The modern mammography can demonstrate non-palpable breast lesion, such as a small mass, microcalcification and/or distortion of architecture. The preoperative localizaton of the lesion is necessary and it minimizes operation time and the size of biopsy required, permiting a better cosmetic result. Needle/Wire localization method is simple, safe, and accurate method to remove suspicious lesion. Team approach between surgeon, radiologist and pathologist is always necessary for adequate biopsy of non-palpable areast lesion. In Cheil General Hospital, 6 cases of non-palpable lesions can be demonstrated by mammography and biopsied accurately under localization by curved-end retractable wire. Of the 6 cases, 2 cases were malignant, one was intraductal carcinoma, . the other was tubular carcinoma without metastasis in axillary node. The remains were benign lesions.