Refuse incineration plant operations involve many kinds of uncertain factors, such as the variable physical properties of refuse as fuel and the complexity of the burning phenomenon. This makes it very dificult to apply conventional control methods to the combustion control of the refuse. So most of the refuse incineration plant are operated by operators. In this paper, an multi-variable fuzzy model predictive controller is proposed for the combustion control of the re:fuse. Adaptive network based fuzzy inference system is used for modeling of the refuse incineration plant and multi-variable fuzzy model predictive controller is designed based on the identified fuzzy model. And computer simulation was carried out to evaluate performance of the proposed controller.