This study is to develope the quantitative risk assessment program for consequence analysis of fire and explosion (PML-Chem), which is applicable to the chemical plants. The advantages of PML-Chem is easy to use and acquire results. Especially, PML-Chem was embedded real weather condition database for major chemical plants in ${igcirc}{igcirc}$ complex in country. Also, reliability of PML-Chem was verified through comparing PML-Chem with PHAST-Professional which is already commercial.