In this study, evaporation pressure drop experiments were conducted with two types of plate and shell heat exchangers (P&SHE) using R-22. An experimental refrigerant loop has been established to measure the evaporation pressure drop of R-22 in a vertical P&SHE. The flow channels were formed by stacking three plates having a corrugated channel of a chevron angle of 45 dog. The R-22 flows down in one channel exchanging heat with the hot water flowing up in the other channel. The effect of the refrigerant mass flux, average heat flux, system pressure and vapor quality were explored in detail. During the experiment, the quality change between the inlet and outlet of the refrigerant channel ranges from 0.03 to 0.15. The present data showed that two types of P&SHE have similar trends. The pressure drop in-creases with the vapor quality for both types of P&SHE. At a higher mass flux, the Pressure drop is higher for the entire range of the vapor quality. Also, the increase in the average heat flux increases the pressure drop. Finally, at a higher system pressure, the pressure drop is found to be slightly lower compared to the lower system pressure.