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총 144건 검색
본문검색 결과만 보기
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The Molecular Basis and Physiological Implications of Red Cell Deformability
Chien, Shu 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1991, 제 25권 제 2호 1 101-114 (14 pages)
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동아시아 두 섬의 신화와 전통주거 공간과의 상관성: 제주도와 오키나와의 화신(火神)의 신화와 부엌의 공간을 중심으로
이석주, 김영주 한국종교교육학회 종교교육학연구 14 Pages
한국종교교육학회 종교교육학연구 2022, 제 71권 13 233-246 (14 pages)
연구 목적 본 연구의 목적은 제주도와 오키나와의 신화에 투영된 두 섬의 전통민가에서 부엌의 공간과 화신(火神)의 의미를 연계해서 분석하는 것이다. 연구 내용 본 연구에서는 두 섬사람들은 그들의 신화의 내용에 근거해서 지었던 주거공간과 화신의 의미를 섬의 자연환경에 적합한 형태로 해석했다. 이러한 사유방식은 궁극적으로 이들에게 자연과 인간이 소통할 수 있는 결정적인 계기를 제공했다. 두 섬의 신화는 섬에서 생활하는 섬사람들의 실생활의 정서와 믿음을 반영하고 있다. 이같은 문화적 요소의 특징이 ‘원망의... -
니까야에 나타난 업설(業說) 고찰: 업설의 용례와 유형
한국종교교육학회 종교교육학연구 2022, 제 71권 11 193-209 (17 pages)
연구 목적 본 논문은 니까야에 나타난 업설의 용례와 유형에 대한 고찰을 통해 업설의 진정한 의미를 살펴보는 것이 목적이다. 불교의 업설은 과거 행위가 현재에 영향을 미친다는 점에서 종종 운명론이라는 주장이 있으므로 업설에 대한 분석을 통해 이를 고찰하고자 한다. 연구 내용 니까야에 나타난 대표적인 업설은 과거의 행위로 인해 현재의 업보를 받는다는 것이다. 불교에서 업보는 인과법을 대표하는데, 후대 불교에서는 지옥에 떨어지는 등의 과보를 업의 결과라고 본다. 본고에서는 초기불전인 니까야 중 붓다의 업에 대한... -
기(氣)는 동양에서 수천 년 동안 자연과 사회, 물질과 정신을 아우르며 만물의 변화를 설명하는 개념으로 쓰여 왔다. 이 논문은 사이언스 월든의 ‘똥본위화폐’ 연구 프로젝트에서 똥의 순환과 가치 정립에 대한 인문학적 이론기반을 마련하기 위한 연구이다. 특히 이 논문은 화담 서경덕의 기철학을 중심으로 똥의 가치와 의미를 논하고 있다. ‘똥본위화폐’ 프로젝트가 기철학에서 얻을 수 있는 사고는 첫째 순환적 사고이다. 특히 장자, 장횡거, 서화담은 만물의 변화를 기의 취산으로 설명하면서 모든 존재가 거대한 순환에서...
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Osteokinematic analysis during shoulder abduction using the C-arm
Seung Hoo Lee, Young-hoon Kim, Dong Geon Lee, Kyeong-Bong Lee, Gyu Chang Lee 물리치료재활과학회 Physical Therapy Rehabilitation Science 6 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 4호 9 208-213 (6 pages)
Objective: Despite reliable evidence of abnormal scapular motions increases, there is not yet sufficient evidence of abnormal humeral translations. This study aims to analyze the motion of the humeral head toward the scapula when the shoulder is actively abducted using the C-arm. Design: A case report. Methods: The participant was a healthy man without any limitation and pain during shoulder movement. The participant’s shoulder was abducted; this movement in the frontal plane was measured using... -
The clinical efficacy of thoracolumbar fascia release for shoulder pain
Don Mo Choi, Ji Hye Jung 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2015, 제 4권 제 1호 10 55-59 (5 pages)
Objective: This study aimed to elucidate the effects of thoracolumbar fascia release (TLFR) on the degree of pain and disability in patients with shoulder pain. Design: Randomized control trial. Methods: Thirty subjects with shoulder pain participated in this study. They were allocated to TLFR group (n=15) and manual physical therapy (MPT) group (n=15). Shoulder pain and disability index (SPADI) and the score on the visual analogue scale (VAS) were measured before and after TLFR. Results: In the... -
Prevention and Intervention of Adolescents’ Maladaptive Internet use
Oh Yeon Ju 경인교육대학교 교육연구원 The Journal of Education 15 Pages
경인교육대학교 교육연구원 The Journal of Education 2019, Vol.2 No.2 1 1-15 (15 pages)
This article presents the characteristics of addiction, cognitive behavior, and social cognitive perspectives, which are the mainstream views of maladaptive Internet use. As the academic branch dealing with mental health, such as psychology and psychiatry, first raised the issue of maladaptive Internet use and continued research, views in the context of mental health, such as addiction and cognitive behavior perspectives, have become mainstream. The mental health perspective, however, shows... -
