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전체 선택해제
총 205건 검색
본문검색 결과만 보기
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Development of Fully-Implantable Middle Ear Hearing Device with Differential Floating Mass Transducer : Current Status
Cho. Jin-Ho, Park. Il-Yong, Lee. Sang-Heun 대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 9 Pages
대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 2005, Vol.26 No.5 309-317 (9 pages)
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Design of Implantable Microphone for Artificial Middle Ear System
Kim. Min-Kyu, Lim. Hyung-Gyu, Yoon. Young-Ho, Lee. Jyung-Hyun, Park. Il-Yong, Song. Byung-Seop, Kim. Myoung-Nam, Cho. Jin-Ho 대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 6 Pages
대한의용생체공학회 Journal of biomedical engineering research : the official journal of the Korean Society of Medical & 2005, Vol.26 No.3 139-144 (6 pages)
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Role of Radiotherapy for Squamous Cell Carcinoma of the External Auditory Canal and Middle Ear
강현철, 우홍균, 이지혜, 박찬일, 김종선, 오승하, 허대석, 김동완, 이세훈, Kang. Hyun-Cheol, Wu. Hong-Gyun, Lee. Ji-Hye, Park. Charn-Il, Kim. Chong-Sun, Oh. Seung-Ha, Heo. D 대한방사선종양학회 대한방사선종양학회지 8 Pages
대한방사선종양학회 대한방사선종양학회지 2009, Vol.27 No.4 173-180 (8 pages)
목 적: 본 연구에서는 외이도 및 중이에 생긴 편평상피암의 치료에 있어서 방사선치료의 역할에 대해 알아보고자 한다. 대상 및 방법: 1981년부터 2007년까지 외이도 및 중이에 생긴 편평상피암으로 치료 받은 총 35명의 기록을 후향적으로 분석하였다. 13명은 방사선치료 단독, 4명은 수술 단독, 18명은 수술 방사선 병용 요법으로 치료하였다. 방사선치료 단독군에서 조사된 중앙 방사선량은 66 Gy (범위, 39~70 Gy)이었고, 수술 방사선 병용 치료군에서는 61.2 Gy (범위, 44~70 Gy)를 조사하였다. 치료 방법에 따른 질병특이생존율 및... -
Genomic-based identification of novel potential biomarkers and molecular signaling networks in response to diesel exhaust particles in human middle ear epithelial cells
Kwon. Jee Young, Park. Moo Kyun, Seo. Young Rok, Song. Jae-Jun 대한독성유전단백체학회 Molecular & cellular toxicology 11 Pages
대한독성유전단백체학회 Molecular & cellular toxicology 2014, Vol.10 No.1 95-105 (11 pages)
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Diagnosis and Characterization of Middle-ear and Cochlear Functions
Rong Z. Gan 한국청각언어재활학회 Audiology and Speech Research 18 Pages
한국청각언어재활학회 Audiology and Speech Research 2013, 제 9권 제 2호 1 95-112 (18 pages)
Hearing impairment is one of the most common physical disabilities in the world. Conductive hearing loss results from dysfunction of the middle ear, and sensorineural hearing loss results from abnormalities within the cochlea or central nervous system. To improve the diagnosis of hearing loss and develop new technologies for restoration of hearing, changes of the middle ear and cochlear functions in relation to ear structural disorders in hearing impaired ears need to be characterized. This... -
Virtual otoscopy for evaluating the inner ear with a fluid-filled tympanic cavity in dogs
Youngkwon Cho, Jimo Jeong, Haebeom Lee, Minsu Kim, Namsoo Kim, Kichang Lee* 대한수의학회 Journal of Veterinary Science 6 Pages
대한수의학회 Journal of Veterinary Science 2012, 제 13권 제 4호 12 419-424 (6 pages)
were easily and clearly distinguished except for the incus and stapes of the clinical patients. VO images were not more suitable than images created with conventional CT for accurately diagnosing otitis media in this study. However, it appears that VO could be more feasible for assessing the complex structure of the inner ear in dogs with fluid-filled tympanic cavities since fluid accumulation within the tympanic bulla did not affect the evaluation of bony tissue in the middle ear on VO images. -
Effect of Stimulus Rate and Gender on Auditory Middle Latency Response in Young Adults
