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Feasibility of utilizing the patellar ligament angle for assessing cranial cruciate ligament rupture in dogs
Jung-ha Lee, Soon-wuk Jeong 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 4호 8 563-568 (6 pages)
The patellar ligament angle (PLA) was assessed in 105 normal stifle joints of 79 dogs and 33 stifle joints of 26 dogs with a ruptured cranial cruciate ligament (CrCL). The PLA of stifles with complete CrCL rupture was significantly lower than that of normal stifles, particularly at a flexion angle of 60∼80o in both plain and stress views. If the PLA was ＜90.55o on the stress view with a 60∼80o flexion angle, the dog was diagnosed with a complete rupture of the CrCL with a sensitivity of 83.9%... -
Use of a domestic Korean black goat (Capra hircus coreanae) with its chest crayon-harnessed in detecting estrus of Himalayan tahrs (Hemitragus jemlahicus)
Hwanyul Yong, Eunsong Lee* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 3호 12 427-432 (6 pages)
(Capra hircus coreanae) to detect estrus in Himalayan tahrs (Hemitragus jemlahicus) for an artificial breeding program was investigated. Estrus in six female Himalayan tahrs was synchronized using fluorogestone acetate (FGA) sponges. Thirteen days later, 200 IU of PMSG and 100 IU of hCG were injected before removing the sponges and simultaneously injecting 5 mg of PGF2α the next day. Penetration of the cervical canal and the thickness and location of red crayon marks were examined 40∼43 h late... -
Evaluation of bone healing in canine tibial defects filled with cortical autograft, commercial-DBM, calf fetal DBM, omentum and omentum-calf fetal DBM
Amin Bigham-Sadegh, Iraj Karimi, Mahsa Alebouye, Zahra Shafie-Sarvestani, Ahmad Oryan 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 3호 14 337-343 (7 pages)
in the other group (p ＜ 0.05). On the 28th postoperative day, the autograft group was significantly superior to the control and omentum groups (p ＜ 0.05). Moreover, calf fetal DBM was significantly superior to the control group. There was no significant difference between the histopathological sections of all groups. Overall, the omentum and omentum-DBM groups were superior to the control group, but inferior to the autograft, commercial-DBM, calf fetal DBM and calf fetal cartilage groups. -
Comparison of bare metal stent and paclitaxel-eluting stent using a novel rat aorta stent model
Jin Sook Kwon, Rho Kwan Park, Tae Jin Shim, Myung Ho Jeong, Myeong Chan Cho, Youngkeun Ahn, Dong-Woon Kim 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 2호 6 143-150 (8 pages)
novel rat aorta stent implantation model. Stainless steel bare metal stents (BMS) or paclitaxel-eluting stents (PES) were implanted in male Sprague-Dawley rats (BW 400 ± 20 g). Two and four weeks after stent implantation, the aorta were collected, fixed with 2% glutaraldehyde, and cut into two segments. One segment was used for scanning electron microscopy analysis to evaluate re-endothelialization, and the other segment was used to calculate the neointimal area. At 2 weeks after stenting, the... -
Human embryonic stem cells and therapeutic cloning
Woo Suk Hwang, Byeong Chun Lee, Chang Kyu Lee, Sung Keun Kang 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2005, 제 6권 제 2호 1 87-96 (10 pages)
