Recently, the reliability are applied for many industrial products, and many products are required to guarantee in quality and in performance. The purpose of this paper is to present some of reliability prediction methodologies using failure rate database for machinery parts that are applicable to machine tools. VDI Turret, which is core component of the NC Lathe, was chosen as the target of the reliability prediction. The results of reliability prediction has shown the failure rate, MTBF(Mean Time Between Failure), and reliability of the VDI Turret. It is expected that proposed methodologies will be applicable to prediction of reliability for other components of machine tools.