- A Novel Drug Delivery System Design for Meloxicam
- A Novel Drug Delivery System Design for Meloxicam
- ㆍ 저자명
- Kim. Hyun-Jo,Lee. Il-Kyu
- ㆍ 간행물명
- 藥劑學會誌
- ㆍ 권/호정보
- 2005년|35권 3호|pp.151-155 (5 pages)
- ㆍ 발행정보
- 한국약제학회
- ㆍ 파일정보
- 정기간행물|ENG| PDF텍스트
- ㆍ 주제분야
- 기타
A drug delivery system(DDS) for practically insoluble meloxicam was developed and evaluated by dissolution study. A novel DDS is two layered system, where the first layer is consisted of gas-forming agent for an immediate release and the second layer is composed of metolose SR(HPMC) for sustained release. This bilayered tablets were manufactured by using manual single punch machine. The results of dissolution study showed an initial burst release followed by sustained release for the experimental period time. From a pharmaceutical point of view, the designed DDS for meloxicam would be informative system in terms of poorly soluble analgesic medicines.