In an endeavour to assess scintigraphic features of leukemia a retrospective analysis of hepatosplenic scintigrams using 99mTc-Sn phytate was made in 12 cases of chronic myelocytic leukemia and 6 cases of acute myelocytic leukemia. Diagnosis was proven in every case in bone marrow aspirate and peripheral blood tests. The age of patient ranged from 18 to 72 years old. there were 12 males and 6 females. 1. The great majority (83.3%) of the patient with chronic myelocytic leukemia revealed less radionuclide activity (RNA) in the spleen than in the liver, although the spleen was moderately to markedly enlarge. The RNA distribution both in the liver and spleen was inhomogeneous, but no focal defect was observed. Those findings indeed comtrasted with those of chronic leukemia and liver cirrhosis in which splenic RNA is typically more prominent than hepatic RNA. 2. All of the patient with acute myelocytic leukemia showed mild splenomegaly. The splenic RNA was equal in density to that of the liver in 66.7% and less in the remainder.