Korean Jeju ‘Byungkyul’, Citrus platymamma Hort.et Tanaka, Prevents Hepatocellular Carcinoma Hep3G Cells Propagation and Survival
Gyeong Eun Hong, Silvia Yumnam, Ho Jeong Lee, Suchismita Raha, Venu Venkatarame Gowda Saralamma, Jeong Doo Heo, Sang Joon Lee, Gon Sup 대한수의학회 대한수의학회 학술대회발표집 2 Pages
대한수의학회 대한수의학회 학술대회발표집 춘계학술심포지움 156 219-220 (2 pages)
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An overview of calf diarrhea - infectious etiology, diagnosis, and intervention
Yong-il Cho, Kyoung-Jin Yoon* 대한수의학회 Journal of Veterinary Science 17 Pages
대한수의학회 Journal of Veterinary Science 2014, 제 15권 제 1호 1 1-17 (17 pages)
Calf diarrhea is a commonly reported disease in young animals, and still a major cause of productivity and economic loss to cattle producers worldwide. In the report of the 2007 National Animal Health Monitoring System for U.S. dairy, half of the deaths among unweaned calves was attributed to diarrhea. Multiple pathogens are known or postulated to cause or contribute to calf diarrhea development. Other factors including both the environment and management practices influence disease severity or... -
Sporozoite proteome analysis of Cryptosporidium parvum by one-dimensional SDS-PAGE and liquid chromatography tandem mass spectrometry
AMAM Zonaed Siddiki* 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 2호 1 107-114 (8 pages)
Despite the development of new technologies, new challenges still remain for large scale proteomic profiling when dealing with complex biological mixtures. Fractionation prior to liquid chromatography tandem mass spectrometry (LC-MS/MS) analysis is usually the preferred method to reduce the complexity of any biological sample. In this study, a gel LC-MS/MS approach was used to explore the stage specific proteome of Cryptosporidium (C.) parvum. To accomplish this, the sporozoite protein of C.... -
Application of biotechnological tools for coccidia vaccine development
Wongi Min, Rami A. Dalloul, Hyun S. Lillehoj 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 4호 1 279-288 (10 pages)
Coccidiosis is a ubiquitous intestinal protozoan infection of poultry seriously impairing the growth and feed utilization of infected animals. Conventional disease control strategies have relied on prophylactic medication. Due to the continual emergence of drug resistant parasites in the field and increasing incidence of broiler condemnations due to coccidia, novel approaches are urgently needed to reduce economic losses. Understanding the basic biology of host-parasite interactions and... -
Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice
Sung Ho Kim, Jong Hwan Lee, Yun Sil Lee, Cha Soo Lee, Tae Hwan Kim, Se Ra Kim, Dae Won Bang, Heon Oh 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2002, 제 3권 제 1호 2 7-11 (5 pages)
The objective of this investigation was to evaluate dose-incidence relationships on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed on day 11.5 after conception, coincident with the most sensitive stage for the induction of major congenital malformations, with 0.5-4.0 Gy of gamma- radiations. The animals were sacrificed on day 18 of gestation and the fetuses were examined for mortality, growth retardation, change in head size and any other morphological abnormalities.... -
Influence of gestational age at exposure on the prenatal effects of gamma-radiation
Sung-ho Kim, Se-ra Kim, Yun-sil Lee, Tae-hwan Kim, Sung-kee Jo, Cha-soo Lee 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2001, 제 2권 제 1호 6 37-42 (6 pages)
