This study aimed to evaluate musculoskeletal workload associated with the work of hair designers, to identify the factors associated with work-related stress, depression and musculoskeletal symptoms in Hair Designers, and to check the painful areas based on patients who complained of musculoskeletal symptoms. The data were collected from 279 hair designers in Daegu metropolitan city from February 1 to August 31 of 2009. A summary of the results was as follows : According to work-related stress in study subjects, the degree of stress load was relatively higher in association with the working demand, the relational conflicts and the organizational culture, but the degree of stress was found to be relatively lower in association with the physical environment, work-related autonomy, an insufficient compensation and an occupational instability. People engaged for beauty business have gotten lots of stress because of the endless needs from customers, the pressure of the learning new skills and the uncomfortable working environment. These are able to cause the musculoskeletal disorder. Under this circumstance, small fries do not have any prevention managements for improving the musculoskeletal diseases and they are not afforded to have regular checkup. When teaching the people related with beauty business, it is necessary to provide accurate information like correct carriage to reduce musculoskeletal disorder stress.