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Role of Stretch-Activated Channels in Stretch-Induced Changes of Electrical Activity
JaeBoumYoum, Su-HyunJo, ChaeHunLeem, Won-KyungHo, YungE. 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.1 6 33-41 (9 pages)
mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels, pumps, exchangers, and changes of intracellular ion concentration. Changes in membrane excitability and Ca2 transients could then be calculated. In the model, the major ion channels responsible for the stretch-induced changes in electrical activity were the stretch-activated channels (SACs). The relationship between the extent of stretch and activation of... -
Normal Anxiety, Fear and Depression-related Behaviors in Mice Lacking α-Calcitonin Gene-Related Peptide
JonghoLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2002, Vol.6 No.6 4 299-304 (6 pages)
Calcitonin gene-related peptide (CGRP) expressing neurons are distributed widely throughout the central and peripheral nervous systems. Due to its distribution and pharmacological studies, CGRP has been implicated to be involved in anxiety, fear and depression. In this study, αCGRP-knockout mice were used to assess the consequences of removing this neuropeptide to the mice behaviors. αCGRP-knockout mice performed equally as well as wild type mice in the light-dark transition test and in the... -
Nitroxergic Nerve Relaxes Rat Gastric Smooth Muscle by NO-cGMP Pathway
YoongSamYoon, HyoungChulChoi, YoungSookJung, JongHoKim, KwangYounLee, UyDongSohn, JeoungHeeHa, WonJoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.5 5 369-378 (10 pages)
induced by electric field stimulation (EFS). Pretreatment of NG-nitro-L-arginine methyl ester (L-NAME), a NOS inhibitor, increased the EFS-induced contractions. LY 83583, a guanylate cyclase (GC) inhibitor, reversed the inhibitory actions of L-arginine on the muscle contractions. The effects of L-Arginine, L-NAME and LY 83583 on ACh-induced contractions were not significant. L-arginine reduced the EFS-induced contraction in circular muscle, whereas L-NAME enhanced the EFS-induced contraction in... -
Relatoinship between Sarcoplasmic Reticular Calcium Release and Na+-Ca2+ Exchange in the Rat Myocardial Contraction
Eun-GiKim, SoonJinKim, ChangMannKo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 14 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.3 4 197-210 (14 pages)
Suppressive role of Na-Ca2 exchange in myocardial tension generation was examined in the negative frequency-force relationship (FFR) of electric field stimulated left atria (LA) from postnatal developing rat heart and in the whole-cell clamped adult rat ventricular myocytes with high concentration of intracellular Ca2 buffer (14 mM EGTA). LA twitch amplitudes, which were suppressed by cyclopiazonic acid in a postnatal age-dependent manner, elicited frequency-dependent and... -
Hemorrhage- and Restraint-induced Analgesia in Male and Female Conscious Rats
SungYunOh, HeeSeokHan, DongKukAhn, JaeSikPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.6 3 555-563 (9 pages)
It is well known that stress induces analgesia. This study was designed to demonstrate the stress-induced analgesia by employing hemorrhage and restraint and to investigate its mechanism and sex difference. The degree of pain was assessed by measuring the magnitude of jaw opening reflex produced by a noxious electrical stimulation in the dental pulp and by measuring the latency to withdraw the tail from a heat ray. Restraint showed an antinociceptive response. A significant increase in pain... -
The Role of Somatostatin in Nociceptive Processing of the Spinal Cord in Anesthetized Cats
SungJunJung, JooMinPark, JunHoLee, JihyeLee, SangJeongKim, JunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.4 1 365-373 (9 pages)
to the receptive field. Sciatic nerve was stimulated electrically to evoke Aδ- and C-nociceptive responses. SOM analogue, octreotide (10 μg/kg), was applied intravenously and the results were compared with those of morphine (2 mg/kg, MOR). Systemic SOM decreased the cellular responses to the noxious heat and the mechanical stimulation, but increased those to the cold stimulation. In the responses to the electric stimuli of sciatic nerve, Aδ-nociceptive response was increased by SOM, while... -
흡연이 청각사건관련전위 P300에 미치는 영향
전창만, 김병광, 이창욱, 한상익, 백인호 대한신경정신의학회 신경정신의학 7 Pages
대한신경정신의학회 신경정신의학 1997, 제 36권 제 6호 14 1099-1105 (7 pages)
흡연이 중추신경계에 미치는 영향을 알아보기 위하여 흡연자 24명과 비흡연자 14명을 대상으로 흡연 전 후에 지표학적 전산화 청각 사건관련전위 검사를 시행하고 이를 아직까지 흡연연구에 시도된바 없는 전부위 장력 측정법으로 잠복기를 분석하여 다음과 같은 결과를 얻었다. 1) 흡연군과 비흡연군사이에서 P300의 잠복기를 비교하였을 때, 흡연군에서 흡연전값이 324.0±30.1 흡 연후 값이 309.8±31.5였고 비흡연군에서 흡연전값이 329.6±49.6 흡연후 값이 344±48.3으로 흡연군에 서 비흡연군에 비해 흡연 후에 잠복기가 유의하게... -
주의력결핍 과잉행동장애 아동의 주의집중력의 특성: 시각 및 청각 TOVA와 지능검사 결과를 중심으로
최보문, 이방락 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 5호 7 870-878 (9 pages)
연구목적: 주의집중력의 장애를 주 호소로 내원한 임상 아동들 중에서 주의력 결핍 과잉행동 장애로 진단된 아동과 기타 임상집단 아동의 주의집중력이 지능지수와 시각및 청각 TOVA에서 어떻게 나타나는지 알아보고자 본 연구를 시도하였다. 방 법: 주의집중력의 장애를 주 호소로 내원한 47명의 환아중, 주의력결핍 과잉행동 장애로 진단된 24명의 아동 과 그 외의 질환으로 진단된 23명의 아동을 대상으로 하였다. 두 대상 집단의 지능검사를 변인으로 하여 시 각및 청각 TOVA의 결과를 비교하였다. 결 과: ADHD 집단의 아동은... -
흰쥐의 중추성 Serotonin 고갈이 강제수영 중 부동자세 시간,불안 및 수동적 회피 학습에 미치는 효과
박제민, 김종백, 강철중 대한신경정신의학회 신경정신의학 11 Pages
대한신경정신의학회 신경정신의학 1996, 제 35권 제 3호 19 699-709 (11 pages)


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