The objective of this investigation was to evaluate the influence of gestational age at exposure on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed to a single dose of 2.0 Gy gamma-radiation at a gestational 2.5 to 15.5 days post-coitus (p.c.). The animals were sacrificed on day 18 of gestation and the fetuses were examined for mortality, growth retardation, change in head size and any other morphological abnormalities. The only demonstrable effect of irradiation during... -
The clinical implication of sodium-potassium ratios in dogs
Son-Il Pak 대한수의학회 Journal of Veterinary Science 5 Pages
대한수의학회 Journal of Veterinary Science 2000, 제 1권 제 1호 9 61-65 (5 pages)
Although there have been substantial evidences on the usefulness of electrolytes for the diagnosis of disease, the evidences for a direct link between serum sodium and serum potassium in relation to a specific disease are very limited. This study was performed to investigate an association between diseases and Na:K ratios in dogs. From January 1997 to December 1999, a total of 39 cases with an Na:K ratio less than 27 were retrieved from the medical records of Veterinary Medical Teaching... -
Acute porcine reproductive and respiratory syndrome outbreaks in immunized sow herds: from occurrence to stabilization under whole herd vaccination strategy
Sung Ho Moon, Sung J. Yoo, Sang Hyun Noh, Taeyong Kwon, Dong Uk Lee, Sang H. Je, Myung Hyee Kim, Sang Won Seo, Young S. Lyoo1 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 7 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2018, 제 58권 제 2호 2 73-79 (7 pages)
Outbreaks of porcine reproductive and respiratory syndrome virus (PRRSV) in vaccinated sow herds from occurrence to stabilization were monitored and analyzed in terms of serology and reproductive performance. Three different conventional pig farms experienced severe reproductive failures with the introduction of a type 1 PRRSV. These farms had adopted mass vaccination of sows using a type 2 PRRSV modified live vaccine (MLV). Therefore, to control the type 1 PRRSV, an alternative vaccination... -
Suggestion on the Problem-based Learning Environment for Smart Learning in Pre-service Music Teacher Education
김지현(JiHyun Kim) 한국음악교육공학회 음악교육공학 13 Pages
한국음악교육공학회 음악교육공학 2014, 제 19호 12 227-239 (13 pages)
스마트폰의 확산 추세에 따라 페이스북, 트위터, 링크드인, 마이스페이스 등과 같은 다양한 소셜네트워크 서비스를 교육에 활용한 연구가 등장하고 있다. 디지털 시대에 부합하는 학습 환경 구축을 위해 본 연구는 스마트 러닝과 그 특징부터 문헌을 통해 살펴보았다. 그리고 PBL의 학습 효과를 검토하여 스마트 러닝을 위한 음악 논술 문제를 개발하였다. 이는 스마트 러닝의 학습원칙을 기반으로 한 사회적이고, 실제적이며, 테크놀로지 기반학습이 반영된 스마트-PBL 학습 환경의 구안이다. 본 연구의 결과는 예비음악교사교육에서... -
양성프로그램 증례를 이용한 체중조절에 대한 3차원적인 접근 방법에 대한 소개
최형석(Hyung Suk Choi), 최승(Seung Choi) 한방비만학회 대한한방비만학회지 16 Pages
한방비만학회 대한한방비만학회지 2006, 제 6권 제 1호 11 117-132 (16 pages)
비만은 단순한 신체적 원인 뿐 아니라 심리적, 사회적, 문화적 문제가 복합되어 있다. 따라서, 의료적 측면에 있어서도 전인적 접 근이 강조되어야 하나 서양의 치료는 주로 신체적인 문제에 집중한다. 한의학은 몸과 마음을 따로 보지 않는 전인적인 의학이며 비만과 같은 질환을 접근하는데 강점을 갖는다. 지금까지 비만환자를 위한 한의학의 전인적 접근, 즉 신체 뿐아니라 체계적으로 심리적인 접근을 하려는 노력은 많았으나 보고된 연구 성과가 드물었다. 양성치료는 동양철학과 한의학에 근거하여 비만환자를 위해 개발된 전인적... -
Patterns of Psychosocial Adaptation to Chronic Illness and Disability
Jeong Han Kim, Norman L. Berven Yves, Ambroise Summer, Ibarra Tae Sun Kim 한국교육치료학회 교육치료연구 22 Pages
한국교육치료학회 교육치료연구 2010, Vol.2 No.2 1 1-22 (22 pages)
This study examined the patterns of psychosocial adaptation to chronic illness and disability(CID), defined in terms of subjective well-being and coping strategies in a sample of 100 individuals with various CID conditions. Cluster analysis revealed four distinct clusters of respondents, suggesting a varying degree of psychosocial adaptation. These clusters were labeled succumbing(n=9), surviving(n=40), resilient(n=41), and thriving(n=10). Our findings indicate that resilient and succumbing... -
Gintonin facilitates catecholamine secretion from the perfused adrenal medulla
