Purpose: This study examined the effects of Testicular Self-Examination (TSE) small-group education on knowledge, self-efficacy, and performance intention in male college students. Method: A non-equivalent pre-post test of quasi-experimental design was used. Out of 74 male college students selected by convenient sampling, 37 students were assigned to the experimental group and were given TSE small-group education. A 60-minute program consisted of lecture, demonstration, practice, discussion, and Q&A. Result: With an initial homogeneity between the two group, scores of knowledge about testicular cancer (p<.001), self-efficacy for TSE (p<.001), and performance intention of TSE (p<.01) of the experimental group were significantly higher than those of the control group after the intervention. Conclusion: Small group education for TSE was effective in improving knowledge about testicular cancer, self-efficacy for TSE, and intention to perform TSE. Thus, this education program is considered to be useful for testicular cancer prevention and reproductive health promotion in male college students.