Ki-Hyeon Jang, Seong Hee Choi, Chul-Hee Choi 한국청각언어재활학회 Audiology and Speech Research 7 Pages
한국청각언어재활학회 Audiology and Speech Research 2017, 제 13권 제 2호 3 108-114 (7 pages)
Purpose: The main objective of this study was to investigate the effect of stimulus rate and gender on the latency and amplitude of the auditory middle latency response (AMLR) in Korean young females and males. Methods: A total of thirty young subjects consisting of fifteen males and fifteen females participated in the study. The stimulus repetition rate was changed in five steps: 0.5, 1, 2, 4, and 8/s. Results: The results showed significant differences of the stimulus rates on the Na latency,... -
Some Key Aspects of the Buddhist Philosophy of Education
Asanga Tilakarane 한국종교교육학회 종교교육학연구 14 Pages
한국종교교육학회 종교교육학연구 2007, 제 25권 10 127-140 (14 pages)
This paper aims to outline a few key issues that demand our attention if we are interested in developing a Buddhist philosophy of education. The paper begins with a plea for caution for those who are of the view that there is a ready-made theory of education, fully and explicitly articulated by the Buddha, in his teachings. What we have at the most is insights and examples that can be used in constructing a philosophy of education. In fact such a philosophy of education is possible on the... -
Comparison of the effects of muscle stretching exercises and cupping therapy on pain thresholds, cervical range of motion and angle
Jong-eun Yim, Jun-hyuck Park, Hong-seop Kim, Ju-yeon Woo, So-yeong Joo, Su-min Lee, Je-won Song 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2017, 제 6권 제 2호 6 83-89 (7 pages)
Objective: Computers and smartphones have become a necessity for modern people, and the use of these things in an inappropriate position has increased the number of people who complain about neck problems. The purpose of this study was to compare the changes of cervical angle, range of motion (ROM) and pain threshold according to the McKenzie stretching and dry cupping therapy. Design: Cross-over design. Methods: We included 12 male and 6 female college students in their twenties, and conducted... -
Comparison on postural control between abdominal draw-in maneuver and abdominal expansion maneuver in persons with stroke
Ho-Suk Choi, Yu-Jin Shim, Won-Seob Shin 물리치료재활과학회 Physical Therapy Rehabilitation Science 7 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2016, 제 5권 제 3호 1 113-119 (7 pages)
Objective: The effect of abdominal expansion maneuver (AEM) and abdominal draw-in maneuver (ADIM) on postural control in an unsupported position in stroke patients. Design: Randomized controlled trial. Methods: A total of 36 persons with hemiplegic stroke participated in this study. The subjects were randomly divided into an AEM experimental group (n=12), an experimental ADIM group (n=12), and a control group (n=12). We collected the general characteristics of all subjects and the pre-test... -
The effect of physical training on glutamate transporter expression in an experimental ischemic stroke rat model
Gye-Yeop Kim, Eun-Jung Kim 물리치료재활과학회 Physical Therapy Rehabilitation Science 5 Pages
물리치료재활과학회 Physical Therapy Rehabilitation Science 2013, 제 2권 제 2호 5 87-91 (5 pages)
a middle cerebral artery occlusion (MCAO)-induced ischemia injury rat model. Design: Randomized controlled trial. Methods: In this study, we randomly divided them into three groups. Group I included non-occlusion sham controls (n=10), Group II included non-physical training after MCAO (n=10), and Group III included rats that were subjected to physical training after MCAO (n=10). Rats in the physical training group underwent treadmill training, which began at 24 h after MCAO and continued for 14... -
Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells
Jingpeng Gao, Chunchun Meng, Zongyan Chen, Chuanfeng Li, Guangqing Liu 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 4호 10 441-447 (7 pages)
Rabbit hemorrhagic disease (RHD) is contagious and highly lethal. Commercial vaccines against RHD are produced from the livers of experimentally infected rabbits. Although several groups have reported that recombinant subunit vaccines against rabbit hemorrhagic disease virus (RHDV) are promising, application of the vaccines has been restricted due to high production costs or low yield. In the present study, we performed codon optimization of the capsid gene to increase the number of preference... -
Electroretinography recordings using a light emitting diode active corneal electrode in healthy beagle dogs
Yoshiki Itoh, Seiya Maehara, Norihiko Itoh*, Kazuto Yamashita, Yasuharu Izumisawa 대한수의학회 Journal of Veterinary Science 8 Pages
대한수의학회 Journal of Veterinary Science 2013, 제 14권 제 1호 11 77-84 (8 pages)
Electroretinography (ERG) is a well-established diagnostic procedure for objectively evaluating retinal function. In this study, ERG in beagle dogs, which are a popular experimental animal, was performed to determine the normal range of ERG variables and assess differences between the left and right eyes. ERG findings including rod, combined rod-cone, single-flash cone, and 30-Hz flicker responses were recorded with an LED-electrode in 43 sedated beagle dogs. The subjects were divided into young... -
Evaluation of glycoproteins purified from adult and larval camel ticks (Hyalomma dromedarii) as a candidate vaccine
Amr E. El Hakim, Yasser E. Shahein*, Sobhy Abdel-Shafy, Amira M. K. Abouelella, Ragaa R. Hamed 대한수의학회 Journal of Veterinary Science 7 Pages
대한수의학회 Journal of Veterinary Science 2011, 제 12권 제 3호 7 243-249 (7 pages)
In order to identify antigens that can help prevent camel tick infestations, three major glycoproteins (GLPs) about 97, 66 and 40 kDa in size were purified from adult and larval Egyptian ticks, Hyalomma (H.) dromedarii, using a single-step purification method with Con-A sepharose. The purified GLPs were evaluated as vaccines against camel tick infestation in rabbits. The rabbits received three intramuscular inoculations of GLPs (20 mg/animal) on days 0, 14, and 28. In the immunoblot analysis,... -
Inherited canine copper toxicosis in Australian Bedlington Terriers
Changbaig Hyun and Lucio John Filippich 대한수의학회 Journal of Veterinary Science 10 Pages
대한수의학회 Journal of Veterinary Science 2004, 제 5권 제 1호 4 19-28 (10 pages)
Inherited copper toxicosis in Bedlington Terriers (CTBT) is a copper associated hepatopathy caused by an autosomal recessive genetic defect of gene involving copper metabolism. To compare clinical and histopathological findings with previous reports and to expand our knowledge for future genetic studies, 18 terriers were clinically and histopathologically examined in this study. Pedigree information and dietary history were obtained from the owners before a thorough clinical examination was... -
Genetic and biological characteristics of recent Korean isolates of avian influenza virus subtype H9N2
Madhav Prasad Acharya , Hyuk Joon Kwon , Il Hwan Kim , Youn Jeong Lee , Jae Hong Kim 대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 8 Pages
대한수의학회 Korean Journal of Veterinary Research(구 대한수의학회지) 2012, 제 52권 제 4호 1 223-230 (8 pages)
