The coefficient of variation(CV) which is a relatively dimensionless measure of variability is widely used to describe the variation of sample data. However, the properties of CV distribution are little available and few research has been done on estimation and interpretation of CV. In this paper, we give an outline of statistical properties of coefficient of variation and design of control chart based on this statistic. Construction procedures of control chart are presented. The proposed control chart is an efficient method to monitor a process variation for short production run situation. Futhermore, we evaluated the performance of CV control chart by average run length(ARL).