In this paper, we propose a systematic procedure to determine standard time and cycle time in a TFT-LCD factory. The proposed procedure mainly consists of data preprocessing, hypothesis testing and Group technology. Data preprocessing extracts relevant data from large on-line data sets by eliminating corrupt and noisy data. Hypothesis test techniques have been used to determine whether the standard information has been changed. Also, Group technology has been applied to generate standard information for newly developed products. The proposed procedure has been successfully applied to the production information system of a TFT-LCD factory in Korea.