The remarkable potential of embryonic stem (ES) cells is their ability to develop into many different cell types. ES cells make it possible to treat patients by transplanting specialized healthy cells derived from them to repair damaged and diseased cells or tissues, known as “stem cell therapy”. However, the issue of immunocompatibility is one of considerable significance in ES cell transplantation. One approach to overcome transplant rejection of human ES (hES) cells is to derive hES cells... -
Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth
Dong Ho Bak, Mi Ji Choi, Soon Re Kim, Byung Chul Lee, Jae Min Kim, Eun Su Jeon, Wonil Oh, Ee Seok Lim, Byung Cheol Park, Moo Joong Kim, Ju 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2018, Vol.22 No.5 9 555-566 (12 pages)
Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of hUCB-MSCs treatment to determine whether hUCB-MSCs enhance the promotion of hair growth. Furthermore, we attempted to identify the factors responsible for hair growth. The effects of hUCB-MSCs on hair growth were investigated in vivo, and hUCB-MSCs advanced anagen onset and hair... -
Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats
YanLan, Huan-JunLu, XianJiang, Li-WeiLi, Yan-ZhaoYang, Guang-ShiJin, JooYoungPark, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2015, Vol.19 No.2 11 159-165 (7 pages)
of glutamate release was significantly increased in the RVLM in control, BL, SAD groups following SNP infusion, and this peaked 10 min after SNP infusion. The SAD group showed a relatively higher reduction in glutamate release when compared with the BL group. These results suggest that the baroreceptors are more powerful in pERK expression and glutamate release in the RVLM following hypotension than the vestibular receptors, but the vestibular receptors still have an important role in the RVLM. -
Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats
SeungwooKim, Joong-KeunShin, HyungShinYoon, Jeong-HoonKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 10 389-396 (8 pages)
Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such effects of these drugs. Although the nucleus accumbens (NAcc) is the site mediating the expression of behavioral sensitization by drugs of abuse, the precise role of ERK activation in this site has not been determined. In this study we demonstrate that... -
The Effects of Tramadol on Electroencephalographic Spectral Parameters and Analgesia in Rats
Hwan-SooJang, Il-SungJang, Maan-GeeLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.3 12 191-198 (8 pages)
The effects of different doses of tramadol on analgesia and electroencephalographic (EEG) spectral parameters were compared in rats. Saline or tramadol 5, 10, 20 or 40 mg/kg was administered. The degree of analgesia was evaluated by tail-flick latency, and the degree of seizure was measured using numerical seizure score (NSS). Additionally, band powers, median power frequency and spectral edge frequency 95 were measured to quantify the EEG response. All doses of tramadol produced spike-wave... -
Electrically-evoked Neural Activities of rd1 Mice Retinal Ganglion Cells by Repetitive Pulse Stimulation
SangBaekRyu, JangHeeYe, JongSeungLee, YongSookGoo, ChiHyunKim, KyungHwanKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 6 443-448 (6 pages)
