Purpose: The purpose of this study was to determine the effect of ADL exercise in stroke patients and to define to strategy to promote their self-care ability, decrease to their family burden. Method: The experimental design was designed nonequivalent control group non-synchronized design. The study method had been done by investigating the experimental group and control group through the questionaire on 33 patients. ADL exercise was conducted by the researcher and was carried out experimental group once per day for 20 minutes for daily 28 days. Results: For the ADL exercise, self-care ability score was increased and family burden score was decreased significantly. Conclusion: The exercise increased the self-care ability and effect of family burden of stroke patients. Based upon these results, it is recommended that the nurses who take care of stroke patient carry out them the ADL exercise continuously.