With the common objective to improve process productivity and product quality, statistical process control (SPC) and engineering process control (EPC) have been widely used in the discrete-parts industry and the process industry, respectively. The major focus of SPC is on process monitoring, while that of EPC is on process adjustment. The emergence of the hybrid industry necessitates a synergistic combination of the two methods for an effective process control. This paper investigates the existing studies on SPC, EPC, and the integration of the two methods. This paper also presents future research issues in this field.