Purpose: This study was conducted in order to compare muscle strength and gait ability of hemodialysis patients with those of healthy adults. Methods: Data were collected through a questionnaire, by testing of muscle strength and gait ability of 40 hemodialysis patients and 40 healthy adults. $X^2$-test, t-test, and ANCOVA were used in performance of data analysis. Results: First, variables including of occupation ( $X^2$=22.40,p<.001), body weight (t=-3.72, p<.001), and BMI ( $X^2$=14.65, p<.001) differed significantly between patients in the hemodialysis group and subjects in the healthy adult group. Second, using ANCOVA analysis with correction for related variables, such as occupation, body weight, and BMI as covariates, numbers for lift/reach (F=8.15, p<.001) and sit-to-stand (F=5.47, p=.001), and both maximum safe speed (F=9.17, p<.001) and normal comfortable speed (F=8.89, p<.001) were significantly lower for patients in the hemodialysis, compared with subjects in the healthy adult group. Conclusion: According to the results, muscle strength and gait ability of patients in the hemodialysis group were lower than those of subjects inthe healthy adult group. These findings suggest the importance and necessity for an interventional exercise and rehabilitation program for hemodialysis patients.