This research aims at conducting a comparative study on the relative efficiency of technologically innovative activities between manufacturing and service industries using data envelopment analysis (DEA). First, as an individual approach, efficiency of technologically innovative activities between manufacturing and service industries is separately evaluated. The results show that efficiency of both industries is similarly low, but patterns of technologically innovative activities differ from each other. Manufacturing industries usually do innovation focusing on various outputs with a single input, whereas service industries tend to do innovation emphasizing on a single output with mixed inputs. Second, as a holistic approach to both industries, efficiency is collectively assessed. The analysis demonstrates that efficiency of service industries is higher than that of manufacturing industries, and there are similar patterns of technologically innovative activities between both manufacturing and service industries. This study provides industrial managers with policy implications based on similarities and differences between manufacturing and service industries.