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Improvisation in Collegiate Class Piano
Jungeyun Grace Choi 한국음악교육학회 음악교육연구 17 Pages
한국음악교육학회 음악교육연구 2022, 제 51권 제 1호 8 159-175 (17 pages)
The purpose of this research was to investigate an aural approach to improvisation in collegiate class piano. A total of 15 undergraduate students enrolled in their first year of class piano participated in the semester-long study. At the end of instruction, each student performed and improvised two tunes both vocally and instrumentally. Three independent judges rated recordings of student performances using rating scales designed to measure tonal, rhythm, expressive, and improvisation skills.... -
FGI 기초 연구를 바탕으로 한 온라인 음악 수업 개발 방향 탐색
민경훈, 임은정 한국음악교육학회 음악교육연구 21 Pages
한국음악교육학회 음악교육연구 2021, 제 50권 제 3호 2 35-55 (21 pages)
이 연구의 목적은 비대면 온라인 음악 수업 콘텐츠 개발의 이론적 토대를 마련하고 학교음악 수업 현장에 적용 가능한 효율적 온라인 콘텐츠 개발의 방향을 제시하는데 있다. 연구 방법은 초⋅중⋅고 음악 교사를 대상으로 비대면 집단심층면접(Focus Group Interview)을 실시하였으며 온라인 서면 응답과 실시간 영상 면접을 통해 조사 자료를 수집하였다. 조사 자료는 FGI질문 문항과 답변 내용에 따라 주요 주제 단위로 온라인 음악 수업 콘텐츠 개발을 위한 구체적방안으로 제시되었다. 연구결과 온라인 음악수업 콘텐츠는... -
예술 교과 교육과정의 내용 체계 연구
한국음악교육학회 음악교육연구 2020, 제 49권 제 1호 8 175-203 (29 pages)
본 연구의 목적은 고등학교 예술 교과 교육과정의 구조와 내용을 분석하여 교육과정 구성의 문제점 파악과 개선점을 제안하는데 있다. 연구는 2015 고등학교 교육과정 ‘보통교과 영역’의 예술 교과군 7개 교과목과 ‘전문교과Ⅰ영역’의 예술 계열 교과군 40개 교과목으로 총 47개 예술 교과의 교육과정들을 대상으로 하였다. 연구 과정은 예술 교과 교육과정의 내용 체계를 추출하고, 이에 따라 각 예술 교과 교육과정의 내용을 비교 분석하였다. 연구결과 2015 고등학교 예술 교과 교육과정은 총론의 주요 교육 중점 및 방향을 충분히... -
시각장애 음악전공자들의 회고를 바탕으로 한 음악 교수방법론 탐색
김미정(Mi Jung Kim), 박휴용(Hyu Yong Park) 한국음악교육학회 음악교육연구 32 Pages
한국음악교육학회 음악교육연구 2013, 제 42권 제 3호 6 151-182 (32 pages)
본 논문은 시각장애를 가진 음악가 혹은 학생들이 음악을 가르치고 익히는 과정에 활용하는 네 가지의 교수수단, 즉 청각입력을 통한 암기, 구두지도, 촉각정보, 그리고 기술적 도구들에 대해 논의하였다. 본 논문은 시각장애인이 이러한 교수수단을 통해 음악을 익히는 과정을 매개(mediation), 숙달(mastery)과 전유(appropriation)의 개념적 틀을 통해 분석하였으며, 이 네 가지 방법들이 매개수단(mediational means)으로써 음악을 배우고 익히는데 활용되고 있음을 논의하였다. 저자들은 참여연구를 통해서 서울의 한 맹학교... -
생명과학 학습에서 디지털 콘텐츠의 유형에 따라 생성된 과학적 의문의 분석
권승혁, 엄증태, 권용주 한국교원대학교 뇌기반교육연구소 Brain & Learning 11 Pages
한국교원대학교 뇌기반교육연구소 Brain & Learning 2014, 제 4권 제 2호 1 1-11 (11 pages)
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구순구개열 미션 시 구개열 수술에 대한 분석
박영욱, 이석근, 권광준, 김성곤, 팽준영, 황대석, 김좌영 대한구순구개열학회 대한구순구개열학회지 6 Pages
대한구순구개열학회 대한구순구개열학회지 2020, 제 23권 1호 3 14-19 (6 pages)
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비주 결손의 범위에 따른 피판의 선택과 재건
송상현, 조혜민, 박진후, 정휘동, 정영수 대한구순구개열학회 대한구순구개열학회지 6 Pages
대한구순구개열학회 대한구순구개열학회지 2018, 제 21권 1호 5 23-28 (6 pages)
Congenital and acquired columella defect is rare. Columella is a small subunit of the nose, but determines the projection of nasal tip, defines the nasolabial angle, and is related to the structural relationship between alar rims and the nasal base. The showing of columella from various angles is also important for aesthetic point of view. Thus, reconstruction of columella defect is quite challengeable operation for surgeons. The recipient site should be harmonious with surrounding area, also... -
구개열 환자에 있어 중이염의 치료
방강미, 지영민, 김성민, 명훈, 최진영, 이종호, 정필훈, 김명진, 황순정 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2007, 제 10권 2호 4 89-95 (7 pages)
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피부이식편을 보존하기 위한 양수 효능에 대한 고찰
김주현, 김성민, 오진실, 명훈, 이종호, 최진영 대한구순구개열학회 대한구순구개열학회지 7 Pages
대한구순구개열학회 대한구순구개열학회지 2011, 제 14권 1호 4 37-43 (7 pages)
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Treatment Protocol for Cleft Lip and/or Palate Children in Kyushu University Hospital
Akira Suzuki 대한구순구개열학회 대한구순구개열학회지 13 Pages
대한구순구개열학회 대한구순구개열학회지 2012, 제 15권 2호 3 69-81 (13 pages)
