After introduction of percutaneous transfemoral arteriographic method by Seldinger in 1953, angiocardiographic technique has been improved and nowadays angiocardiography is a essential confirmative diagnostic procedure in various inflammatory and neoplastic disease as well as in cardiovascular disease. At department of Radiology, Seoul National University Hospital, in total 618 patients, angiocardiographic study were done from August 1971 to September 1976. Age and sex distribution, angiographic technique, disease entity classification, diagnostic accuracy and complications were comprehensively analyzed. 1. Among total 618 patients. 389 patients were male and 229 were female. Age distribution was even from 1 month to 39 year. Decreased number over age of 40. 2. Among total 824 angiocardiographic study, cardiac angiography were 269 cases, theracic aorta and its branch arteriography 67 cases abdominal aorta and its branch arteriography 67 cases, abdominal aorta and its branch 33 cases extremity arteriography 68 cases and venography including vena cavography were 81 cases. 3. Each disease entity classification reveals 83 cases of T.O.F., 39 cases of of renal cyst, ect. 4. 18 cases of angiocardiographic failure were experienced and failure rate. is 2.9%. 5. 4 cases of major complications were noted. 2 patients died, and mortality rate is 0.3%. 6. Among total 618 cases, correct diagnosis was possible in 547 cases and diagnostic accuracy was 88.5%. 7. Angiocardiography is a safe and accurate diagnostic procedure in all cardiovasular disease as well as other inflammatory and neoplastic disease.