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Mechanism of Pituitary Adenylate Cyclase-Activating Polypeptide- Induced Inhibition on Catecholamine Secretion Evoked by Cholinergic Stimulation and Membrane Depolarization in the Rat Adrenal Gland
Dong-YoonLim, Jeong-WonKang, Young-JoKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.3 12 339-350 (12 pages)
The present study was attempted to examine the effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on catecholamine (CA) secretion evoked by cholinergic stimulation, membrane depolarization and calcium mobilization from the isolated perfused rat adrenal gland. The perfusion of PACAP (10 nM) into an adrenal vein for 60 min produced a great inhibition in CA secretion evoked by ACh (5.32⁓103 M), high K (5.6⁓102 M), DMPP (104 M for 2 min),... -
Assessment of Flavin-containing Monooxygenase (FMO) Activity by Determining Urinary Ratio of Theobromine and Caffeine in a Korean Population after Drinking a Cup of Coffee
Woon-GyeChung, , Ju-HeeKang, Hyung-KeunRoh, Kyung-HoonLee, Chang-ShinPark, Young-NamCha, 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.2 11 207-213 (7 pages)
To examine individual variation in drug metabolism catalyzed by flavin-containing monooxygenase (FMO), 179 Korean volunteers' urinary molar concentration ratio of theobromine (TB) and caffeine (CA) was determined. Their urine was collected for 1 hr (between 4 and 5 hrs) after they drank a cup of coffee containing 115 mg CA and analyzed by an HPLC system. The lowest TB/CA ratio obtained was 0.40, the highest ratio was 15.17 (38-fold difference), and the median ratio for all subjects was 1.87.... -
Effect of K+-channel Blockers on the Muscarinic- and A1-adenosine- Receptor Coupled Regulation of Electrically Evoked Acetylcholine Release in the Rat Hippocampus
ByungSikYu, DoKyungKim, BongKyuChoi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.2 2 147-154 (8 pages)
It was attempted to clarify the participation of K+-channels in the post-receptor mechanisms of the muscarinic and A1-adenosine receptor- mediated control of acetylcholine (ACh) release in the present study. Slices from the rat hippocampus were equilibrated with [3H]choline and the release of the labelled products was evoked by electrical stimulation (3 Hz, 5 V/cm, 2 ms, rectangular pulses), and the influence of various agents on the evoked tritium-outflow was investigated. Oxotremorine (Oxo,... -
정신분열증 환자의 면역기능에 관한 연구 — T 및 B 임파구 아형의 갯수 및 백분율을 중심으로 ᅳ
남민, 조숙행, 곽동일 대한신경정신의학회 신경정신의학 14 Pages
대한신경정신의학회 신경정신의학 1992, 제 31권 제 3호 2 457-470 (14 pages)
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Indole, Indole-3-calbinol 및 Benzofuran이 간장 microsome과 cytosol의 약물대사 효소 활성도에 미치는 영향
차영남(Young-Nam Cha), 정진호(Jin-Ho Chung), David C. Thompson, Henry S. Heine 대한약리학회 대한약리학잡지 11 Pages
대한약리학회 대한약리학잡지 1985, 제 21권 제 1호 1 1-11 (11 pages)
이물질(xenobiotics) 대사에 관여하는 간장 microsome과 cytosol 효소 활성에 indole, indole-3-carbinol 및 benzofuran이 미치는 영향을 검색하기위하여 마우스에 이들 약물을 각각 5 mmole/kg씩 10일간 투여하여 다음 몇 가지의 성적을 얻었다. Benzofuran은 microsome 효소인 aniline hydroxylase, 7-ethoxycoumarin O-deethylase, p-nitrophenol UDPGA-transferase, epoxide hydrolase와 cytosol 효소인 glutathione S-tranferase, NADH : quinone reductase, UDP-glucose dehydrogenase의 활성도를 증가시켰다. 그러나... -
Inhibitory Effects of Verapamil and TMB-8 on Tonic Contraction Are Accompanied by Inhibition of Phospholipase C Activity in Intact Gastric Smooth Muscle Cells
Sim, Sang-Soo, Yoon, Shin-Hee, Hahn, Sang-June, Rhie, Duck-Joo, Jo, Yang-Hyeok, Kim, Myung-Suk 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1995, 제 29권 제 1호 3 29-38 (10 pages)