Seung-YeolNa, Ki-HwanKim, Mi-SungChoi, Kang-SuHa, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2016, Vol.20 No.6 9 629-639 (11 pages)
The present study was designed to investigate the characteristics of gintonin, one of components isolated from Korean Ginseng on secretion of catecholamines (CA) from the isolated perfused model of rat adrenal gland and to clarify its mechanism of action. Gintonin (1 to 30 μg/ml), perfused into an adrenal vein, markedly increased the CA secretion from the perfused rat adrenal medulla in a dose-dependent fashion. The gintonin-evoked CA secretion was greatly inhibited in the presence of... -
Role of Cerebrospinal Fluid Biomarkers in Clinical Trials for Alzheimer’s Disease Modifying Therapies
Ju-HeeKang, Na-YoungRyoo, DongWunShin, JohnQTrojanowski, LeslieM.Shaw 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.6 1 447-456 (10 pages)
Until now, a disease-modifying therapy (DMT) that has an ability to slow or arrest Alzheimer’s disease (AD) progression has not been developed, and all clinical trials involving AD patients enrolled by clinical assessment alone also have not been successful. Given the growing consensus that the DMT is likely to require treatment initiation well before full-blown dementia emerges, the early detection of AD will provide opportunities to successfully identify new drugs that slow the course of AD... -
Prolyl 4 Hydroxylase: A Critical Target in the Pathophysiology of Diseases
RaviKant, AnjanaBali, NirmalSingh, AmteshwarSinghJaggi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.2 1 111-120 (10 pages)
Prolyl 4 hydroxylases (P4H) are iron- and 2-oxoglutamate-dependent dioxygenase enzymes and hypoxia-inducible transcription factor (HIF)-P4Hs play a critical role in the regulating oxygen homeostasis in the local tissues as well in the systemic circulation. Over a period of time, a number of prolyl hydroxylase inhibitors and activators have been developed. By employing the pharmacological tools and transgenic knock out animals, the critical role of these enzymes has been established in the... -
Influence of Fimasartan (a Novel AT1 Receptor Blocker) on Catecholamine Release in the Adrenal Medulla of Spontaneously Hypertensive Rats
Hyo-JeongLim, Seog-KiLee, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 14 99-109 (11 pages)
The aim of this study was to determine whether fimasartan, a newly developed AT1 receptor blocker, can affect the CA release in the isolated perfused model of the adrenal medulla of spontaneously hypertensive rats (SHRs). Fimasartan (5∼50 ՌM) perfused into an adrenal vein for 90 min produced dose- and time-dependently inhibited the CA secretory responses evoked by ACh (5.32 mM), high K＋ (56 mM, a direct membrane depolarizer), DMPP (100 ՌM) and McN-A-343 (100 ՌM). Fimasartan... -
Comparison of Ectopic Gene Expression Methods in Rat Neural Stem Cells
WoosukKim, JiHyeonKim, Sun-YoungKong, Min-HyePark, UyDongSohn, Hyun-JungKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.1 4 23-30 (8 pages)
Neural stem cells (NSCs) have the ability to proliferate and differentiate into various types of cells that compose the nervous system. To study functions of genes in stem cell biology, genes or siRNAs need to be transfected. However, it is difficult to transfect ectopic genes into NSCs. Thus to identify the suitable method to achieve high transfection efficiency, we compared lipid transfection, electroporation, nucleofection and retroviral transduction. Among the methods that we tested, we... -
Ghrelin Protects Spinal Cord Motoneurons Against Chronic Glutamate Excitotoxicity by Inhibiting Microglial Activation
SungyoubLee, YumiKim, EndanLi, SeungjoonPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2012, Vol.16 No.1 7 43-48 (6 pages)
