In this study, active muffler was designed and was manufactured for exhaust noise reduction of commercial vehicle, then experiment of real vehicle was conducted. In a manufactured active muffler, because the flow of exhaust noise in tail pope outlet are become a plane wave, the global reduction if radiation noise from outlet and the placement of error microphone to avoid the exhaust gas of high temperature could be implemented. In control algorithm, reduction of noise of engine driving frequency and harmonic frequency can be archieved using proposed reference signal including a fixed speed state(2,000rpm, 3,000rpm, 4,000rpm) and a run-up speed state(2,000rpm$ ightarrow$4,000rpm) is accomplished with the active muffler installed in vehicle.