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301.

PAF Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury through Neutrophilic Oxidative Stress

YoungManLeeYoon-yubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 5 405-414 (10 pages)

YoungManLeeYoon-yubPark 저
...
- 3,000원
The role of platelet-activating factor (PAF) was investigated in intestinal ischemia/reperfusion (I/R) induced acute lung injury associated with oxidative stress. To induce acute lung injury following intestinal I/R, superior mesenteric arteries were clamped with bulldog clamp for 60 min prior to the 120 min reperfusion in Sprague-Dawley rats. Acute lung injury by intestinal I/R was confirmed by the measurement of lung leak index and protein content in bronchoalveolar lavage (BAL) fluid. Lung...
302.

Effect of the Inhibition of Phospholipase A2 in Generation of Free Radicals in Intestinal Ischemia/Reperfusion Induced Acute Lung Injury

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 4 263-273 (11 pages)

YoungManLee, Yoon-yubPark, TeoanKim, HyunG.Cho, YoonJeongLee, JohnE.Repine 저
...
- 4,000원
The role of phospholipase A2 (PLA2) in acute lung leak induced by intestinal ischemia was investigated in association with neutrophilic respiratory burst. To induce lung leak, we generated intestinal ischemia for 60 min prior to the 120 min reperfusion by clamping superior mesenteric artery in Sprague-Dawley rats. Acute lung leak was confirmed by the increased lung leak index and protein content in bronchoalveolar fluid. These changes were inhibited by mepacrine, the non-specific PLA2...
303.

The Roles of Arachidonic Acid and Calcium in the Angiotensin II-induced Inhibition of Na+ Uptake in Renal Proximal Tubule Cells

SooHyunPark, HyunJooKoh, YeunHeeLee, ChangHoSon, MinKyoungPark, YoungJaeLee, HoJaeHan 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 11 83-91 (9 pages)

SooHyunPark, HyunJooKoh, YeunHeeLee, ChangHoSon, MinKyoungPark, YoungJaeLee, HoJaeHan 저
...
- 3,000원
Angiotensin II (ANG II) has a biphasic effect on Na⁢ transport in proximal tubule: low doses of ANG II increase the Na⁢ transport, whereas high doses of ANG II inhibit it. However, the mechanisms of high dose ANG II-induced inhibition on Na⁢ uptake are poorly understood. Thus the aim of the present study was to investigate signal transduction pathways involved in the ANG II-induced inhibition of Na⁢ uptake in the primary cultured rabbit renal proximal tubule cells (PTCs)...
304.

Simultaneous HPLC Analysis of Arachidonic Acid Metabolites in Biological Samples with Simple Solid Phase Extraction

Hyung-GunKim, Young-NaHuh, Kun-SukPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.6 15 779-786 (8 pages)

Hyung-GunKim, Young-NaHuh, Kun-SukPark 저
...
- 3,000원
A reversed-phase high-performance liquid chromatogrphy (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram level. This procedure makes it possible to extract complex mixtures of eicosanoids efficiently with a single step and to analyze them simultaneously by RP-HPLC from biological samples using octadesylsilyl silica extraction column and PGB2 as an internal...
305.

Effect of the Inhibition of PLA2 on Oxidative Lung Injury Induced by Interleukin-1㄁

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 10 617-628 (12 pages)

YoungManLee, HyunGugCho, Yoon-YubPark, Jong-KiKim, YoonJeongLee, Won-HarkPark, TeoanKim 저
...
- 4,100원
In order to understand the pathogenetic mechanism of adult respiratory distress syndrome (ARDS), the role of phospholipase A2 (PLA2) in association with oxidative stress was investigated in rats. Interleukin-1㄁ (IL-1, 50 ㄍg/rat) was used to induce acute lung injury by neutrophilic respiratory burst. Five hours after IL-1 insufflation into trachea, microvascular integrity was disrupted, and protein leakage into the alveolar lumen was followed. An infiltration of neutrophils was...
306.

