since it directly regulates Na+ reabsorption in the renal proximal tubule. Thus the aim of the present study was to examine signaling... -
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흰쥐 말초 혈액 림프구의 분자량 44 kD 단백의 인산화
안영수(Young Soo Ahn), 주일로(I-Lo Jou), 오도연(Do Yeun Oh), 임승욱(Seung Wook Lim), 박경선(Kyung Sun Park) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1991, 제 27권 제 2호 6 135-144 (10 pages)
흰쥐 말초혈액에서 얻은 T 림프구를 아드레날린성 β-수용체 효현제 및 concanavalin A(Con-A)로 자극해 다음과 같은 결과를 얻었다. 자극이 없는 상태에서의 주 인산화 단백은 분자량 44kD, 등전점 6.8의 단백이었으며 효현제로 자극시키면 분자량 44kD, 등전점 6.3의 단백이 새로이 인산화되어 나타났다. 이 분자량 44kD, 등전점 6.3의 단백은 forskolin에 의해 역시 인산화되며 A-kinase 억제제인 H-8을 전처치하면 인산화의 억제가 나타났다. 또한 Con-A로 자극시키면 44 kD/pI 6.3 단백의 인산화가 증가되었으며 이 인산화의 증가는... -
육군 사관생도의 에너지소비량 및 영양섭취량에 관한 연구
조태호(Cho, T.H.) 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1967, 제 1권 제 1호 13 121-134 (14 pages)


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