for a feeding plate. The cheiloplasty is performed in three months old. (2) From lip repair to palatal repair At one year of age, Otorhinolaryngologist checks middle-ear disease. Palatoplasty is carried out at 1.5 - 2 years old. (3) In deciduous and early mixed dentitions Speech is the most important issue in social life for the CL/P subjects, therefore the training of velopharyngeal function is essential. Orthodontist monitors dentofacial development from 5 years of age. In the case of severe... -
From Learning Disabilities to Learning Difference : Applying Narrative Therapy for College Students Labeled “Learning Disabilities”
Dong Hun Lee 한국교육치료학회 교육치료연구 8 Pages
한국교육치료학회 교육치료연구 2009, Vol.1 No.2 6 71-78 (8 pages)
In recent decades western psychology has conceptualized learning disabilities (LD) in terms of deficits and related ‘social emotional issues’ as insecurity, low self-esteem and social isolation that can be rehabilitated through combined remedial teaching and psychological intervention. Consequently, most research regarding college students with LD tend to characterize these students in terms of problems they encounter or deficits they exhibit. Such research does not paint a rich portrait of... -
Reduction of long-term potentiation at Schaffer collateral-CA1 synapses in the rat hippocampus at the acute stage of vestibular compensation
GyoungWanLee, JaeHyoKim, MinSunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 8 423-428 (6 pages)
Vestibular compensation is a recovery process from vestibular symptoms over time after unilateral loss of peripheral vestibular end organs. The aim of the present study was to observe time-dependent changes in long-term potentiation (LTP) at Schaffer collateral-CA1 synapses in the CA1 area of the hippocampus during vestibular compensation. The input-output (I/O) relationships of fEPSP amplitudes and LTP induced by theta burst stimulation to Schaffer’s collateral commissural fibers were... -
Elucidation of the profound antagonism of contractile action of phenylephrine in rat aorta effected by an atypical sympathomimetic decongestant
EldinaRizvi, GoranJankovi, MiroslavM.Savi 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 11 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2017, Vol.21 No.4 4 385-395 (11 pages)
Vasoconstrictive properties of sympathomimetic drugs are the basis of their widespread use as decongestants and possible source of adverse responses. Insufficiently substantiated practice of combining decongestants in some marketed preparations, such are those containing phenylephrine and lerimazoline, may affect the overall contractile activity, and thus their therapeutic utility. This study aimed to examine the interaction between lerimazoline and phenylephrine in isolated rat aortic rings,... -
Effect of Vestibulosympathetic Reflex and Baroreflex on Expression of pERK in the Nucleus Tractus Solitarius following Acute Hypotension in Conscious Rats
XianJiang, YanLan, Yuan-ZheJin, JooYoungPark, ByungGeonPark, AbdulNasirAmeer, ByungRimPark 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2014, Vol.18 No.4 11 353-358 (6 pages)
Control of blood pressure is maintained by the interaction between the arterial baroreflex and vestibulosympathetic reflex during postural changes. In this study, the contributions of vestibular receptors and baroreceptors to the maintenance of blood pressure following acute hypotension were compared in terms of phosphorylated extracellular regulated protein kinase (pERK) expression in the nucleus tractus solitaries (NTS). Expression of pERK in the NTS was measured in conscious rats that had... -
