Operation of human-centered robot, in general, facilitates the creation of new process that may potentially harm the human operators. Design of safety-guaranteed operation of human-centered robots is, therefore, important since it determines the ultimate outcomes of operations involving safety of human operators. This study discusses the application of geometric tolerance and head injury criteria to safety assessment of human-centered robotic operations. Examples show that extending "Work Area" has more significant effect on the uncertainty in safety than extending the system range in the presence of velocity control.