For successful visual perception by visual prosthesis using electrical stimulation, it is essential to develop an effective stimulation strategy based on understanding of retinal ganglion cell (RGC) responses to electrical stimulation. We studied RGC responses to repetitive electrical stimulation pulses to develop a stimulation strategy using stimulation pulse frequency modulation. Retinal patches of photoreceptor-degenerated retinas from rd1 mice were attached to a planar multi-electrode array... -
할로페리돌로 유도한 신경세포 고사에 대한 신경성장인자 및 인슐린 유사 성장인자의 억제효과
강효정, 강지윤, 곽병주, 정영기, 노재성 대한신경정신의학회 신경정신의학 8 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 5호 12 920-927 (8 pages)
연구목적： 본 연구는 생쥐 태자의 대뇌피질 세포 일차 배양을 이용하여 할로페리돌로 유도한 신경세포의 사멸에 대 해 신경 성장인자인 brain-dervied neurotrophic factor(BDNF), Neurotrophin 4/5(NT 4/5)와 인슐린 유 사 성장인자인 insulin-like growth factor Ⅰ(IGF-Ⅰ) 및 IGF-Ⅱ의 조절효과를 실험한 것이다. 방 법： 생쥐 태자의 신경세포를 배양한 후 할로페리돌을 처리하여 신경세포의 사멸을 유도하고 이에 대한 성장인 자의 효과를 정량적으로 분석하였다. 결 과： 30 M의 할로페리돌을 배양한 일차 대뇌 피질 신경세포에... -
실험적 고혈압 백서의 심맥관계 기능조절에 있어서 중추 Opiate System의 역할
김기원(Kee-Won Kim), 곽용근(Yong-Geun Kwak), 채준석(Joon-Seak Chae), 조규박(Kyu-Park Cho) 대한약리학회 대한약리학잡지 10 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 7 123-132 (10 pages)
Morphine을 비롯한 opioid peptide가 말초 또는 중추에 투여시 혈압하강과 심박동수감소를 보이며 opiate 수용체 길항제인 naloxone에 의해 길항됨이 관찰되었던바 근래 몇몇 보고들은 중추신경내에서 adrenergic및 opioidergic system이 서로 관련되어 있음을 시사하고 있다. 이에 본 실험에서 고혈압 연구에 널리 사용되고 있는 2-kidney, 1-clip (2K1C) 방법으로 실험적 고혈압을 유발시킨 백서의 측뇌실내 clonidine또는 morphine의 심맥관계에 대한 효과와 각각의 차단제에 의한 영향 그리고 정상 및 고혈압상태 백서의 뇌내... -
가토의 ouabain 유발 부정맥에 미치는 acebuolol 및 carbamazepine의 영향
김원준(Won Joon Kim), 하정희(Jeoung Hee Ha) 대한약리학회 대한약리학잡지 6 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 1호 2 9-14 (6 pages)
Adrenergic beta 1 수용체 봉쇄 약물인 acebutolol과 항 경련제로 사용되고 있는 carbamazepine은 실험적으로 ouabain유발 부정맥을 정상 심박동으로 환원시키는데 유효하다고 보고되었으나 그 상호 작용에 대해서는 밝혀진 바가 없다. 이에 본 실험에서는 가토에 ouabain 투여로 부정맥을 유발시킨 후 acebutolol과 carbamazepine을 단독 혹은 병용 투여하여 이 두 약물이 ouabain 유발 부정맥에 미치는 영향과 그 상호 작용을 규명하고자 하였다. 실험 결과 ouabain 유발 부정맥은 acebutolol 혹은 carbamazepine 단독 투여로 정상... -
Ventilatory Responses to Continuous Negative Pressure Breathing(CNPB) in Awake Dogs
Cha, Eun-Jong, Goo, Yong-Sook 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 4 37-50 (14 pages)
Ventilatory responses to inhaled CO2 were measured during continuous negative pressure breathing (CNPB) in awake dogs. End expiratory lung volume (EELV) decreased linearly with pressure level during CNPB (correlation coefficient= 0.81, p<0.005) during air breathing. When CNPB was applied during 5% CO2 inhalation, the decrease in EELV was not significantly different (p<0.5) from that during air breathing. As a result of a lowered EELV, tidal volume (VT) significantly decreased by 22% and... -
Effect of Changing Amniotic Fluid Osmolarity on the Li+ Transport Through the Membrane Surrounding Amniotic Fluid in the Rabbit
Chang, Jin-Keun, Lee, Sang-Jin, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 1호 2 13-26 (14 pages)
To study the regulation of amniotic fluid volume and electrolyte concentration by the Membranes surrounding the amniotic fluid, the rate of Li+ disappearance from amniotic sac of expired fetuses were examined while increasing the amniotic volume and osmolarity in rabbits. After intraamniotic injection of 1 ml isosmotic saline (about 20% of the amniotic fluid volume) containing 15 mM LiCl and 0.5 g/L Censored, the time courses of Li+ and Censored disappearance were determined. From there the Li+... -