Glutamate excitotoxicity is emerging as a contributor to degeneration of spinal cord motoneurons in amyotrophic lateral sclerosis (ALS). Recently, we have reported that ghrelin protects motoneurons against chronic glutamate excitotoxicity through the activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3Ղ pathways. Previous studies suggest that activated microglia actively participate in the pathogenesis of ALS motoneuron... -
Effects of Erythropoietin on Memory Deficits and Brain Oxidative Stress in the Mouse Models of Dementia
RohitKumar, AmteshwarSinghJaggi, NirmalSingh 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.5 15 345-352 (8 pages)
streptozotocin (i.c.v STZ, 3 mg/kg, 10Ռl, 1st and 3rd day) in separate groups of animals. Morris water- maze test was employed to assess learning and memory. The levels of brain thio-barbituric acid reactive species (TBARS) and reduced glutathione (GSH) were estimated to assess degree of oxidative stress. Brain acetylcholinesterase enzyme (AChE) activity was also measured. Scopolamine/streptozotocin administration induced significant impairment of learning and memory in mice as indicated... -
Provinol Inhibits Catecholamine Secretion from the Rat Adrenal Medulla
Jung-HeeLee, Yu-SeungSeo, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.3 14 229-239 (11 pages)
voltage-dependent Na＋ channels, 10ՌM) were significantly reduced. Interestingly, in the simultaneous presence of provinol (1Ռg/ml) plus L-NAME (a selective inhibitor of NO synthase, 30ՌM), the CA secretory responses evoked by ACh, high K＋, DMPP, McN-A-343, Bay-K-8644 and cyclpiazonic acid recovered to the considerable extent of the corresponding control secretion in comparison with the inhibition of provinol-treatment alone. Under the same condition, the level of NO released... -
Roles of Dopaminergic D1 and D2 Receptors in Catecholamine Release from the Rat Adrenal Medulla
YoungJooBaek, YooSeongSeo, DongYoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 12 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2008, Vol.12 No.1 3 13-24 (12 pages)
The aim of the present study was designed to establish comparatively the inhibitory effects of D1-like and D2-like dopaminergic receptor agonists, SKF81297 and R(-)-TNPA on the release of catecholamines (CA) evoked by cholinergic stimulation and membrane depolarization from the isolated perfused model of the rat adrenal medulla. SKF81297 (30ՌM) and R-(-)-TNPA (30ՌM) perfused into an adrenal vein for 60 min, produced great inhibition in the CA secretory responses evoked by ACh... -
c-fos mRNA Expression in the Vestibular System following Hypergravity Stimulation in Rats
GuangShiJin, JaeHyoLee, JaeHeeLee, MoonYoungLee, MinSunKim, YuanZheJin, JeongHoonSong, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.1 1 1-7 (7 pages)
Altered environmental gravity, including both hypo- and hypergravity, may result in space adaptation syndrome. To explore the characteristics of this adaptive plasticity, the expression of immediate early gene c-fos mRNA in the vestibular related tissues following an exposure to hypergravity stimulus was determined in rats. The animals were subjected to a force of 2 g (twice earth's gravity) for 1, 3, or 12 h, and were examined poststimulus at 0, 2, 6, 12, and 24 h. RT-PCR (reverse transcription... -
R-(-)-TNPA, a Dopaminergic D2 Receptor Agonist, Inhibits Catecholamine Release from the Rat Adrenal Medulla
Soon-PyoHong, Hong-JooSeo, Dong-YoonLim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 8 273-282 (10 pages)
