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Peptide Transporter Substrate Identification during Permeability Screening in Drug Discovery: Comparison of Transfected MDCK-hPepT1 Cells to Caco-2 Cells
Chong. Sae-Ho, Patel. Karishma, Quan. Yong, Timoszyk. Julita, Han. Yong-Hae, Wang. Bonnie, Vig. Balvinder, Faria. Teresa N., Balimane. P 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 12 Pages
대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 2007, Vol.30 No.4 507-518 (12 pages)
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Induction of insulin receptor substrate-2 expression by Fc fusion to exendin-4 overexpressed in E. coli: a potential long-acting glucagon-like peptide-1 mimetic
Kim. Jae-Woo, Kim. Kyu-Tae, Ahn. You-Jin, Jeong. Hee-Jeong, Jeong. Hyeong-Yong, Ryu. Seung-Hyup, Lee. Seung-Yeon, Lee. Chang-Woo, Chung. 생화학분자생물학회 BMB reports 4 Pages
생화학분자생물학회 BMB reports 2010, Vol.43 No.2 146-149 (4 pages)
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Analysis of protein expression in Brucella abortus mutants with different growth rates by two-dimensional gel electrophoresis and LC-MS/MS peptide analysis
Woo Bin Park, Young Bin Im, Soojin Shim, Han Sang Yoo 대한수의학회 Journal of Veterinary Science 16 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 8 216-231 (16 pages)
those with a change of more than 2-fold were compared with the wild-type. Selected spots underwent liquid chromatography tandem mass spectrometry for peptide analysis. DnaK and ClpB, involved in protein aggregation, increased. SecA and GAPDH, associated with energy metabolism, decreased in some mutants with a growth rate slower than that of the wild-type. Mutants with slower growth showed a decrease in energy metabolism-related proteins, while mutants with faster growth showed an increase in... -
Calcium-sensing receptor-mediated L-tryptophan-induced secretion of cholecystokinin and glucose-dependent insulinotropic peptide in swine duodenum
Xiuying Zhao, Yihan Xian, Chao Wang, Liren Ding, Xianglong Meng, Weiyun Zhu, Suqin Hang 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2018, 제 19권 제 2호 4 179-187 (9 pages)
cholecystokinin (CCK) and glucose-dependent insulinotropic peptide (GIP), elevated the mRNA level of CaSR, and upregulated the protein levels of CaSR, protein kinase C (PKC), and inositol trisphosphate receptor (IP3R). However, NPS 2143, an inhibitor of CaSR, attenuated the CCK and GIP release, reduced the mRNA level of CaSR, and decreased the protein levels of CaSR, PKC, and IP3R with 20 mM Trp perfusion. The results indicate that CCK and GIP secretion can be induced by Trp in swine duodenum in... -
Development of synthetic peptide ELISA based on nonstructural protein 2C of foot and mouth disease virus
Jae Ku Oem, Soo Jeong Kye, Kwang Nyeong Lee, Jong Hyeon Park, Yong Joo Kim, Hee Jong Song, Max Yeh 대한수의학회 Journal of Veterinary Science 9 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 4호 10 317-325 (9 pages)
and five goats infected with FMDV O/SKR/2000 experimentally, positive results were obtained in two species after 10 days post infection (DPI). Therefore, we tried to develop and evaluate this ELISA based on 2C peptides. In comparison with the commercial NSP ELISA, the 2C peptide based ELISA method showed good specificity and sensitivity. These results demonstrate that the synthetic 2C peptide ELISA can be a complementary marker to differentiate FMDV-infected from vaccinated on a herd basis. -
Inhibition of β-amyloid1-40 Peptide Aggregation and Neurotoxicity by Citrate
YongHoonPark, Young-JinKim, IlHongSon, HyunDukYang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.4 2 273-279 (7 pages)
The accumulation of Ղ-amyloid (AՂ) aggregates is a characteristic of Alzheimer's disease (AD). Furthermore, these aggregates have neurotoxic effects on cells, and thus, molecules that inhibit AՂ aggregate formation could be valuable therapeutics for AD. It is well known that aggregation of AՂ depends on its hydrophobicity, and thus, in order to increase the hydrophilicity of AՂ, we considered using citrate, an anionic surfactant with three carboxylic acid groups. We... -
Effect of Atrial Natriuretic Peptide on the Proliferation and Activity of Osteoblastic Cells
Jong-RyeulLee, Seon-YleKo, Jung-KeunKim, Se-WonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2000, Vol.4 No.4 3 283-289 (7 pages)
three structurally related peptides; atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The present study was performed to investigate the effect of ANP on the proliferation and activity of ROS17/2.8 and HOS cells which are well-characterized osteoblastic cell lines. ANP dose-dependently decreased the number of ROS17/2.8 and HOS cells after 48-hour treatment. ANP generally increased the alkaline phosphatase activity of ROS17/2.8 and HOS cells... -
자라 신장기능에 미치는 Atrial Natriuretic Peptide의 효과
조경우(Cho, Kyung-Woo), 김선희(Kim, Suhn-Hee), 고규영(Koh, Gou-Young), 설경환(Seul, Kyung-Hwan) 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1987, 제 21권 제 1호 2 13-22 (10 pages)
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Preparation of gold nanoparticle/single-walled carbon nanotube nanohybrids using biologically programmed peptide for application of flexible transparent conducting films
MinHo Yang, Bong Gill Choi 한국탄소학회 Carbon Letters 6 Pages
한국탄소학회 Carbon Letters 2016, Vol.20 4 26-31 (6 pages)
In this study, we report a general method for preparation of a one-dimensional (1D) arrangement of Au nanoparticles on single-walled carbon nanotubes (SWNTs) using biologically programmed peptides as structure-guiding 1D templates. The peptides were designed by the combination of glutamic acid (E), glycine (G), and phenylalanine (F) amino acids; peptides efficiently debundled and exfoliated the SWNTs for stability of the dispersion and guided the growth of the array of Au nanoparticles in a... -
A Putative Peptide Synthetase from Bacillus subtilis 713 Recognizing $_{L}-Lysine,{;}_{L}-Tryptophan,{;}and{;}_{L}-Glutamic$ Acid
Kim. Kyoung-Rok, Lee. In-Hyung, Suh. Joo-Won 한국미생물생명공학회 Journal of microbiology and biotechnology 6 Pages
한국미생물생명공학회 Journal of microbiology and biotechnology 2001, Vol.11 No.5 798-803 (6 pages)


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