Melange yams were prepared by varing the ratio of raw cotton dyed with Indigo, Gardenia and Sappan wood colorants, respectively. The antibacterial activity and deodorization on melange yarns were evaluated for bacteria reduction rate and deodorization rate. The bacterial reduction rate on melange yarns was explored with Staphylococcus aureus, Klebsiella pneumoniae. The melange yarns on the ratio of raw cotton dyed with Sappan wood and Indigo showed high Staphylococcus aureus reduction rate of 99% and 90%, regardless of Al-mordanting treatment, but those with Gadenia hardly showed bacteria reduction rate. The melange yarn showed high Klebsiella pneumoniae reduction rate of 99% for Al-mordanting treatment with Sappan wood. The others were poor. The deodorization of 81% and 98∼99% obtained with melange raw sliver and melange sliver dyed with Indigo, Gardenia and Sappan wood colorants, but dyeing did not significantly affect deodorization rate.