ACh, high K, DMPP, McN-A-343, Bay-K-8644, and cyclopiazonic acid were significantly reduced. Taken together, these experimental results suggest that R-()-TNPA greatly inhibits the CA secretion from the perfused rat adrenal medulla evoked by cholinergic stimulation (both nicotininc and muscarinic receptors) and membrane depolarization, but S()- raclopride rather enhances the CA release by them. It seems that this inhibitory of R-()-TNPA may be mediated by stimulation... -
Neurovascular Mechanisms in Stroke, Neurodegeneration and Recovery
EngH.Lo 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2006, Vol.10 No.5 1 223-230 (8 pages)
The emerging concept of the“neurovascular unit”may enable a powerful paradigm shift for neuroscience. Instead of a pure focus on the“neurobiology”of disease, an opportunity now exists to return to a more integrative approach. The neurovascular unit emphasizes that signaling between vascular and neuronal compartments comprise the basis for both function and dysfunction in brain. Hence, brain disorders are not just due to death of neurons, but instead manifested as cell signaling perturbations... -
Effects of Chlorhexidine digluconate on Rotational Rate of n-(9-Anthroyloxy)stearic acid in Model Membranes of Total Lipids Extracted from Porphyromonas gingivalis Outer Membranes
Hye-OckJang, Dong-WonKim, Byeong-IllKim, Hong-GuSim, Young-HoLee, Jong-HwaLee, Jung-HaBae, Moon-KyoungBae, Tae-HyukKwon, IlYun 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.2 3 83-88 (6 pages)
a basis for studying the molecular mechanism of pharmacological action of chlorhexidine digluconate. Large unilamellar vesicles (OPGTL) were prepared with total lipids extracted from cultured Porphyromonas gingivalis outer membranes (OPG). The anthroyloxy probes were located at a graded series of depths inside a membrane, depending on its substitution position (n) in the aliphatic chain. Fluorescence polarization of n-(9-anthroyloxy)stearic acid was used to examine effects of chlorhexidine... -
The Staging of Major Mood Disorders
Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)
with the caveat that many more articles were discovered for bipolar disorder. Current evidence points to allostatic load and neuroprogression as the basis for staging of mood disorders. Conclusion_Principal affective illnesses may be characterized by distinct stages, for instance early, intermediate and late. These phases inform the management so that clinicians should incorporate the staging schema into everyday practice and implement treatment strategies according to the phase of the illness. -
정신분열증의 양성，음성증상에 따른 추체외로증상의 비대칭성
신동원, 민성길 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 1994, 제 33권 제 5호 3 960-969 (10 pages)
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흰쥐의 위산 분비 및 실험적 괴양에 미치는 향정신성물질의 영향
대한신경정신의학회 신경정신의학 1974, 제 13권 제 1호 5 61-71 (11 pages)
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ROLE OF THE “SECURITY BLANKET” A Crosscultural-Ethological Perspective
Kang-EM, Hong 대한신경정신의학회 신경정신의학 6 Pages
대한신경정신의학회 신경정신의학 1980, 제 19권 제 1호 7 47-52 (6 pages)
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흰쥐 부신에서 카테콜아민 분비작용과 도파민 수용체간의 상관성
임동윤(Dong-Yoon Lim), 윤중근(Joong-Keun Yoon), 문백(Baek Moon) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1994, 제 30권 제 1호 10 87-100 (14 pages)
도파민 함유세포가 교감신경절에 존재하는 것으로 알려져 있으나, 말초에서 신경전달 물질로써 그의 역할과 작용기전에 대해서 아직까지 알려진 바가 많지 않다. 따라서 본 연구에서는 도파민 D2-수용체의 선택적인 효능약으로 알려진 apomorphine이 흰쥐 적출 관류 부신에서 카테콜아민(CA)분비작용에 미치는 영향을 연구코자 시도하여 다음과 같은 연구결과를 얻었다. 10μM Apomorphine의 비교적 낮은 농도를 부신정맥내에 20분간 관류 하였을때 5.32mM ACh, 56mM KCl, 100μM DMPP 및 100μM McN-A-343 등의 투여에 의한 CA... -
흰쥐 관류부신에서 Histamine 수용체 활성화가 Catecholamine 분비작용에 미치는 영향
임동윤(Dong-Yoon Lim), 노상현(Sang-Hyun Rho) 대한약리학회 대한약리학잡지 14 Pages