Additive Role of the Vestibular End Organ and Baroreceptors on the Regulation of Blood Pressure in Rats
YanLan, Yan-ZhaoYang, XianJiang, Li-WeiLi, Guang-ShiJin, MinSunKim, ByungRimPark, Yuan-ZheJin 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2013, Vol.17 No.4 15 367-373 (7 pages)
Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or baroreceptor unloading. BL attenuated baroreflex sensitivity during intravenous infusion of sodium... -
c-Fos Expression in the Nucleus of the Solitary Tract in Response to Salt Stimulation in Rats
YonghoKwak, Mee-RaRhyu, SunJoonBai, , YoungHeeSa, MinJeeKwon, , BaeHwanLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 16 437-444 (8 pages)
six subregions in each of bilateral NST were compared between applications of distilled water and different concentrations of NaCl to the tongue of experimental animals. From this study, salt stimulation with high concentration (1.0 M NaCl) induced significantly higher c-Fos expression in intermediate NST and dorsal-medial and dorsal-middle subregions of the NST compared to distilled water stimulation. The result represents the specific spatial distribution of salt taste perception in the NST. -
Cigarette Smoke Extract-induced Reduction in Migration and Contraction in Normal Human Bronchial Smooth Muscle Cells
ChulHoYoon, Hye-JinPark, Young-WooCho, Eun-JinKim, JongDeogLee, KeeRyeonKang, JaeheeHan, DawonKang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2011, Vol.15 No.6 11 397-404 (8 pages)
The proliferation, migration, cytokine release, and contraction of airway smooth muscle cells are key events in the airway remodeling process that occur in lung disease such as asthma, chronic obstruction pulmonary disease, and cancer. These events can be modulated by a number of factors, including cigarette smoke extract (CSE). CSE-induced alterations in the viability, migration, and contractile abilities of normal human airway cells remain unclear. This study investigated the effect of CSE on... -
Neuroprotection by Valproic Acid in Mouse Models of Permanent and Transient Focal Cerebral Ischemia
YongRiQian, Mu-JinLee, ShinaeHwang, JiHyunKook, Jong-KeunKim, ChoonSangBae 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2010, Vol.14 No.6 13 435-440 (6 pages)
pre- and post-insult treatments with VPA protect against brain infarct and neurological deficits in mouse transient (tMCAO) and permanent middle cerebral artery occlusion (pMCAO) models. In the tMCAO (2 hr MCAO and 22 hr reperfusion) model, intraperitoneal injection of VPA (300 mg/kg, i.p.) 30 min prior to MCAO significantly reduced the infarct size and the neurological deficit. VPA treatment immediately after reperfusion significantly reduced the infarct size. The administration of VPA at 4 hr... -
Nitric Oxide Modulation of GABAergic Synaptic Transmission in Mechanically Isolated Rat Auditory Cortical Neurons
Jong-JuLee 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 7 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.6 9 461-467 (7 pages)
The auditory cortex (A1) encodes the acquired significance of sound for the perception and interpretation of sound. Nitric oxide (NO) is a gas molecule with free radical properties that functions as a transmitter molecule and can alter neural activity without direct synaptic connections. We used whole-cell recordings under voltage clamp to investigate the effect of NO on spontaneous GABAergic synaptic transmission in mechanically isolated rat auditory cortical neurons preserving functional... -
Microarray Analysis of Differentially Expressed Genes in the Brains of Tubby Mice
