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Effect of Stimulus Waveform of Biphasic Current Pulse on Retinal Ganglion Cell Responses in Retinal Degeneration (rd1) mice
KunNoAhn, JeongYeolAhn, Jae-hyungKim, KyoungrokCho, Kyo-inKoo, SolomonS.Senok, YongSookGoo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 12 167-175 (9 pages)
of vision in patients with retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Determining optimal electrical stimulation parameters for the prosthesis is one of the most important elements for the development of a viable retinal prosthesis. Here, we investigated the effects of different charge-balanced biphasic pulses with regard to their effectiveness in evoking retinal ganglion cell (RGC) responses. Retinal degeneration (rd1) mice were used (n=17). From the ex-vivo retinal... -
Spontaneous Oscillatory Rhythm in Retinal Activities of Two Retinal Degeneration (rd1 and rd10) Mice
YongSookGoo, KunNoAhn, YeongJunSong, SuHeokAhn, SeungKeeHan, SangBaekRyu, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 13 415-422 (8 pages)
Previously, we reported that besides retinal ganglion cell (RGC) spike, there is ∼10 Hz oscillatory rhythmic activity in local field potential (LFP) in retinal degeneration model, rd1 mice. The more recently identified rd10 mice have a later onset and slower rate of photoreceptor degeneration than the rd1 mice, providing more therapeutic potential. In this study, before adapting rd10 mice as a new animal model for our electrical stimulation study, we investigated electrical characteristics of... -
Microarray Analysis of Differentially Expressed Genes in the Brains of Tubby Mice
JeongHoLee, ChulHoonKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 4 91-98 (8 pages)
The tubby mouse is characterized by progressive retinal and cochlear degeneration and late-onset obesity. These phenotypes are caused by a loss-of-function mutation in the tub gene and are shared with several human syndromes, suggesting the importance of tubby protein in central nervous system (CNS) functioning. Although evidence suggests that tubby may act as a transcription factor mediating G-protein coupled receptor (GPCR) signaling, any downstream gene regulated by tubby has yet to be... -
교장직의 전문성 제고를 위한 정책방향
주삼환 한국교원교육학회 한국교원교육학회 학술대회자료집 25 Pages
한국교원교육학회 한국교원교육학회 학술대회자료집 교원정책포럼 2 20-44 (25 pages)
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저전력 아날로그 CMOS 윤곽검출 시각칩의 설계
김정환, 박종호, 서성호, 이민호, 신장규, 남기홍, Kim. Jung-Hwan, Park. Jong-Ho, Suh. Sung-Ho, Lee. Min-Ho, Shin. Jang-Kyoo, Nam. Ki-Hong 한국센서학회 센서학회지 10 Pages
한국센서학회 센서학회지 2003, Vol.12 No.6 231-240 (10 pages)
고해상도의 윤곽검출 시각칩을 제작하기 위해 윤곽검출 회로의 수를 증가시킬 경우 소비전력 문제 및 회로를 탑재할 칩의 크기를 고려하지 않으면 안된다. 칩을 구성하는 단위회로의 수적 증가는 소비전력의 증가와 더불어 대면적을 요구하게 된다. 소비전력의 증가와 CMOS 생산 회사에서 제공하는 칩의 크기가 수 십 $mm^2$이라는 조건은 결국 단위회로의 수적 증가를 제한하게 된다. 따라서 본 연구에서는, 고해상도의 윤곽검출 시각칩 구현을 위한 윤곽검출 회고의 수적 증가에 따른 전력소비의 최소화 방법으로 전자스위치(electronic...