대한약리학회 대한약리학잡지 1993, 제 29권 제 1호 5 43-56 (14 pages)
흰쥐 관류부신에서 histamine의 catecholamine (CA) 분비작용의 특성과 기전을 규명코자 연구한 결과는 다음과 같다. Histamine (37.5 ~ 150μg)을 부신정맥내에 주사 하였을 때 현저한 용량 의존성의 CA 분비작용을 나타내었다. 그러나 histamine (150μg)을 120분 간격으로 반복 투여시 제 3차 투여시부터는 CA 분비효과가 뚜렷이 감소하였다. 즉, histamine의 반복투여로 인한 반응급강현상을 관찰할 수 있었다. Histamine의 CA 분비작용은 chlorisondamine, diphenhydrarmine, ranitidine, Ca++-free Krebs 용액의 관류, nicardipine... -
흰쥐 적출 부신에서 DMPP 및 McN-A-343의 Catecholamine 분비작용에 관한 연구
임동윤(Dong-Yoon Lim), 황두환(Doo-Hwan Hwang) 대한약리학회 대한약리학잡지 16 Pages
대한약리학회 대한약리학잡지 1991, 제 27권 제 1호 7 53-68 (16 pages)
흰쥐 적출 부신에서 DMPP와 McN-A-343의 카테콜아민(CA) 분비작용의 차이와 특성에 대해서 연구한 결과 다음과 같다. DMPP(100 uM)와 McN-A-343(100 uM)은 부신정맥내로 투여시 유의한 카테콜아민 분비작용을 나타내었다. Mol농도로 비교시 McN-A-343의 CA분비작용은 DMPP의 약 1/5정도였다. DMPP나 McN-A-343의 반복투여시 반응 급강현상은 관찰할 수 없었다. DMPP의 CA분비작용은 chlorisondamine이나 desipramine또는 Ca2+-free Krebs + EGTA 관류등의 전처치로 의의있게 억제되었으나, pirenzepine, ouabain 및 physostigmine등... -
스트레스성 궤양발생에 대한 중추 아드레날린성 활성도의 역할
김동구(Dong-Goo Kim), 고창만(Chang Mann Ko), 경춘호(Choon Ho Kyung), 홍사석(Sa Suk Hong) 대한약리학회 대한약리학잡지 8 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 3 87-94 (8 pages)
스트레스로 인한 위궤양형성에 중추성 교감신경의 영향여부를 추구하기 위하여 norepinephrine, epinephrine, dopamine, isoproterenol 및 clonidine을 흰쥐의 뇌실내로 투여 하고 한냉 환경 (4˚C)에서 4시간 구속방치하여 위 분비기능의 변동과 궤양 발생 정도를 검색하여 다음과 같은 결과를 얻었다. 1. Norepinephrine, epinephrine, dopamine및 소량의 clonidine 처치로 궤양 발생이 현저하게 감소하였다. 2. Norepinephrine또는 epinephrine 처치군에서는 위액분비, 산분비 및 펩신 분비의 감소와 궤양 발생 감소가 초래되었다. 3.... -
Neuroendocrine Control of Gonadotropin Secretion during the Menstrual Cycle
Ryu Kyung-Za 대한약리학회 대한약리학잡지 20 Pages
대한약리학회 대한약리학잡지 1987, 제 23권 제 2호 1 57-76 (20 pages)
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해명(海冥) 회종편(回腫片)에서 Morphine과 Naloxone 작용(作用)에 미치는 전해질(電解質)의 영향(影響)
권용춘(Yong-Chon Kwon), 은홍배(Hong-Bae Eun), 조규박(Kyu-Park Cho) 대한약리학회 대한약리학잡지 11 Pages
대한약리학회 대한약리학잡지 1983, 제 19권 제 2호 7 57-67 (11 pages)
Guinea-Pig의 myenteric plexus-longitudinal muscle preparation에서 morphine과 naloxone 효과(效果)에 미치는 전해질(電解質)의 영향(影響)을 관찰(觀察)하였다. 표본(標本)은 Krebs-Henseleit bicarbonate tufter solution 으로 채운 organ bath에 현수(懸垂)하고 0.2Hz로 전기자극(電氣刺戟)하였다. Morphine은 전기자극(電氣刺戟)에 의(依)한 근편수축(筋片收縮)을 억제(抑制)하였으며, 이때 ID30은 약(約) 190nM이었다. 이와같은 morphine의 억제작용(抑制作用)은 bath내(內) Na+ 또는 K+ 농도(濃度)를 감소(減少)시키거나 Mg2+을... -
d-Amphetamine이 백서뇌의 5-HT, 5-HIAA, MAO 및 행동에 미치는 영향에 관한 연구
서유헌(Yoo Hun Suh), 우종인(Jong In Woo)박찬웅(Chan Woong Park) 대한약리학회 대한약리학잡지 16 Pages
대한약리학회 대한약리학잡지 1981, 제 17권 제 2호 6 47-62 (16 pages)
d-amphetamine이 사람에서 paranoid schizophrenia와 아주 유사한 model psychosis를 일으키며 또한 사람과 실험동물에서 실제 정신분열증에서 뚜렷이 관찰되는 behavioral perservation을 일으킬 수 있음이 관찰되었다. 이에 많은 학자들은 이러한 양상의 행동변화가 정신분열증의 원인 추구에 중요한 의미를 주는 뇌변화를 반영할지도 모른다는 생각에 많은 연구를 거듭하여 왔다. 지금까지는 주로 catecholamine기전에 대하여 집중적 연구가 수행되어져 왔으나 최근에는 d-amphetamine의 약리기전의 일부는 5-HT기전이 차지하고... -
A Comparison of Shortening and Shortening Speed in Sartorius, Gastrocnemius and Rectus Abdominis Muscles of Uromastix hardwickii
Fehmeena, S., Azeem, M. Abdul 대한생리학회 대한생리학회지 10 Pages
대한생리학회 대한생리학회지 1994, 제 28권 제 1호 6 61-70 (10 pages)
A new method is used to record the actual shortening produced during the auxotonic activity of the sartorius (SAR), gastrocnemius (CAS) and rectus abdominis (RAB) muscles of a lizard Uromastix. The auxotonic twitch and tetanus records thus obtained were used for the first time to calculate the coefficient of linear shortening (COLS). This coefficient represent the relative Index between change in length (Δ L=L0-L1) and tension (ΔP P0-P1) due to shortening at the steepest rising phase of the... -
Cardiovascular Neurons Mediating Somatosympathetic Reflex in Rostral Ventrolateral Medulla
Goo, Yong-Sook, Kim, Sang-Jeong, Kim, Jun, Sung, Ho-Kyung 대한생리학회 대한생리학회지 14 Pages