JeongHoLee, ChulHoonKim, DongGooKim, YoungSooAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 8 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2009, Vol.13 No.2 4 91-98 (8 pages)
The tubby mouse is characterized by progressive retinal and cochlear degeneration and late-onset obesity. These phenotypes are caused by a loss-of-function mutation in the tub gene and are shared with several human syndromes, suggesting the importance of tubby protein in central nervous system (CNS) functioning. Although evidence suggests that tubby may act as a transcription factor mediating G-protein coupled receptor (GPCR) signaling, any downstream gene regulated by tubby has yet to be... -
Tetanus-induced LTD of Developing MNTB-LSO Synapses in Rat is Dependent on Postsynaptic Ca2+
SeungCheolAhn 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2007, Vol.11 No.3 1 79-84 (6 pages)
Because synaptic refinement of medial nucleus of trapezoid body (MNTB) - lateral superior olive (LSO) synapses is most active during the first postnatal week and the long term depression (LTD) has been suggested as one of its mechanisms, LTD of MNTB-LSO synapses was investigated in neonatal rat brain stem slices with the whole cell voltage clamp technique. In Mg2 free condition, tetanus (10 stimuli at 10 Hz for 2 min) in the current clamp mode induced a robust LTD of isolated D,... -
Activation of Vestibular Neurons Projecting to Autonomic Brain Stem Nuclei Following Acute Hypotension in Rats
DongOkChoi, ChonIlYon, MyoungAeChoi, ByungRimPark, MinSunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 6 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 2004, Vol.8 No.4 2 181-186 (6 pages)
Extracellular regulated protein kinase1/2 (pERK1/2) is one of the major regulatory factors for transcription of the c-fos oncogene in neurons. The purpose of this study was to evaluate the expression of phosphorylated ERK1/2 within the vestibular nuclei (VN) of rats following acute arterial hypotension. Following the acute arterial hypotension induced by rapid hemorrhage, a significant number of pERK1/2-immunoreactive neurons appeared bilaterally in the caudal aspect of the medial and inferior... -
Role of Adenosine in the Activation of Myocardial Catalase Induced by Brief Regional Ischemia
Young-hoonKim, Chan-hyungKim, Gi-taeKim, HongChoi, Jong-wanPark, Myung-sukKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 5 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 7 53-57 (5 pages)
This study was undertaken to elucidate the possible involvement of adenosine in the stimulation of myocardial catalase induced by the brief regional ischemia in rabbit hearts. Coronary artery descending the middle anterior wall of left ventricle was occluded for 15 min, followed by 1 hr of reperfusion. Upon reperfusion after the brief ischemia, the activity of catalase increased significantly in both ischemic and non-ischemic parts of myocardium. Pretreatment of the heart with theophylline, a... -
Mechanism of Membrane Hyperpolarization by Extracellular K+ in Resistance-sized Cerebral Arterial Muscle Cell of Rabbit
SeHoonKim, KunMooChoi, HoeSukKim, ByeongHwaJeon, SeokJongChang 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 10 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1999, Vol.3 No.1 1 1-10 (10 pages)
We sought to find out the mechanism of vascular relaxation by extracellular K concentration ([K]o) in the cerebral resistant arteriole from rabbit. Single cells were isolated from the cerebral resistant arteriole, and using voltage-clamp technique barium-sensitive K currents were recorded, and their characteristics were observed. Afterwards, the changes in membrane potential and currents through the membrane caused by the change in [K]o was observed. In the smooth... -