소금 섭취량을 달리한 정상 및 고혈압쥐에서 Atrial Natriuretic Peptide가 혈압, Renin-Aldosterone 및 신배설에 미치는 영향
전제량(Juhn, Jae-Ryang), 이원정(Lee, Won-Jung), 박재식(Park, Jae-Sik), 주영은(Choo, Young-Eun) 대한생리학회 대한생리학회지 12 Pages
대한생리학회 대한생리학회지 1990, 제 24권 제 2호 7 319-330 (12 pages)
장기적으로 소금 섭취량을 달리 한 정상 및 고혈압쥐에서 atrial natriurectic peptide (ANP) 가 혈압, renin-aldosterone 및 신배설에 미치는 효과를 비교하였다. 생후 6주된 spontaneously hyper-tensive rate (SHR)와 Wistar 숫쥐를 각각 저염, 정상염 및 고염 (2, 10, 25 mmol NaCl/100g diet) 군으로 나누어 실험 식이를 6주동안 먹었다. 실험 당일 아침에 쥐를 ether로 마취시킨 상태에서 대퇴 동맥과 정맥 및 방광에 catheter를 삽입한 다음에 쥐를 restraining cage에 넣어 고정시켰다. 마취가 깨고 혈압이 안정된 후에... -
The study of osteoinductive effect as the variant rhBMP-2 application in the dorsal subcutaneous tissue of white rat
Yoon- Seon Keum, Hyo-Jeong Son, Seung- Cheol Woo, Jang-Yeol Lee, Hyoun-Chull Kim, Sang-Chull Lee, Jingo Kusukawa 대한치과이식임플란트학회 Journal of Dental Implant Research 7 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2010, 제 29권 1호 7 47-53 (7 pages)
The study of the osteoinductive effect during the implantation in the bone defect area has been carried out, also the bone morphogenetic protein(BMP) has been taken notice of osteoinduction material. Urist (1965) was the first to report the presence of bone morphogenetic protein (BMP) that was detected by transplantation of decalcified bone matrix into an intramuscular site, where it induced ectopic ossification. The term “bone morphogenetic protein”(BMP) was introduced to describe the... -
A preliminary study of bone inducing effect by recombinant bone morphogenetic protein-2
Hyo-Jeong Son, Jang-Yeol Lee, Seung-Cheol Woo, Hyoun-Chull Kim, Sang-Chull Lee, Jingo Kusukawa 대한치과이식임플란트학회 Journal of Dental Implant Research 6 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2010, 제 29권 1호 6 41-46 (6 pages)
In bone grafting, autogenous bone is considered the 'gold standard' to which other method are compared. The limitations of obtaining autogenous bone are obvious. Allograft, xenofraft and synthetic bone graft are widely used, but they have not solved all the problems in bone grafting. Generally, allograft or synthetic bone graft has lower healing capacity than autograft and carries a risk for certain disease, such as hepatitis or AIDS1). Occasionally, incomplete healing is seen in spite of proper... -
고령 환자의 즉시 하중 임프란트의 성공률 및 변연골 변화에 관한 후향적 연구
전용민 대한치과이식임플란트학회 Journal of Dental Implant Research 14 Pages
대한치과이식임플란트학회 Journal of Dental Implant Research 2009, 제 28권 1호 2 10-23 (14 pages)
대한민국의 65세 이상의 고령인구는 2008년 7월 현재 전체 인구의 10.3%를 차지하고 있다. 또한, 통계청의 장 래인구추계에 따르면, 대한민국은 지난 2000년에 이미 65세 이상 인구가 총인구에서 차지하는 비중이 7.2%에 이르러‘고령화 사회’에 들어섰으며, 오는 2019년에는 이 비율이 14%를 넘어‘고령사회’에 진입할 것으로 전 망하고 있다1). -
Effect of Stimulus Rate and Gender on Auditory Brainstem Response in Korean Young Adults
Chul-Hee Choi, Ki-Hyeon Jang, Seong Hee Choi 한국청각언어재활학회 Audiology and Speech Research 16 Pages
한국청각언어재활학회 Audiology and Speech Research 2015, 제 11권 제 2호 5 140-155 (16 pages)
The main objective of this study was to determine the effect of stimulus rate and gender on auditory brainstem response (ABR) latency and amplitude in Korean young adults. A total of thirty young adults consisting of fifteen males and fifteen females participated in the study. We performed this study by analyzing the latencies and amplitudes of ABR wave I, Ⅲ, and V as a function of low stimulus rate and gender. The stimulus repetition rate was changed in five steps: 8, 16, 21, 32, and 64/s....