대한생리학회 대한생리학회지 1993, 제 27권 제 2호 7 185-198 (14 pages)
The rostral ventrolateral medulla (RVLM) includes vasopressor neurons, which transmit activation signals to the intermediolateral nucleus (IML) of the spinal cord, where the preganglionic sympathetic nucleus is located, to raise arterial blood pressure (BP). However, controversy exists as to the possible depressor area in the RVLM and the pathway involved. The present study persued evidence far the location of depressor neurons and the pathway by simultaneously observing changes in BP and the... -
Potential of Using Ginger Essential Oils-Based Nanotechnology to Control Tropical Plant Diseases
Adamu Abdullahi, Khairulmazmi Ahmad, Intan Safinar Ismail, Norhayu Asib, Osumanu Haruna Ahmed, Abubakar Ismaila Abubakar, Yasmeen Siddiqui, Mohd Razi Ismail 한국식물병리학회 The Plant Pathology Journal 21 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 6호 1 515-535 (21 pages)
Essential oils (EOs) have gained a renewed interest in many disciplines such as plant disease control and medicine. This review discusses the components of ginger EOs, their mode of action, and their potential nanotechnology applications in controlling tropical plant diseases. Gas chromatography-mass spectroscopy (GC-MS), high-performance liquid chromatography, and headspace procedures are commonly used to detect and profile their chemical compositions EOs in ginger. The ginger EOs are composed... -
Systematic Investigation of the Effects of Macro-elements and Iron on Soybean Plant Response to Fusarium oxysporum Infection
Hongsheng Cai, Nan Tao, Changhong Guo 한국식물병리학회 The Plant Pathology Journal 8 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 5호 2 398-405 (8 pages)
experiments were conducted, assessing disease suppression by selected combinations of macro-elements and Fe at screened concentrations, i.e., K (9 mM) plus Fe (0.2 mM), and S (4 mM) plus Fe (0.2 mM). The disease index was significantly reduced by the combination of K plus Fe. In conclusion, this systematic investigation of soybean plant responses to F. oxysporum infection provides a solid basis for future environmentally-friendly choices for application in soybean disease control programs. -
Genetic Diversity Studies and Identification of Molecular and Biochemical Markers Associated with Fusarium Wilt Resistance in Cultivated Faba Bean (Vicia faba)
Amer F. Mahmoud, Bahaa E. S. Abd El-Fatah 한국식물병리학회 The Plant Pathology Journal 18 Pages
한국식물병리학회 The Plant Pathology Journal 2020, 36권 1호 2 11-28 (18 pages)
Faba bean (Vicia faba L.) is one of the most important legume crops in Egypt. However, production of faba bean is affected by several diseases including fungal diseases. Fusarium wilt incited by Fusarium oxysporum Schlecht. was shown to be the most common wilt disease of faba bean in Assiut Governorate. Evaluation of 16 faba bean genotypes for the resistance to Fusarium wilt was carried out under greenhouse conditions. Three molecular marker systems (inter-simple sequence repeat [ISSR], sequence... -
Computer-Aided Drug Discovery in Plant Pathology
한국식물병리학회 The Plant Pathology Journal 14 Pages
한국식물병리학회 The Plant Pathology Journal 2017, 33권 6호 1 529-542 (14 pages)
Control of plant diseases is largely dependent on use of agrochemicals. However, there are widening gaps between our knowledge on plant diseases gained from genetic/mechanistic studies and rapid translation of the knowledge into target-oriented development of effective agrochemicals. Here we propose that the time is ripe for computer-aided drug discovery/design (CADD) in molecular plant pathology. CADD has played a pivotal role in development of medically important molecules over the last three...
