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총 182건 검색
본문검색 결과만 보기
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Effect of 5-FU and MTX on the Expression of Drug-resistance Related Cancer Stem Cell Markers in Non-small Cell Lung Cancer Cells
HeeYi, Hee-JungCho, Soo-MinCho, KyulJo, Jin-APark, Soo-HanLee, Byung-JoonChang, Jin-SukKim, Ho-ChulShin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 2 11-16 (6 pages)
of drug-resistance related stem-cell surface markers, such as CD133 and ABCG2. Recently, we reported that CSCs have a high level of expression of the IL-6 receptor (IL-6R). The purpose of this study was to investigate the effect of anticancer drugs on the expression of the drug resistance-related cancer stem cell markers, ABCG2, IL-6R, and CD133 in non-small cell lung cancer (NSCLC) cell lines. A549, H460, and H23 NSCLC cell lines were treated with the anticancer drugs 5-fluorouracil (5-FU; 25... -
Role of Two Sets of RND-Type Multidrug Efflux Pump Transporter Genes, mexAB-oprM and mexEF-oprN, in Virulence of Pseudomonas syringae pv. tabaci 6605
Yuki Ichinose, Takafumi Nishimura, Minori Harada, Ryota Kashiwagi, Mikihiro Yamamoto, Yoshiteru Noutoshi, Kazuhiro Toyoda, Fumiko Taguchi, Daigo Takemoto, Hidenori Matsui 한국식물병리학회 The Plant Pathology Journal 9 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 2호 4 148-156 (9 pages)
Pseudomonas syringae pv. tabaci 6605 has two mul- tidrug resistance (MDR) efflux pump transporters, MexAB-OprM and MexEF-OprN. To understand the role of these MDR efflux pumps in virulence, we generated deletion mutants, ∆mexB, ∆mexF, and ∆mexB∆mexF, and investigated their sensitivity to plant-derived antimicrobial compounds, antibiotics, and virulence. Growth inhibition assays with KB soft agar plate showed that growth of the wild-type (WT) was inhibited by 5 μl of 1 M... -
Mode of Action of Streptomycin Resistance in the Citrus Canker Pathogen (Xanthomonas smithii subsp. citri) in Jeju Island
한국식물병리학회 The Plant Pathology Journal 5 Pages
한국식물병리학회 The Plant Pathology Journal 2012, 28권 2호 11 207-211 (5 pages)
It has been known that streptomycin resistance in bacteria can occur as a results of chromosomal mutation or through gene acquisition or both. Chromosomal mutations for resistances are point mutations in the rpsL gene, which alter ribosomal protein S12. Acquired resistance has occurred when an SmR plasmid carrying transposon Tn5393 with tandem strA-strB gene is transferred by conjugation. A total of 686 isolates of Xanthomonas smithii subsp. citri causal agent of citrus canker disease were... -
Molecular Mechanisms of Succinate Dehydrogenase Inhibitor Resistance in Phytopathogenic Fungi
Hyunkyu Sang, Hyang Burm Lee 한국식물병리학회 식물병연구 7 Pages
한국식물병리학회 식물병연구 2020, 26권 1호 1 1-7 (7 pages)
standing the molecular mechanisms of fungicide resistance is important for effective prevention and resis- tance management strategies. Two different mechanisms have currently been known in SDHI resistance. The SDHI target genes, SdhB, SdhC, and SdhD, mutation(s) confer resistance to SDHIs. In addition, overexpression of ABC transporters is involved in reduced sensitivity to SDHI fungicides. In this review, the current status of SDHI resistance mechanisms in phytopathogenic fungi is discussed. -
Src Family Kinase Inhibitor PP2 Induces LC3 Conversion in a Manner That is Uncoupled from Autophagy and Increases Apoptosis in Multidrug-Resistant Cells
Kim. Yun-Ki, Ahn. Jun-Ho, Lee. Mi-Chael 한국응용약물학회 Biomolecules & therapeutics 6 Pages
한국응용약물학회 Biomolecules & therapeutics 2012, Vol.20 No.4 393-398 (6 pages)
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Frequency of Antibiotic Resistance in Helicobacter pylori Strains Isolated from the Northern Population of Iran
Abadi. Amin Talebi Bezmin, Taghvaei. Tarang, Mobarez. Ashraf Mohabbati, Carpenter. Beth M., Merrell. D. Scott 한국미생물학회 The journal of microbiology 7 Pages
한국미생물학회 The journal of microbiology 2011, Vol.49 No.6 987-993 (7 pages)
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Gene Cloning and Characterization of MdeA, a Novel Multidrug Efflux Pump in Streptococcus mutans
Kim. Do Kyun, Kim. Kyoung Hoon, Cho. Eun Ji, Joo. Seoung-Je, Chung. Jung-Min, Son. Byoung Yil, Yum. Jong Hwa, Kim. Young-Man, Kwon. Hyun 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2013, Vol.23 No.3 430-435 (6 pages)
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Investigation of ${eta}$-Lactamase-producing Multidrug-resistant Pseudomonas aeruginosa Isolated from Non-Tertiary Care Hospitals in Korea
Sohn. Eui-Suk, Yoo. Jeong-Sik, Lee. Jeom-Kyu, Lee. Kyeong-Min, Chung. Gyung-Tae, Shin. Eun-Shim, Han. Sun-Young, Lee. Sang-Hee, Kim. Joo 한국미생물생명공학회 Journal of microbiology and biotechnology 5 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2007, Vol.17 No.10 1733-1737 (5 pages)
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Role of Integrin-Linked Kinase in Multi-drug Resistance of Human Gastric Carcinoma SGC7901/DDP Cells
Song. Wei, Jiang. Rui, Zhao. Chun-Ming 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 7 Pages
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP 2012, Vol.13 No.11 5619-5625 (7 pages)