Gastric smooth muscle of guinea pigs was used to investigate whether the inhibitory effect of calcium antagonists on tonic contraction was accompanied by inhibition of phospholipase C activity. Tonic contraction and [3H] inositol phosphate (IP) formation in response to acetylcholine were measured after pretreatment with verapamil, nifedipine, 8-(N,N-diethylamino)octyl 3,4,5-trimethoxy-benzoate (TMB-8) or EGTA. Verapamil (10 μM), TMB-8 (10 μM) or EGTA (2 mM) significantly inhibited... -
Application of the Maryblyt Model for the Infection of Fire Blight on Apple Trees at Chungju, Jecheon, and Eumsung during 2015-2020
Mun-Il Ahn, Sung Chul Yun 한국식물병리학회 The Plant Pathology Journal 12 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 6호 5 543-554 (12 pages)
To preventively control fire blight in apple trees and determine policies regarding field monitoring, the Ma- ryblyt ver. 7.1 model (MARYBLYT) was evaluated in the cities of Chungju, Jecheon, and Eumseong in Korea from 2015 to 2020. The number of blossom infection alerts was the highest in 2020 and the lowest in 2017 and 2018. And the common feature of MARYBLYT blossom infection risks during the flowering period was that the time of BIR-High or BIR-Infection alerts was the same regardless of... -
Identification of strA-strB Genes in Streptomycin-Resistant Pseudomonas syringae pv. actinidiae Biovar 2 Strains Isolated in Korea
Young Sun Lee, Gyoung Hee Kim, Young Jin Koh, Jae Sung Jung 한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2021, 37권 5호 8 489-493 (5 pages)
Bacterial canker is a devastating disease of kiwifruit caused by the bacterium Pseudomonas syringe pv. ac- tinidiae. Canker disease of kiwifruit in Korea has been controlled using streptomycin for more than two de- cades. Four streptomycin-resistant strains, belonging to biovar 2, which are found only in Korea, were col- lected between 2013 and 2014 from different orchards located in Jeju, Korea. The genetic background for streptomycin resistance among P. syringe pv. actinidiae strains were... -
Suppression of Melanose Caused by Diaporthe citri on Citrus Leaves Pretreated with Bio-sulfur
Yong Ho Shin, Eun Ju Ko, Su Jeong Kim, He Nam Hyun, Yong Chull Jeun 한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2019, 35권 5호 3 417-424 (8 pages)
Melanose, caused by Diaporthe citri, is one of severe diseases in citrus, a major economic resource in Jeju island. To reduce the usage amount of organic synthetic fungicide, bio-sulfur was tested as an alternative chemical to control citrus melanose in the present study. Direct antifungal activity of bio-sulfur against D. citri was determined through in vitro experiment using artificial nutrient media. Disease severity of melanose on bio-sulfur pretreated citrus leaves was lower than that on... -
A Small GTPase RHO2 Plays an Important Role in Pre-infection Development in the Rice Blast Pathogen Magnaporthe oryzae
Teng Fu, Joon-Oh Kim, Joon-Hee Han, Adiyantara Gumilang, Yong-Hwan Lee, Kyoung Su Kim 한국식물병리학회 The Plant Pathology Journal 10 Pages
한국식물병리학회 The Plant Pathology Journal 2018, 34권 6호 2 470-479 (10 pages)
The rice blast pathogen Magnaporthe oryzae is a global threat to rice production. Here we characterized RHO2 gene (MGG_02457) that belongs to the Rho GTPase family, using a deletion mutant. This mutant ΔMorho2 exhibited no defects in conidiation and germination but developed only 6% of appressoria in response to a hydrophobic surface when compared to the wild-type progenitor. This result indicates that MoRHO2 plays a role in appressorium development. Furthermore, exogenous cAMP treatment on the...


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