Structural learning methods of MLP classifiers for a given application using genetic algorithms have been studied. In the methods, however, the search space for an optimal structure is increased exponentially for the physical application of high diemension-multi calss. In this paperwe propose a method of MLP classifiers using species genetic algorithm(SGA), a modified GA. In SGA, total search space is divided into several subspaces according to the number of hidden units. Each of the subdivided spaces is called "species". We eliminate low promising species from the evoluationary process in order to reduce the search space. experimental results show that the proposed method is more efficient than the conventional genetic algorithm methods in the aspect of the misclassification ratio, the learning rate, and the structure.structure.