- 동물모델을 이용한 Hydrogel Patch의 상처치유개선 능력 평가
- ㆍ 저자명
- 오승석,김철준,김희숙,신영희,Oh. Seung-Seok,Kim. Chul-Jun,Kim. Hee-Sook,Shin. Young-Hee
- ㆍ 간행물명
- 藥劑學會誌
- ㆍ 권/호정보
- 2009년|39권 1호|pp.55-58 (4 pages)
- ㆍ 발행정보
- 한국약제학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
Sodium polyacrylate based hydrogel patch was prepared and its wound healing efficacy in comparison with control groups was evaluated in thermal burn wound ($200^{circ}C$, 10 sec burn) and excision wound rat model. Cytotoxicity of gamma irradiated (25 kGy) hydrogel patch was investigated in human fibroblasts and showed no significant cytotoxicity. Wound closure rates (H50%) in hydrogel patch group and BAND-$AID^{(R)}$ treated group were faster than that of control group (uncovered open wound). Hydrogel patch showed an enhancement in wound healing process.