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사춘기 암컷 랫드에서 갑상선 시험에 의한 Methoxychlor의 에스트로젠 효과
정문구, 김종춘, 임광현 한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 5 Pages
한국독성학회 Journal of toxicology and public health : an official journal of the Korean Society of Toxicology 2000, Vol.16 No.1 27-31 (5 pages)
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Methoxychlor투여 흰쥐에 있어서 복분자 술이 Testosterone에 미치는 효과
이성일, 황인수, 허진, 임채웅, 주성민, 전병훈, 백병걸, Lee. Sung-Il, Whang. In-Soo, Hur. Jin, Lim. Chae-Woong, Ju. Sung-Min, Jeon. Byung-Hun, Baek. Byeong-Kirl 대한동의생리학회 동의생리병리학회지 6 Pages
대한동의생리학회 동의생리병리학회지 2005, Vol.19 No.3 656-661 (6 pages)
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Methoxychlor 투여한 흰쥐에 있어서의 Testosterone의 변화
백병걸, 이부웅, 임채웅, 권혁년, 허진, 이은영, 이희권, 이성일, 김병수, 이형자, 전병훈, Baek. Byeong Kirl, Lee. Bou Oung, Lim. Chae Woong, Kwon. Hyuk Nyun, Hur. Jin, Lee. Eun Yon 대한동의생리학회 동의생리병리학회지 6 Pages
대한동의생리학회 동의생리병리학회지 2004, Vol.18 No.4 1163-1168 (6 pages)
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Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen
Yoot Mo Lee, Min Jae Seong, Jae Woong Lee, Yong Kyung Lee, Tae Myoung Kim, Sang-Yoon Nam, Dae Joong Kim, Young Won Yun, Tae Seon 대한수의학회 Journal of Veterinary Science 12 Pages
대한수의학회 Journal of Veterinary Science 2007, 제 8권 제 1호 5 27-38 (12 pages)
health. Some examples of this diverse group of compounds include industrial chemicals (e.g., bisphenol A, alkyl phenols, phthalates, polychlorinated biphenyls) and pesticides (e.g., DDT, methoxychlor, dieldrin, toxaphene, endosulfan). These estrogen-like chemicals are becoming ubiquitous in the environment, and humans are being exposed to these chemicals through the food chain [11]. Bisphenol A... Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological activity through estrogen receptor (ER) -α and -β, which are expressed in the central nervous system. We previously found that exposure of BPA to immature mice resulted in behavioral alternation, suggesting that overexposure of BPA could be neurotoxic. In this study, we further investigated the molecular neurotoxic mechanisms of BPA. BPA... -
Requirement of Metabolic Activation for Estrogenic Activity of Pueraria mirifica
Y.S. Lee, J.S. Park, S.D. Cho, J.K. Son, W. Cherdshewasart and K.S. Kang 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 4호 4 273-277 (5 pages)
al.[18] showed that methoxychlor (proestrogen) was inactive in the yeast assay system,whereas HPTE was active.This suggests that yeast assay system lack the ability to demethylate methoxychlor and may miss certain proestrogens, leading to negative results. HepG2 cell based system is apparently less sensitive to the action of 17β-estradiol compared to the yeast system but this system has the known... A wide range of chemicals derived from plant and human-made xenobiotics are reported to have hormonal activities. The present study was performed to examine the estrogenic effect of Kwao Keur, Pueraria mirifica (PM), that has been used as a rejuvenating folk medicine in Thailand, using recombinant yeast, MCF-7 cell proliferation and HepG2 cell transient transfection assay. In recombinant yeast assay, 0.025, 0.25, 2.5, 25, 2.5 x 10(2), 2.5 x 10(3), 2.5 x 10(4) ng/ml concentrations of PM did not... -
원저 : 랫드에서 amitraz의 출생 전후 발생 시험
김성환, 임정현, 박나형, 문창종, 박수현, 강성수, 배춘식, 김성호, 신동호, 김종춘 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 11 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2010, 제 50권 제 2호 3 93-103 (11 pages)
diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice. Horm Behav 2001, 40, 252-265. 27. Palermo-Neto J, Flrio JC, Sakate M. Developmental and behavioral effects of prenatal amitraz exposure in rats. Neurotoxicol Teratol 1994, 16, 65-70. 28. Palermo-Neto J, SkatM, Flrio JC. Developmental and behavioral effects of postnatal amitraz... -
실험동물에서의 환경호르몬 물질의 생체내 영향 및 검색법 정립에 대한 연구
정지윤, 이영순 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2005, 제 45권 제 4호 13 545-552 (8 pages)
of di-(2-ethylhexyl) phthalate from urine of laboratory animals. J Chromotogr 1982, 244, 65-79. 2. Bulger WH, Nuccitelli RM, Kupfer D. Studies on the in vivo and vitro estrogenic activities of methoxychlor and its metabolites role of hepatic mono-oxygenase in methoxychlor activation. Biochem Pharmacol 1978, 27, 2417-2423. 3. Harris CA, Henttu P, Parker MG, Sumpter JP. The Estrogenic activity of...