Effect of the Inhibition of Platelet Activating Factor on Oxidative Lung Injury Induced by Interleukin-1α

YoungManLeeYoon-YubPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 13 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.4 10 479-491 (13 pages)

YoungManLeeYoon-YubPark 저
...
- 4,200원
In order to know the pathogenesis of adult respiratory distress syndrome (ARDS) in association with the oxidative stress by neutrophils, the role of platelet activating factor (1-0-alkyl-2-acetyl-sn- glycero-3-phosphocholine, PAF) was investigated during acute lung injury induced by interleukin- 1α (IL-1) in rats. An insufflation of IL-1 into the rat's trachea increased the acetyltransferase activity in the lung and the increase of PAF content was followed. As evidences of acute lung injury by...
307.

Regulatory Mechanisms of Angiotensin II on the Na+/H+ Antiport System in Rabbit Renal Proximal Tubule Cells. II. Inhibitory Effects of ANG II on Na+ Uptake

HoJaeHan, SooHyunPark, HyunJuKoh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages

대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1997, Vol.1 No.4 9 425-434 (10 pages)

HoJaeHan, SooHyunPark, HyunJuKoh 저
...
- 3,000원
Many reports represent that angiotensin II (ANG II) caused a dose dependent biphasic effects on fluid transport in the proximal tubule. However, respective roles of different signaling pathways in mediating these effects remain unsettled. The aim of the present study was to examine signaling pathways at high doses of ANG II on the Na+ uptake of primary cultured rabbit renal proximal tubule cells(PTCs) in hormonally defined serum-free medium. High concentrations of ANG II (＞10-9 M) inhibited...
308.

Iproniazid 및 Lithium이 가토 혈중주정농도에 미치는 영향에 관한 실험적 연구

정성덕 대한신경정신의학회 신경정신의학 9 Pages

대한신경정신의학회 신경정신의학 1973, 제 12권 제 4호 4 266-274 (9 pages)

정성덕 저
...
- 3,000원
309.

문화재 복원에 사용하는 접착재료의 유해성과 작업환경

장성윤, 조주혜 한국대학박물관협회 고문화 15 Pages

한국대학박물관협회 고문화 2017, 제90집 3 51-65 (15 pages)

장성윤, 조주혜 저
...
- 4,400원
이 연구는 문화재 복원에 사용되는 접착재료의 유해성을 검토하고 실제 현장에서 작업자에게 미칠 수 있는 영향을 분석하였다. 먼저 문화재 보존 현장에서 가장 많이 사용되는 접착제와 퍼티에 대한 설문조사 결과를 토대로 접착제 3종(Loctite 401, Cemedine C, Araldite rapid)과 퍼티 2종(CDK-520, Araldite SV427-2/HV427-1)을 대상재료로 선정하였다. 이들 접착제에서 방출되는 총 휘발성유기화합물의 양과 종류를 측정한 결과, 보존처리에 가장 널리 사용되는 Loctite 401이 가장 높은 함량을 나타냈고, 다음으로 Cemedine...
310.

흰쥐 원위세뇨관과 피질집합관의 산소소비량에 대한 Bradykinin의 영향

이석용(Seok-Yong Lee), 조규철(Kyu-Chul Cho) 대한약리학회 대한약리학잡지 6 Pages

대한약리학회 대한약리학잡지 1990, 제 26권 제 2호 8 161-166 (6 pages)

이석용(Seok-Yong Lee), 조규철(Kyu-Chul Cho) 저
...
- 3,000원
Kallikrein-kinin계는 신장의 혈류역학과 수분 및 전해질 배설의 조절자로서 역할을 하는 것으로 알려져 있다. Kallikrein-kinin계의 유효한 펩타이드중 하나인 bradykinin(BK)을 신동맥에 주입시 전해질 배설이 증가하는데 이 작용이 신혈류역학적 변동에 기인하는지 또는 신세뇨관의 전해질 운반에 대한 직접적인 작용에 기인하는지 아직 확실치 않다. 따라서 본 연구에서는 원위세뇨관(DT)과 피질집합관(CCT)에서의 전해질운반 의존성 산소소비에 대한 BK의 영향을 관찰하였다. BK(0.1μM)은 DT과 CCT의 산소소비를 유의하게...

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