In recently the gastroesophageal reflux disease(GERD) has been known to induce the otolaryngologic manifestations. Pharyngeal neurosis is a disease which we could have not found the cause frequently. So we have studied the relation between the pharyngeal neurosis and the GERD among 50 patients who were diagnosed as pharyngeal neurosis after esophagogram and laryngoscopic examination. We performed esophageal manometry and 24hour double-probe pH-metry and then compared with normal control group(n=30). The results are as follows 1 Among 50 patients, 12(24%) patients were diagnosed as GERD by DeMeester scoring. 2. In esophageal manometry, the upper and lower esophageal sphincter between the patients and the control group have no significant difference(p>0.05) and 9 among 50 pateints showed abnormal peristaltic movement in esophageal body contraction. 3. In 24hour double-probe pH-metry, the esophageal probe showed that in GERD group(n= 12) the number of reflux episode, episodes greater than 5 minutes and the percentage of time<pH4, the longest reflux time were all significantly increased compared with non GERD or control group(p<0.05). But the pharyngeal probe showed that in GERD group(n= 12) the percentage of time pH<4, total reflux episode number were significantly increased than control group(p<0.05) especially in upright position than supine position. 4. Among 12 GERD patients, 5 patients showed that the pharyngeal pH dropped below pH4 following the esophgeal pH dropped pH<4. We found that the pharyngeal neurosis may partly from the laryngopharyngeal symptom from the gastroesophageal reflux and we need more data and investigate the other laryngopharyngeal reflux disease by using 24hour double-probe pH-metry.