Role of Phospholipase A2 in Oxidant-induced Alteration in Phosphate Transport in Primary Cultured Rabbit Renal Proximal Tubule Cells
KwonMooPark, SunHeeKo, JaeSukWoo, JinSupJung, SangHoLee, YongKeunKim 대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 9 Pages
대한생리학회-대한약리학회 The Korean Journal of Physiology & Pharmacology 1998, Vol.2 No.5 8 601-609 (9 pages)
The present study was undertaken to examine the role of phospholipase A2 (PLA2) in oxidant-induced inhibition of phosphate transport in primary cultured rabbit renal proximal tubule cells. Uptakes of phosphate and glucose were dose-dependently inhibited by an oxidant t-butylhydroperoxide (tBHP), and the significant inhibition appeared at 0.025 mM of tBHP, whereas tBHP-induced alterations in lipid peroxidation and cell viability were seen at 0.5 mM. tBHP stimulated arachidonic acid (AA) release... -
The Staging of Major Mood Disorders
Ather Muneer, Rana Mazommil 대한신경정신의학회 Psychiatry Investigation 12 Pages
대한신경정신의학회 Psychiatry Investigation 2018, 제 15권 제 8호 2 747-758 (12 pages)
Objective_Staging of psychiatric disorders is gaining momentum and the purpose of this review is to examine whether major mood disorders can be defined according to stages. Methods_In April 2018 the PubMed electronic data base was scrutinized by a combination of various search terms like “major depressive disorder and staging,” “bipolar disorder and neuroprogression,” etc. To incorporate the latest findings the search was limited to the last 10 years. Both original and review articles were... -
화상환자의 심리적 반응에 관한 연구
이현정, 안동현, 유태혁, 박현선 대한신경정신의학회 신경정신의학 9 Pages
대한신경정신의학회 신경정신의학 1998, 제 37권 제 6호 15 1158-1166 (9 pages)
화상 환자는 화상후 경과 시간에 따라 차례로 생리적 위급의 시기, 심리적 위급의 시기, 사회적 위급의 시 기를 경험하게 된다. 본 연구에서는 88명의 환자들을 위의 세 단계로 구분하여 각 단계별로 불안, 우울, SCL-90-R을 이용한 다양한 측면에서의 심리 반응, 병동내 활동상황, 화상후 신체상의 변화를 살펴 본 결 과 다음과 같은 결론을 얻었다. 1) 화상 후 불안은 시일 경과에 따른 단계 간에 차이를 보이지 않았다. 우울은 화상후 퇴원전까지 시일이 지나감에 따라 단계적인 증가를 보였으며, 가족내 갈등, 저학력 등이 변이... -
부정적 감정이 청각적 언어상상에 의해 유발된 대뇌 피질 활성에 미치는 영향
김지웅, 이홍식, 김찬형 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 2호 12 390-401 (12 pages)
연구목적： 타인이 자신에게 말하는 것을 상상하는 청각적 언어상상은 환청과의 관련성 여부로 주목을 받아왔다. 신경 생리학 및 기능적 뇌영상술의 발달과 더불어, 청각적 언어상상과 환청과의 관련성도 신경과학적 방법으로 연 구되고 있으며, 환청이 자기감시체계의 이상이라고 주장하는 일부 학자들은 청각적 언어상상과 관련된 뇌활 성화 소견을 이용하여 환청의 병리기전을 밝히고자 하였다. 그런데 대부분의 환청의 내용은 부정적 감정을 동반하는 내용이다. 이런 점에서 저자는 부정적 감정이 청각적 언어상상에 의한 대뇌활성에... -
습관 장애가 동반된 주의력결핍/과잉운동장애 아동에서의 구안파신 약물 효과에 대한 예비연구
Youngshin Kim, Lawrence Scahill, James Leckman 대한신경정신의학회 신경정신의학 12 Pages
대한신경정신의학회 신경정신의학 2000, 제 39권 제 5호 11 908-919 (12 pages)
연구목적： 주의력결핍/과잉운동장애(이하 ADHD)와 틱장애는 소아기에 발생하는 흔한 신경정신과 질환이며 또한 두 장애는 자주 같이 동반되어 나타나는 질환이다. ADHD에서의 중추신경자극제의 효능은 이미 잘 알려져 있지 만 약 25%의 ADHD 환자는 이 계통의 약물에 효과가 없거나 틱의 악화를 포함한 심각한 부작용으로 중추 신경자극제 약물치료를 할 수 없다. 선택적 α2A 효현제인 guanfacine이 최근에 ADHD 아동의 치료에 도입 되어 사용되고 있다. 이 연구는 ADHD와 습관장애가 공존하는 아동에서 guanfacine의 효능과 안정성을... -
Neural Substrates of Motor Imagery： Event-related Functional MRI Study
Seung-Schik Yoo, Byung Gil Choi, Kyu-In Chung, Chang-Uk Lee 대한신경정신의학회 신경정신의학 10 Pages
대한신경정신의학회 신경정신의학 2001, 제 40권 제 6호 25 1247-1256 (10 pages)
연구목적： 본 연구의 목적은 가상운동 과정시 대뇌 어느 부위가 활성화되는지를 알아보기 위하여 사건-관련 기능적 자기 공명영상을 통해 평가하였다. 방 법： 9명의 오른손잡이 정상인들에게 뇌 전 영역을 포괄한 일련의 T2강조 자기공명 영상을 얻기 위해 1.5 Tesla 자 기공명 영상장치를 사용하였다. 음성 자극 신호에 따라 오른손을 쥐는 상상을 하게 한 후, 그 결과 발생하는 가상 운동과 연관된 혈중 산화 수준-의존성 신호 변화들을 측정하였다. 결 과： 측정된 자료를 group 분석한 결과 내측 상부 전두회, 설상엽, 도, 중 /...
