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561.

The Current Concept on Mechanism of Positive Inotropic Action of Cardiac Glycosides on the Heart

Lee Kwang-Soo 대한약리학회 대한약리학잡지 23 Pages

대한약리학회 대한약리학잡지 1986, 제 22권 제 1호 1 1-23 (23 pages)

Lee Kwang-Soo 저
...
- 5,200원
562.

백서의 뇌내 Opiate 수용체의 일중 변동에 미치는 Phenobarbital의 영향

박영걸(Yeoung-Gul Park), 김기원(Kee-Won Kim), 조규박(Kyu-Park Cho) 대한약리학회 대한약리학잡지 14 Pages

대한약리학회 대한약리학잡지 1985, 제 21권 제 2호 6 128-141 (14 pages)

박영걸(Yeoung-Gul Park), 김기원(Kee-Won Kim), 조규박(Kyu-Park Cho) 저
...
- 4,300원
실험적으로 명암에 적응시킨 백서의 뇌내 specific opiate binding과 β-endorphin 함량 일중변동에 미치는 지속적인 암적응, phenobarbital 장기처리의 영향을 관찰하고 opiate recptor binding과 β-endorphin 함량 양자간의 관계를 추구하여 다음과 같은 성적을 얻었다. 1. L : D, 12 : 12 주기에 적응시킨 대조군에서 maximum (3H)-morphine binding과 뇌내 β-endorphin 함량은 각각 22시 및 06시에 최고에 달하는 매우 특이한 일중변동을 보였고 24시간 평균 (3H)-morphine binding 및 뇌내 β-endorphin 함량은 각각 0.45+0.03...
563.

Fe++및 H2O2에 의한 hyaluronic acid 분해에 있어서 ascorbic acid의 역할

이정수(Jung-Soo Lee), 정명희(Myung-Hee Chung), 임정규(Jung-Kyoo Lim), 박찬웅(Chan-Woong Park), 차인준(In-Joon Cha) 대한약리학회 대한약리학잡지 17 Pages

대한약리학회 대한약리학잡지 1985, 제 21권 제 1호 6 62-78 (17 pages)

이정수(Jung-Soo Lee), 정명희(Myung-Hee Chung), 임정규(Jung-Kyoo Lim), 박찬웅(Chan-Woong Park), 차인준(In-Joon Cha) 저
...
- 4,600원
Hydroxyl raical(OH⋅)을 생성하는 것으로 알려진 iron-catalyzed Haber-Weiss rocation에서 superoxide anion (O2-⋅)은 주로 Fe+++을 Fe++로 환원시키는 데에 작용하는 것으로 추정하고 있다. 이러한 OH⋅ 의 역할은 다른 환원제들에 의하여 대체가 가능할 것으로 추측되며 생물계의 환원제의 하나로써 ascorbate가 관심의 대상이 되고 있다. 이에 따라 본 연구에서는 Fe++와 H2O2 존재하에서 OH⋅ 을 생성하는 ascorbate 의 역할을 hyaluronic acid의 변성과 methional로 부터 ethylene 생성에 대한 효과로써...
564.

Effect of Cadmium on Organic Acid Transport System in Renal Basolateral Membrane

Kim, Ghi-Chan, Kim, Kyoung-Ryong, Kim, Jee-Yeun, Park, Yang-Saeng 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 10 279-288 (10 pages)

Kim, Ghi-Chan, Kim, Kyoung-Ryong, Kim, Jee-Yeun, Park, Yang-Saeng 저
...
- 3,000원
in Na+ and αKG-independent transport component. Kinetic analysis indicated that Vmax, but not Km, of the Na+-dependent, αKG-driven component was reduced. A similar reduction of Na+-dependent, αKG-driven PAH uptake was observed in normal membrane vesicles directly exposed to inorganic cadmium in vitro, and this was accompanied by an inhibition of both Na+-dependent αKG uptake and αKG-PAH exchange activity. These results indicate that during chronic exposure to cadmium, free cadmium ions...
565.

Endothelium-dependent Contraction of Aorta in One-kidney, One-clip Goldblatt Hypertensive Rat

Jeon, Byeong-Hwa, Lee, Kug-Hee, Kim, Hoe-Suk, Kim, Se-Hoon, Chang, Seok-Jong 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 9 269-278 (10 pages)

Jeon, Byeong-Hwa, Lee, Kug-Hee, Kim, Hoe-Suk, Kim, Se-Hoon, Chang, Seok-Jong 저
...
- 3,000원
The mechanism of impaired endothelium-dependent relaxation in the aorta of one-kidney, one clip Goldblatt hypertensive (1K,1C-GBH) rats was investigated. 8 week-old Wistar-Kyoto (WKY) rats were made hypertensive by left renal artery stenosis with contralateral nephrectomy. Endothelium-dependent relaxation was significantly reduced in 1K,1C-GBH rats as compared with WKY rats. However, the relaxation by sodium nitroprusside in 1K,1C-GBH rats was not reduced as compared with WKY rats. The...
566.

