This study was conducted to investigate the effect of natural resources against growth of oral bacteria. The CHJ-5 strain was isolated from oral cavity of dental patients. Similarity index values of oral bacterium CHJ-5 was 0.876 to E. faecalis by cellular fatty acid analysis(Analytical Services Inc., USA). As a result of investigation about the growth inhibition of 32 kinds of natural resources on E. faecalis CHJ-5. This strain was inhibited by Schizamdrae fructus, Coptidis rhizoma and Caryophylli flos. Minimal inhibitory concentrations of Schizamdrae fructus, Coptidis rhizoma and Caryophylli flos were 0.1%, 02% and 0.1% on E. faecalis CHJ-5, respectively.