Purpose: This study was conducted to describe and analyze about the degree of job satisfaction of nurses in a university hospital for basic data to develop the professionals and improve productivities, effectiveness in nursing practice. Methods: Design was the descriptive survey study. Sample were 97 nurses in K university hospital, and convenient sampling was used. Measures were job satisfaction of nurse for job satisfaction tool modified by Kim, S.N.(1998) and developed by Slavitt(1978). Data were collected from April 2005 to June 2005, and analyzed using SPSS PC+12 program. Descriptive statistics was used for general characteristics and characteristics related to job. F-test, t-test, and $X^2$ test were used for verification of differences. Results: 1. Scores in categories of job satisfaction were ranked for professional position(3.25), interpersonal relationship(3.19), autonomy(3.08), necessary job(2.88), payment and promotion(2.79), and administration(2.50) in order. 2. There were significant differences in age(F=3.343, p=.040) and satisfaction for current job(F=10.331, p=.000) in differences of job satisfaction by general characteristics and characteristics related to job. Conclusions: On the findings, authors suggest that more opportunities for direct nursing practice, appropriate time for the practice, and the intervention improving satisfaction for current job are needed to improve job satisfaction.