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반고형제제의 유동특성에 관한 연구 (제2보) : 바셀린의 온도의존성 유동거동
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  • 반고형제제의 유동특성에 관한 연구 (제2보) : 바셀린의 온도의존성 유동거동
  • Studies on The Flow Properties of Semi-Solid Dosage Forms (II) : Temperature-Dependent Flow Behavior of Vaseline
저자명
김정화,송기원,장갑식,이장우,이치호,Kim. Jeong-Hwa,Song. Ki-Won,Jang. Gap-Shik,Lee. Jang-Oo,Lee. Chi-Ho
간행물명
약학회지
권/호정보
1997년|41권 1호|pp.38-47 (10 pages)
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Using a concentric cylinder type, rheometer. the steady shear flow properties of vaseline were measured over the temperature range of 20~70${circ}$C. In this paper, the shea rate and temperature dependencies of its flow behavior were investigated and the validity of some flow models was examined. In addition, the flow characteristics over a wide temperature range were quantitatively evaluated by calculating the various material parameters. Main findings obtained from this study can be summarized as follows: (1) At relatively lower temperature range, vaseline is a plastic fluid with a yield stress and its flow behavior shows shear-thinning characteristics. (2) As the temperature increases, the value of a yield stress and the degree of shear-thinning become smaller, consequently, the Newtonian flow behavior occurs at a lower shear rate range. (3) At temperature range lower than 45${circ}$C, the flow behavior shows much stronger temperature dependence, and a larger activation energy is needed for flow. (4) The Herschel-Bulkley model is the most effective one g$^3$ to predict the flow behavior of vaseline having a yield stress. The validity of the Bingham and Casson models becomes more available with increasing temperature. The flow behavior of vaseline at temperature range higher than 45${circ}$C can be perfectly described by the Newton model.