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Clomiphene Citrate와 FSH 또는 Clomiphene Citrate와 hMG의 연속병합에 의한 배란유도주기에서 인공수정 후 임신율의 비교
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  • Clomiphene Citrate와 FSH 또는 Clomiphene Citrate와 hMG의 연속병합에 의한 배란유도주기에서 인공수정 후 임신율의 비교
  • Sequential Clomiphene Citrate and FSH compared to Clomiphene Citrate and hMG on Pregnancy Rate in Intrauterine Insemination Cycles
저자명
정구성,홍기언,유승환,이현숙,이종인,허영문,전은숙,윤정임,홍정의,이지삼,Jung. Goo-Sung,Hong. Ki-Eon,You. Seung-Hwan,Lee. Hyeon-Sook,Lee. Jong-In,Hur. Young-Mun,
간행물명
大韓不妊學會雜誌
권/호정보
1999년|26권 3호|pp.433-440 (8 pages)
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대한생식의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Objective: To evaluate the effectiveness of CC+FSH or CC+hMG in intrauterine insemination (IUI) cycles for the treatment of infertility. Method: Patients received daily 100 mg of clomiphene citrate (CC) for 5 days followed by hMG or FSH. A single IUI was performed at 36 h after hCG. Clinical pregnancy was classified if a gestational sac or fetal cardiac activity was seen on ultrasound. Results: The overall clinical pregnancy rate was 19.1% per cycle (17/89) and 21.5% per patient (17/79). More clinical pregnancies were recorded in CC+FSH (23.1%, 6/26) than CC+ hMG cycles (17.5%, 11/63), but this difference was not statistically significant. No differences were found in age, duration of infertility, follicle size, levels of estradiol ($E_2$) on the day of hCG injection and total motile sperm counts between pregnant and non-pregnant groups. However, more ampules of gonadotropins were used in pregnant group than non-pregnant group (p<0.05). Conclusion: Combination of CC and hMG may economically be more effective to induce ovulation for IUI compared to CC and FSH.