Effects of High Glucose Levels on the Protein Kinase C Signal Transduction Pathway in Primary Cultured Renal Proximal Tubule Cells

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 대한생리학회 대한생리학회지 12 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 8 257-268 (12 pages)

Han, Ho-Jae, Kang, Ju-Won, Park, Kwon-Moo 저
...
- 4,100원
Diabetes mellitus is associated with a wide range of pathophysiologic changes in the kidney. This study was designed to examine the mechanisms by which glucose modulates the expression of polarized membrane transport functions in primary cultured rabbit renal proximal tubule cells. Results are as follows: The rate of 30 minute Rb+ uptake was significantly higher(137.76±5.40%) in primary renal tubular cell cultures treated with 20 mM glucose than that of 5 mM glucose. Not the level of mRNA for...
567.

Effect of Probenecid on Tetraethylammonium (TEA) Transport Across Basolateral Membrane of Rabbit Proximal Tubule

Choi, Tae-Ryong, Kim, Yong-Keun, 대한생리학회 대한생리학회지 8 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 2호 7 249-256 (8 pages)

Choi, Tae-Ryong, Kim, Yong-Keun, 저
...
- 3,000원
mM probenecid. Kinetic analysis indicated that probenecid decreased Vmax without significant change in Km. Probenecid inhibited significantly tissue oxygen consumption at concentrations of 3 and 5 mM. However, probenecid did not significantly reduce TEA uptake in brush border and basolateral membrane vesicles prepared from renal cortex even at a concentration as high as 10 mM. These results indicate that probenecid reduces TEA uptake in cortical slices by inhibiting tissue metabolism rather than...
568.

Effects of Insulin and IGFs on Phosphate Uptake in Primary Cultured Rabbit Renal Proximal Tubule Cells

Han, Ho-Jae, Park, Kwon-Moo 대한생리학회 대한생리학회지 14 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 7 63-76 (14 pages)

Han, Ho-Jae, Park, Kwon-Moo 저
...
- 4,300원
The aim of present study was to characterize phosphate uptake and to investigate the mechanism for the insulin and insulin-like growth factor(IGF) stimulation of phosphate uptake in primary cultured rabbit renal proximal tubule cells. Results were as follows : 1. The primary cultured proximal tubule cells had accumulated 6.68±0.70 nmole phosphate/mg protein in the presence of 140 mM NaCl and 2.07±0.17 nmole phosphate/mg protein in the presence of 140 mM KCl during a 60 minute uptake period....
569.

Transepithelial Transport of Organic Cation and Its Inhibition by Sulfhydryl and Carboxyl Reagents in Opossum Kidney Cell Monolayer

Woo, Jae-Suk, Oh, Se-Ok, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 6 53-62 (10 pages)

Woo, Jae-Suk, Oh, Se-Ok, Jung, Jin-Sup, Kim, Yong-Keun, Lee, Sang-Ho 저
...
- 3,000원
Transepithelial transport of tetraethylammonium (TEA) was studied in monolayers of opossum kidney cells cultured on permeable membrane filters. [14C]-TEA was transported across the OK cell monolayer from basolateral to apical side by a saturable process which can be stimulated by acidification of the apical medium. The apparent Michaelis-Menten constant (Km) and the maximum velocity(Vmax) for the transport were 41 μM and 147 pmole/ mg protein/ min, respectively. The transport was significantly...
570.

Effects of Adenosine on the Ionic Channel Activated by Metabolic Inhibition in Rabbit Ventricular Myocytes

Han, Jin, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 대한생리학회 대한생리학회지 10 Pages

대한생리학회 대한생리학회지 1996, 제 30권 제 1호 1 1-10 (10 pages)

Han, Jin, Kim, Eui-Yong, Ho, Won-Kyung, Earm, Yung-E 저
...
- 3,000원
The objective of the present study was to characterize the role of adenosine in regulation of ATP-sensitive K+ channel (KATP channel) activity in isolated rabbit ventricular myocytes using the patch clamp technique. Internal adenosine had little effects on KaTr channel activity. In an outside-out patch with intrapipette GTP and ATP, external adenosine stimulated KATP channel activity. In an inside-out Patch with intrapipette adenosine, ATP reduced KATP channel activity, and GTP stimulated KATP...

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